An integrated approach to simulating the vulnerable atherosclerotic plaque [PDF]
arXiv, 2019 Analyses of individual atherosclerotic plaques are mostly descriptive, relying -- for example -- on histological classification by spectral analysis of ultrasound waves or staining and observing particular cellular components. Such passive methods have proved useful for characterizing the structure and vulnerability of plaques but have little ...
arxiv
ATHEROSCLEROTIC PLAQUE OF RENAL VASA RECTA ON PATIENT WITH CALCIUM STONE
Jurnal Urologi Indonesia, 2013 Objective: We would like to identify whether atherosclerotic plaque inside renal vasa recta correlates with the formation of calcium stone. Material & Method: Samples are taken from kidney tissue removed by nephrectomy due to stone and non-stone disease.
Sawkar Vijay Pramod +3 more
doaj +1 more source
What Is the Added Value of Carotid CEUS in the Characterization of Atherosclerotic Plaque?
MedicinaBackground and Objectives: Unstable atherosclerotic plaque in the arteries is one of the main risk factors for cerebral ischemia. Duplex ultrasound is a frequently used diagnostic method, but it has some limitations for microvascularization and ...
Andrejs Lioznovs +4 more
doaj +1 more source
Myeloid cell-specific Irf5 deficiency stabilizes atherosclerotic plaques in Apoe–/– mice
Molecular Metabolism, 2021 Objective: Interferon regulatory factor (IRF) 5 is a transcription factor known for promoting M1 type macrophage polarization in vitro. Given the central role of inflammatory macrophages in promoting atherosclerotic plaque progression, we hypothesize ...
Julia Leipner +17 more
doaj
Relationship between the Levels of MMP-9, TIMP-1, and Zinc in Biological Samples of Patients with Carotid Atherosclerosis [PDF]
International Journal of Biomedicine, 2015 The aim our study was to evaluate the levels of zinc in blood serum, hair, and specimens of carotid artery atherosclerotic plaques (CAAPs) and their relationship to levels of MMP-9 and TIMP-1 in the serum of patients with stable and unstable CAAPs ...
Zakhro A. Usmanova
doaj
A Two-Phase Model of Early Fibrous Cap Formation in Atherosclerosis [PDF]
arXiv, 2018 Atherosclerotic plaque growth is characterised by chronic inflammation that promotes accumulation of cellular debris and extracellular fat in the inner artery wall. This material is highly thrombogenic, and plaque rupture can lead to the formation of blood clots that occlude major arteries and cause myocardial infarction or stroke. In advanced plaques,
arxiv
Segmentation of Soft atherosclerotic plaques using active contour models [PDF]
arXiv, 2016 Detection of non-calcified plaques in the coronary tree is a challenging problem due to the nature of comprising substances. Hard plaques are easily discernible in CTA data cloud due to apparent bright behaviour, therefore many approaches have been proposed for automatic segmentation of calcified plaques.
arxiv
A mathematical model for smooth muscle cell phenotype switching in atherosclerotic plaque [PDF]
arXivSmooth muscle cells (SMCs) play a fundamental role in the development of atherosclerotic plaques. SMCs may ingest lipids in a similar way to monocyte-derived macrophages (MDMs) in the plaque. This can stimulate SMCs to undergo a phenotypic switch towards a macrophage-like phenotype.
arxiv
Up-regulated expression of NHE1 and Netrin-1 in atherosclerotic plaque of ApoE-/-mice [PDF]
Jichu yixue yu linchuang, 2020 Objective To investigate whether ApoE-/- mouse atherosclerotic plaque tissue and RAW 264.7 simultaneously express sodium hydrogen exchanger 1 (NHE1) and neurite guidance factor-1 (netrin-1), and their co-localization and interaction.
YANG Hui, MO Xian-gang, WANG Lan, ZHANG Shi-yue
doaj
A Multiphase Model of Growth Factor-Regulated Atherosclerotic Cap Formation [PDF]
arXiv, 2019 Atherosclerosis is characterised by the growth of fatty plaques in the inner (intimal) layer of the artery wall. In mature plaques, vascular smooth muscle cells (SMCs) are recruited from the adjacent medial layer to deposit a cap of fibrous collagen over the fatty plaque core.
arxiv