Results 211 to 220 of about 230,221 (297)

Drug‐coated balloons: From conventional designs to next‐generation innovations in vascular therapy

BMEMat, EarlyView.
This review traces the evolution of drug‐coated balloons (DCBs) from conventional designs to next‐generation platforms. We highlight innovations in balloon engineering, coating technologies, and therapeutic agents that enhance localized drug delivery while addressing challenges in efficiency, safety, and biocompatibility for vascular and emerging non ...
Lu Zhang, Jiawei Cui, Jin Wang, Manfred F. Maitz, Rifang Luo, Yunbing Wang   +5 more
wiley   +1 more source

A weakly supervised framework for automated biological assay assessment. [PDF]

Virus Res
Jiang H, Guo Q, Zhi X, Li H, Chen Y.
europepmc   +1 more source

Atomically precise metal cluster enzymes for pathological tissue regeneration

BMEMat, EarlyView.
Schematic illustration of atomically precise metal cluster enzymes (MCEs) for pathological tissue regeneration. Atomically precise MCEs can modulate biological processes, such as attenuation of inflammatory responses, eradication of bacterial pathogens, regulation of angiogenesis, and promotion of cell development.
Ziqiang Xiong, Zhifeng Shi, Mengqing Li, Jien Han, Haoyan Chen, Maofei Ran, Shaojian Zhong, Limin Ma, Chengyun Ning, Youzhun Fan, Zhenghua Tang, Peng Yu   +11 more
wiley   +1 more source

Repurposing FDA-approved drugs as multi-target neuroprotective agents for Alzheimer's disease via computational screening and experimental validation. [PDF]

Sci Rep
Phemphunananchai K, Waiwut P, Phetcharaburanin J, Poonsawas P, Boonyarat C.   +4 more
europepmc   +1 more source

Aβ34 is a BACE1-derived degradation intermediate associated with amyloid clearance and Alzheimer’s disease progression [PDF]

, 2019
Bateman, Randall J.
core   +1 more source

The power of many: when genetics met yeasts and high‐throughput

Biological Reviews, EarlyView.
ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley   +1 more source

Characterization of the Cross-Resistance of SARS-CoV‑2 Main Protease Inhibitors, Ibuzatrelvir, Ensitrelvir, and Nirmatrelvir. [PDF]

ACS Pharmacol Transl Sci
Tan H, Chi X, Deng X, Wang J.
europepmc   +1 more source

Design of experiments‐guided membrane capture facilitates integration of continuous virus inactivation using Phi6 as a surrogate virus in an intensified downstream process

Biotechnology Progress, EarlyView.
Abstract The growing demand for cost‐efficient and flexible biomanufacturing has increased interest in process‐intensified downstream platforms. This study evaluates an intensified monoclonal antibody (mAb) purification sequence, where two unit operations traditionally performed in batch mode—Protein A capture and low pH virus inactivation (VI)—are ...
Mario Grünberg, Lisa Lipski, Gabriel Fisicaro, Thomas Duvignau, Karolina Meyer‐Heinrichs, Diana Carmen Mocsy, Thomas‐Josef Filz, Bastian Quaas, Alexandra Stützer   +8 more
wiley   +1 more source

Broad-spectrum antiviral activity of the synthetic rocaglate zotatifin against Mayaro virus and other viruses. [PDF]

Front Cell Infect Microbiol
Valdés-Torres P, Campos D, Galán-Jurado PE, Zegarra D, Tuñon-Lorenzo I, González-Castillo F, Blanquer M, Mewa JC, Rivas C, González-Santamaría J.   +9 more
europepmc   +1 more source

A paraoxonase gene polymorphism, PON 1 (55), as an independent risk factor for increased carotid intima-media tickness in middle-aged women. [PDF]

, 2003
DE MICHELE M, FORTUNATO G, IANNUZZI A, MAZZACCARA, CRISTINA, PANICO, SALVATORE, RUBBA, PAOLO OSVALDO FEDERICO, SACCHETTI L., SALVATORE F, TINTO, NADIA, TRONO D, VITALE DF   +10 more
core