Results 111 to 120 of about 143,458 (285)

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

Plaque regression and plaque stabilisation in cardiovascular diseases

Indian Journal of Endocrinology and Metabolism, 2013
Atherosclerosis is characterized by formation of plaques on the inner walls of arteries that threatens to become the leading cause of death worldwide via its sequelae of myocardial infarction and stroke.
Tarun Dave, J Ezhilan, Hardik Vasnawala, Vinod Somani   +3 more
doaj   +1 more source

Femoral Artery Atherosclerosis Is Associated With Physical Function Across the Spectrum of the Ankle-Brachial Index: The San Diego Population Study. [PDF]

, 2017
BackgroundThe ankle-brachial index (ABI) is inadequate to detect early-stage atherosclerotic disease, when interventions to prevent functional decline may be the most effective.
Allison, Matthew A, Barinas-Mitchell, Emma, Criqui, Michael H, Denenberg, Julie O, Ellis, Alicia M, Forbang, Nketi I, Ix, Joachim H, Jenny, Nancy S, Marasco, Antoinette M, McQuaide, Belinda J, Rifkin, Dena E, Suder, Natalie C, Wassel, Christina L   +12 more
core   +1 more source

Effect Differences of Omega‐3 Fatty Acids From Plant Oil and Fish Oil on Human Health

AgriFood: Journal of Agricultural Products for Food, EarlyView.
Omega‐3 fatty acids in plant oil is no less than fish oil on human health. ALA in plant oil takes directly healthy effects without conversion to DHA and EPA. Plant oil can be substitutes for fish oil to support partial ω‐3 fatty acids. For people who cannot afford fish oil, plant oil is also good for public health.
Mengxue Fang, Chunyan Xiang, Liangxiao Zhang, Peiwu Li   +3 more
wiley   +1 more source

Relationship between the Levels of MMP-9, TIMP-1, and Zinc in Biological Samples of Patients with Carotid Atherosclerosis [PDF]

International Journal of Biomedicine, 2015
The aim our study was to evaluate the levels of zinc in blood serum, hair, and specimens of carotid artery atherosclerotic plaques (CAAPs) and their relationship to levels of MMP-9 and TIMP-1 in the serum of patients with stable and unstable CAAPs ...
Zakhro A. Usmanova
doaj  

Synthetic Electrocardiogram Spectrogram Generation Using Generative Adversarial Network‐Based Models: A Comparative Study

Advanced Intelligent Systems, EarlyView.
Cardiovascular diseases are leading death causes; electrocardiogram (ECG) analysis is slow, motivating machine learning and deep learning. This study compares deep convolutional generative adversarial network, conditional GAN, and Wasserstein GAN with gradient penalty (WGAN‐GP) for synthetic ECG spectrograms; Fréchet Inception Distance (FID) and ...
Giovanny Barbosa‐Casanova, Norelli Schettini, Winston Percybrooks, Begoña García‐Zapirain   +3 more
wiley   +1 more source

Coronary Artery Disease and Atherosclerosis in Other Vascular Districts: Epidemiology, Risk Factors and Atherosclerotic Plaque Features

Life
Coronary artery disease (CAD) is the main cause of morbidity and death worldwide, and atherosclerosis represents the leading pathophysiological pathway responsible for CAD.
Michele Russo, Filippo Luca Gurgoglione, Alessandro Russo, Riccardo Rinaldi, Laura Torlai Triglia, Matteo Foschi, Carlo Vigna, Rocco Vergallo, Rocco Antonio Montone, Umberto Benedetto, Giampaolo Niccoli, Marco Zimarino   +11 more
doaj   +1 more source

The complexity of dementia development and its comorbidities: The collaborative cross‐mouse population for multivarious tasks approach

Animal Models and Experimental Medicine, EarlyView.
The increasing prevalence of dementia and related neurodegenerative diseases—including Alzheimer's disease, Parkinson's disease, multiple sclerosis, and amyotrophic lateral sclerosis—poses a growing public health challenge. These conditions have traditionally been studied as isolated central nervous system disorders, but emerging evidence points to ...
Osayd Zohud, Iqbal M. Lone, Kareem Midlej, Fuad A. Iraqi   +3 more
wiley   +1 more source

Up-regulated expression of NHE1 and Netrin-1 in atherosclerotic plaque of ApoE-/-mice [PDF]

Jichu yixue yu linchuang, 2020
Objective To investigate whether ApoE-/- mouse atherosclerotic plaque tissue and RAW 264.7 simultaneously express sodium hydrogen exchanger 1 (NHE1) and neurite guidance factor-1 (netrin-1), and their co-localization and interaction.
YANG Hui, MO Xian-gang, WANG Lan, ZHANG Shi-yue
doaj  

DNase1 RS1053874 Polymorphism is Associated with Early Neurological Recovery through NET Modulation and with Long‐Term Survival in Ischemic Stroke: A Prospective Cohort Study

Annals of Neurology, EarlyView.
Objective Immunothrombosis contributes to ischemic stroke pathophysiology through neutrophil extracellular trap (NET) formation, which promotes thrombus stabilization and microvascular dysfunction. DNase1 is the principal endonuclease responsible for NET degradation.
B. Díaz‐Benito, P. Calleja, L. Alzamora, A. Ruiz‐García, A. Martínez‐Salio, M. Muñoz‐García, F. Ostos, A. García‐Culebras, A. Moraga, M.A. Moro, I. Lizasoain   +10 more
wiley   +1 more source