Results 81 to 90 of about 55,475 (331)

Sterol absorption and sterol balance in phytosterolemia evaluated by deuterium-labeled sterols: effect of sitostanol treatment.

Journal of Lipid Research, 1995
Absorption of dietary cholesterol, campesterol, and sitosterol, cholesterol balance, and fecal excretion of plant sterols were determined in three unrelated patients with phytosterolemia and three healthy volunteers during constant intake of cholesterol ...
D Lütjohann, I Björkhem, U.F. Beil, K von Bergmann   +3 more
doaj   +1 more source

Crossing the Blood–Brain Barrier with Molecularly Imprinted Polymeric Nanocarriers: An Emerging Frontier in Brain Disease Therapy

Advanced Science, EarlyView.
Molecularly imprinted polymeric nanocarriers (nanoMIPs) offer robust, antibody‐mimetic platforms to overcome the blood‐brain barrier. The article surveys nanoMIP design and ligand‐directed surface engineering that harness receptor‐mediated transcytosis, and highlights therapeutic and diagnostic applications in neurodegeneration, brain tumors and ...
Ranjit De, Shuliang Shi, Kyong‐Tai Kim
wiley   +1 more source

Sea cucumber derived sulfated sterols alter glucose metabolism by promoting gluconeogenesis and reducing glycogenesis in healthy mice

Food Science and Human Wellness
Sea cucumber derived sulfated sterols significantly ameliorated insulin resistance and decreased lipid accumulation compared to plant sterols. Interestingly, our recent study found that intervention with sea cucumber sulfated sterols could significantly ...
Shanyun Yu, Teng Wang, Yingcai Zhao, Xiaoyue Li, Changhu Xue, Yuming Wang, Tiantian Zhang   +6 more
doaj   +1 more source

Selective sterol accumulation in ABCG5/ABCG8-deficient mice

Journal of Lipid Research, 2004
The ATP binding cassette (ABC) transporters ABCG5 and ABCG8 limit intestinal absorption and promote biliary secretion of neutral sterols. Mutations in either gene cause sitosterolemia, a rare recessive disease in which plasma and tissue levels of several
Liqing Yu, Klaus von Bergmann, Dieter Lutjohann, Helen H. Hobbs, Jonathan C. Cohen   +4 more
doaj   +1 more source

Hopanoids Play a Role in Membrane Integrity and pH Homeostasis in Rhodopseudomonas palustris TIE-1 [PDF]

, 2009
Sedimentary hopanes are pentacyclic triterpenoids that serve as biomarker proxies for bacteria and certain bacterial metabolisms, such as oxygenic photosynthesis and aerobic methanotrophy.
Hunter, Ryan C., Newman, Dianne K., Sessions, Alex L., Summons, Roger E., Welander, Paula V., Zhang, Lichun   +5 more
core   +3 more sources

Smart Nanoparticles Disrupting Energy Supply through Triple Mechanisms to Kill Tumors via Dual Disruption of Mitochondria and Lysosomes

Advanced Science, EarlyView.
This study introduces a biomimetic nanoplatform (MTCA@C) designed for precise cancer therapy. It targets mitochondria to induce dysfunction through photodynamic activation, while concurrently blocking mitophagy via lysosomal alkalinization. The platform further triggers methuosis, resulting in tumor cell death through vacuolization and energy pathway ...
Xiao Xu, Qiqing Huang, Yang Liu, Jinzhuo Liu, Deyi Yang, Yanni Song, Xin Han   +6 more
wiley   +1 more source

Hepatic transport and secretion of unesterified cholesterol in the rat is traced by the plant sterol, sitostanol.

Journal of Lipid Research, 1996
The hepatic uptake, transport, and secretion into bile of unesterified cholesterol cannot be directly quantitated because of extensive exchange and equilibration between different pools of unesterified cholesterol.
S J Robins, J M Fasulo, C R Pritzker, G M Patton   +3 more
doaj   +1 more source

Ultrastructural characterization (morphological and topochemical) of wood pulp fibres [PDF]

, 2007
Different electron microscopy techniques including SEM (scanning electron microscopy), FE-SEM (field emission-scanning electron microscopy), TEM (transmission electron microscopy) and Immuno-gold TEM (immuno-gold transmission electron microscopy) were ...
Fernando, Dinesh
core  

NUDT21‐mediated Alternative Polyadenylation of CDK19 Reprograms Cholesterol Biosynthesis to Drive Colorectal Cancer Progression

Advanced Science, EarlyView.
NUDT21 is overexpressed in colorectal cancer tumors and promotes colorectal cancer progression. NUDT21 promotes the production of a cyclin‐dependent kinase 19 (CDK19) mRNA isoform with a long 3′ UTR, which enhances cytoplasmic export and translation. Truncation of the CDK19 long 3′ UTR phenocopies NUDT21 loss, recapitulating the defects in cholesterol ...
Yeping Yu, Jixin Ma, Minwei Zhou, Xiaodong Gu, Yiming Zhou, Zhenyang Li, Tianyu Zhang, Wei Gong, Chuanxin Huang, Jianbin Xiang   +9 more
wiley   +1 more source