Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Agricultural biotechnology: Status and prospective [PDF]
The development of the DNA recombinant technology has provided the transfer of a single or several genes within or among species whereby organisms with new traits were developed. Such organisms have been called genetically modified organisms.
Drinić Goran +1 more
doaj
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
A review on urban agriculture: technology, socio-economy, and policy
It has been a challenge to support the expansion of urban agriculture (UA) in cities due to its poor economic profitability. However, it is also hard to deny the increasing benefits of UA in improving the socio-environmental dimension of cities.
Grace Ning Yuan +7 more
doaj +1 more source
Pharmaceutical and Industrial Traits in Genetically Modified Crops: Co-existence with Conventional Agriculture, August 2006 [PDF]
This paper discusses the implications of using genetically modified crops to biomanufacture pharmaceuticals and industrial compounds from the perspective of their co-existence with conventional agriculture. Such plant-made pharmaceuticals and plantmade
core
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Opinion Survey of Lublin University Students on Genetically Modified Plants
In recent years genetically modified plants have become a subject of discussion not only among scientists but among consumers and politicians as well.
Anna Krzepiłko +3 more
doaj +1 more source
The status and prospects for genetically modified food in Europe and Croatia [PDF]
In the last sixteen years worldwide production of genetically modified (GM) crops has been increased sharply. At the same time, consumer?s attitudes toward food products made from GM ingredients have been largely negative.
Nada KNEEVIC +2 more
doaj +1 more source

