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Imaging the carotid atherosclerotic plaque [PDF]
This mini review provides a concise overview of imaging techniques that are currently used to image the atheroscletoric plaque in the carotid artery in vivo. The main techniques include ultrasound imaging, X-ray imaging, magnetic resonance imaging and positron emission tomography imaging.
Elena Giulia Milano+5 more
openaire +3 more sources
Research Progress on the Risk Factors and Outcomes of Human Carotid Atherosclerotic Plaques
Objective: Atherosclerosis is an inflammatory process that results in complex lesions or plaques that protrude into the arterial lumen. Carotid atherosclerotic plaque rupture, with distal atheromatous debris embolization, causes cerebrovascular events ...
Xiang-Dong Xiong+3 more
doaj +1 more source
Atherosclerotic plaque vulnerability and rupture increase the risk of acute coronary syndromes. Advanced lesion macrophage apoptosis plays important role in the rupture of atherosclerotic plaque, and endoplasmic reticulum stress (ERS) has been proved to ...
Jin-Ling Ren+9 more
doaj +1 more source
Atherosclerotic plaque near the carotid sinus is a key risk factor for ischemic stroke. Although disturbed hemodynamic environments around atherosclerotic plaque had been investigated in many studies, the effect of their symmetrical features, especially ...
Xianghui Gong+5 more
doaj +1 more source
Atherosclerotic carotid plaque composition: a 3T and 7T MRI-histology correlation study [PDF]
Background and Purpose Carotid artery atherosclerotic plaque composition may influence plaque stability and risk of thromboembolic events, and non-invasive plaque imaging may therefore permit risk stratification for clinical management.
Condon, B.+7 more
core +1 more source
Npp1 promotes atherosclerosis in ApoE knockout mice. [PDF]
Ecto-nucleotide pyrophosphatase/phosphodiesterase 1 (NPP1) generates inorganic pyrophosphate (PP(i)), a physiologic inhibitor of hydroxyapatite deposition.
Nitschke, Yvonne+3 more
core +1 more source
Exploration of the atherosclerotic plaque
During the past 3 decades we have achieved a better understanding of the atherosclerotic process. It has been described as a series of changes in the intima of arteries consisting of the focal accumulation of lipids, complex carbohydrates, blood and blood products, fibrous tissues, and calcium that are also associated with changes in the media.
John H. Ip, V Fuster, JH Chesebro
openaire +3 more sources
Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis [PDF]
Macrophages specialize in removing lipids and debris present in the atherosclerotic plaque. However, plaque progression renders macrophages unable to degrade exogenous atherogenic material and endogenous cargo including dysfunctional proteins and ...
Ali, Sahl+19 more
core +2 more sources
Orthopedic surgery increases atherosclerotic lesions and necrotic core area in ApoE-/- mice [PDF]
Background and aims Observational studies show a peak incidence of cardiovascular events after major surgery. For example, the risk of myocardial infarction increases 25-fold early after hip replacement.
Chen+39 more
core +1 more source
Atherosclerosis is an important cause of cerebrovascular and cardiovascular disease (CVD). Lipid infiltration, inflammation, and altered vascular stress are the critical mechanisms that cause atherosclerotic plaque formation.
Zhiwei He+6 more
doaj +1 more source