Results 121 to 130 of about 434,975 (287)

Therapeutic Survey of Wild Medicinal Flora of Soan River, Rawalpindi, Pakistan [PDF]

, 2016
Medicinal plants have are worth for human civilizations for treating syndromes. The current study was conducted to document the unexplored medicinal flora of Soan River, Rawalpindi.
Ahmad, S. S. (Shiekh), Bashir, H. (Hafsa)   +1 more
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Cytotoxicity and Antioxidant Activity of Five Plant Species of Solanaceae Family from Iran

Journal of Medicinal Plants, 2012
Background: The use of natural products as anticancer and antioxidant agents has a long history. Several drugs currently used in chemotherapy were isolated from plant species.
F Khalighi-Sigaroodi, M Ahvazi, D Yazdani, M Kashefi   +3 more
doaj  

Improvement of seed quality of medicinal plants and herbs in organic farming [PDF]

, 2006
As in vegetable growing or grain cropping the seed quality is an important factor for the successful cultivation of medicinal plants and herbs. In spite of intensive efforts made by specialised seed producers there are recurring problems with important ...
Aedtner, Ina, Blum, Hanna, Fausten, Gudrun, Gaerber, Ute, Jahn, Marga, Nega, Eva   +5 more
core  

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Phytochemical and Morphophysiological Responses of Dill (Anethum graveolens L.) to Foliar Application of Potassium Sulfate and Methanol Biostimulant

Journal of Medicinal Plants, 2017
Background: The application of methanol biostimulant and potassium sulfate with reducing of photorespiration and transpiration in C3 plants, increasing the absorption of water and food, and biosynthesis of amino acids can have a direct or indirect effect
A Mehrafarin, HA Naghdi Badi, M Mirzai Motlagh, M Salehi, M Ghiasi Yekta   +4 more
doaj  

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

A review of the genus Caesalpinia L.: emphasis on the cassane and norcassane compounds and cytotoxicity effects

Journal of Medicinal Plants, 2020
Background: Many herbal remedies have been used in medical systems for the cure of diseases. One of these important applications is usage of them as cytotoxic agents for the treatment of cancers and tumors.
Narges Pournaghi, Farahnaz Khalighi-Sigaroodi, Elahe Safari, Reza Hajiaghaee   +3 more
doaj  

Marketing of Medicinal Plants of Utror-Gabral Valleys, Swat, Pakistan [PDF]

, 2003
This paper is based on the results of an ethnobotanical project carried out in the area comprising Utror-Gabral Valleys of upper Swat. The residents of the area use indigenous medicinal plants for curing diseases and also sell some of them in the local ...
Begum, Shaheen, Hamayun, Muhammad, Khan, Mir Ajab   +2 more
core   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source