Results 191 to 200 of about 754,614 (331)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Quantitative monitoring of paramagnetic contrast agents and their allocation in plant tissues via DCE-MRI. [PDF]

open access: yesPlant Methods, 2022
Mayer S   +8 more
europepmc   +1 more source

Plant Tissue Sample NTA026905

open access: green, 2020
TERN Ecosystem Surveillance
openalex   +1 more source

Plant Tissue Sample SAA017521

open access: green, 2021
TERN Ecosystem Surveillance
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Proteomic changes in various plant tissues associated with chromium stress in sunflower. [PDF]

open access: yesSaudi J Biol Sci, 2022
Sardar R   +12 more
europepmc   +1 more source

Plant Tissue Sample SAA025269

open access: green, 2021
TERN Ecosystem Surveillance
openalex   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

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