Results 111 to 120 of about 464,525 (364)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Banana bunchy top virus movement protein induces resistance in banana against Fusarium wilt

open access: yesPhytopathology Research
Banana Fusarium wilt, which is known as Panama disease and caused by Fusarium oxysporum f. sp. cubense (Foc), is a destructive disease that can lead to plant death and complete loss of banana plantations.
Weiying Wang   +4 more
doaj   +1 more source

Viruses of cucumber isolated from some regions of Ukraine

open access: yesPlant Protection Science, 2002
Properties of viruses isolated from cucumbers in greenhouses of Ukraine are characterized in this article by electrophoresis, ELISA, electron microscopy, and immunoblotting.
A. Ryzhkova   +3 more
doaj   +1 more source

Pyramiding of Ryd2 and Ryd3 conferring tolerance to a German isolate of Barley yellow dwarf virus-PAV (BYDV-PAV-ASL-1) leads to quantitative resistance against this isolate [PDF]

open access: yes, 2011
Barley yellow dwarf virus (BYDV) is an economically important pathogen of barley, which may become even more important due to global warming. In barley, several loci conferring tolerance to BYDV-PAV-ASL-1 are known, e.g.
Broer, I.   +5 more
core   +2 more sources

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga   +2 more
wiley   +1 more source

Elimination of Tomato Spotted Wilt Virus (genus Tospovirus) From Infected Tomato Plants by Meristem Tip Culture [PDF]

open access: bronze, 2015
Maha AlKhazindar   +99 more
openalex   +1 more source

Purification and Cytopathological Effects of cucumber mosaic virus on Cucurbita pepo Plants [PDF]

open access: gold, 2021
Al-Naji Al-Mansori   +3 more
openalex   +1 more source

Visacane, an innovative quarantine tool for the exchange of pest and disease-free sugarcane germplasm [PDF]

open access: yes, 2011
Sugarcane varietal improvement can not exclusively rely upon exchange and introduction of genetic resources via true seeds (fuzz). It also requires the introduction of vegetative propagation material (cuttings, tissue-cultured plantlets).
Fernandez, Emmanuel   +4 more
core  

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