Results 131 to 140 of about 205,606 (312)

Medicinal plants of South Asia : novel sources for drug discovery /

Medicinal Plants of South Asia: Novel Sources for Drug Discovery provides a comprehensive review of medicinal plants of this region, highlighting chemical components of high potential and applying the latest technology to reveal the underlying chemistry ...
Hanif, Muhammad Asif,editor.
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Medicinal resources of the Miombo woodlands of Urumwa, Tanzania: Plants and its uses

, 2011
Journal of Medicinal Plants Research 2011: Vol. 5(27), pp. 6352-6372A study was done to document different plants and their use for primary health care by communities around the Miombo woodland of Urumwa, Tanzania.
Augustino, S., Hall, J. B., Makonda, F. B. S., Ishengoma, R. C.   +3 more
core   +2 more sources

Primary Active Seed Substances from Medicinal Plants as a Possible Supplement to Livestock Nutrition [PDF]

, 2015
Some of the active substances from the seeds of medicinal plants have a beneficial effect on human and animal health. The representatives of this group of plants, in addition to the secondary (biologically) active substances significant for their ...
Miletic, A, Glamoclija, Dj, Ugrenovic, V, Jugovic, M, Filipovic, V, Popovic, V, Markovic, T   +6 more
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Investigation of Essential Oil and Citral Content, and Morpho-physiological Changes of Lippia citriodora in Response to Induction of Bioactive Compounds and Plant Growth Regulators

Journal of Medicinal Plants, 2017
Background: Lippia citriodora H.B.K is an important medicinal and aromatic plant from the Verbenaceae family. Objective: The aim of this study was to investigation of essential oil percentage, E-citral (geranial) content and morphophysiological changes ...
M Roodbaraky, A Mehrafarin, F Khalighi-Sigaroodi, HA Naghdi Badi   +3 more
doaj  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Study on Chemical Composition and Antimicrobial Activity of the Essential Oil of Thymus trautvetteri Klokov & Desj. – Shost.

Journal of Medicinal Plants, 2007
Background: The genus Thymus belongs to Lamiaceae family. This genus is comprised of about 350 species widespread in the world. 14 species exist in Iran of which four are endemic.
S Shahnazi, F Khalighi-Sigaroodi, Y Ajani, D Yazdani, M Ahvazi, R Taghizad-Farid   +5 more
doaj