Results 81 to 90 of about 58,273 (309)

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

FEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia, Anna Dósa, Asha Kiran Maddali, András Jipa, Hajnalka Laczkó‐Dobos, Péter Lőw, Gábor Juhász   +6 more
wiley   +1 more source

Scientific Opinion on the assessment of potential impacts of genetically modified plants on non-target organisms

, 2010
The European Food Safety Authority (EFSA) asked the Panel on Genetically Modified Organisms to establish a self-tasking Working Group with the aim of (1) producing a scientific review of the current guidance of the GMO Panel for Environmental Risk ...
EFSA Panel on Genetically Modified Organisms (GMO)
core   +1 more source

Deliberate release of genetically modified plants into the environment in Slovenia

Acta Agriculturae Slovenica, 2015
Deliberate release of genetically modified higher plants (GMHPs) into the environment in Slovenia is regulated by the Law on the Management of Genetically Modified Organisms (ZRGSO) Ur. l. RS 23/2005 and 21/2010, III chapter.
Zlata LUTHAR
doaj   +1 more source

Applicability of the EFSA Opinion on site‐directed nucleases type 3 for the safety assessment of plants developed using site‐directed nucleases type 1 and 2 and oligonucleotide‐directed mutagenesis

EFSA Journal, 2020
The European Commission requested the EFSA Panel on Genetically Modified Organisms (GMO) to assess whether section 4 (hazard identification) and the conclusions of EFSA's Scientific opinion on the risk assessment of plants developed using zinc finger ...
EFSA Panel on Genetically Modified Organisms (EFSA GMO Panel), Hanspeter Naegeli, Jean‐Louis Bresson, Tamas Dalmay, Ian Crawford Dewhurst, Michelle M Epstein, Leslie George Firbank, Philippe Guerche, Jan Hejatko, Francisco Javier Moreno, Ewen Mullins, Fabien Nogué, Jose Juan Sánchez Serrano, Giovanni Savoini, Eve Veromann, Fabio Veronesi, Josep Casacuberta, Andrea Gennaro, Konstantinos Paraskevopoulos, Tommaso Raffaello, Nils Rostoks   +20 more
doaj   +1 more source

Cultivation Restrictions for Genetically Modified Plants [PDF]

European Journal of Risk Regulation, 2016
Directive (EU) 2015/412 allows Member States to restrict the cultivation of genetically modified seed or propagating material, although their placing on the market has been authorized. This so-called opt-out is meant to resolve the current Member States’ conflict about gene technology by facilitating differences of states concerning cultivation ...
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Scientific Standards and the Regulation of Genetically Modified Insects [PDF]

, 2012
Experimental releases of genetically modified (GM) insects are reportedly being evaluated in various countries, including Brazil, the Cayman Islands (United Kingdom), France, Guatemala, India, Malaysia, Mexico, Panama, Philippines, Singapore, Thailand ...
Fiammetta Santucci, R. Guy Reeves (185792), Bryk, Jarek, Reed, F., Santucci, F., Denton, Jai A., Floyd A Reed, Jarosław Bryk, Floyd A. Reed (185797), R Guy Reeves, Fiammetta Santucci (185795), Santucci, Fiammetta, Reed, Floyd A., Jai A. Denton (185794), Lehane, Michael J., Jarosław Bryk (47108), Reeves, R. Guy, Jai A Denton, Reeves, R., Denton, J., Bryk, J.   +20 more
core   +1 more source

Risk assessment considerations for RNAi‐based genetically modified plants

EFSA Journal
The risk assessment (RA) requirements for genetically modified plants (GMPs) are defined in Regulation (EU) No 503/2013 and the EFSA guidance on the RA of food and feed from GM plants (EFSA GMO Panel, 2011). When a GMP is developed to silence transcripts
European Food Safety Authority (EFSA), Francisco Barro, Albert Braeuning, Tilemachos Goumperis, Aleksandra Lewandowska, Simon Moxon, Nikoletta Papadopoulou, Elena Sánchez‐Brunete   +7 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Guidance on selection of comparators for the risk assessment of genetically modified plants and derived food and feed

, 2011
This opinion provides guidance in the area of comparators taking into account the requirements for the molecular characterisation, the food and feed and the environmental risk assessments.
EFSA Panel on Genetically Modified Organisms (GMO)
core   +1 more source