Results 131 to 140 of about 450,484 (298)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Eksplorasi Tumbuhan Obat Pada Ketinggian 1400-1600 m. Dpl Di Kawasan Hutan Alam Girimanik Setren Kecamatan Slogohimo Wonogiri [PDF]

open access: yes, 2016
Natural Forest Girimanik one of the forests have flora diversity including medicinal plants. The purpose of this study was to determine the species of medicinal plants at an altitude of 1400-1600 asl. in the Natural Forest district Girimanik.
ANNOFI KUSUMA, NELA   +1 more
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Hypotensive medicinal plants according to ethnobotanical evidence of Iran: A systematic review [PDF]

open access: yes, 2016
Hypertension is called the silent killer because it leads finally to death silently and asymptomatically. If hypertension is not controlled at early stages, it disturbs the functions of cardiovascular system and other organs of the body.
Asadi-Samani, Majid.   +2 more
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Cytotoxicity and Antioxidant Activity of Five Plant Species of Solanaceae Family from Iran

open access: yesJournal of Medicinal Plants, 2012
Background: The use of natural products as anticancer and antioxidant agents has a long history. Several drugs currently used in chemotherapy were isolated from plant species.
F Khalighi-Sigaroodi   +3 more
doaj  

A review of the genus Caesalpinia L.: emphasis on the cassane and norcassane compounds and cytotoxicity effects

open access: yesJournal of Medicinal Plants, 2020
Background: Many herbal remedies have been used in medical systems for the cure of diseases. One of these important applications is usage of them as cytotoxic agents for the treatment of cancers and tumors.
Narges Pournaghi   +3 more
doaj  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Phytochemical and Morphophysiological Responses of Dill (Anethum graveolens L.) to Foliar Application of Potassium Sulfate and Methanol Biostimulant

open access: yesJournal of Medicinal Plants, 2017
Background: The application of methanol biostimulant and potassium sulfate with reducing of photorespiration and transpiration in C3 plants, increasing the absorption of water and food, and biosynthesis of amino acids can have a direct or indirect effect
A Mehrafarin   +4 more
doaj  

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