Results 51 to 60 of about 693,396 (299)

Single-Cell RNA Sequencing of Peripheral Blood Mononuclear Cells From Acute Myocardial Infarction

Frontiers in Immunology, 2022
BackgroundAcute myocardial infarction (AMI) can occur in patients with atherosclerotic disease, with or without plaque rupture. Previous studies have indicated a set of immune responses to plaque rupture.
Jun Qian, Yanhua Gao, Yan Lai, Zi Ye, Yian Yao, Keke Ding, Jing Tong, Hao Lin, Guoqi Zhu, Yunan Yu, Haoran Ding, Deqiang Yuan, Jiapeng Chu, Fei Chen, Xuebo Liu   +14 more
doaj   +1 more source

Association between apolipoprotein B/A1 ratio and coronary plaque vulnerability in patients with atherosclerotic cardiovascular disease: an intravascular optical coherence tomography study

Cardiovascular Diabetology, 2021
Background Apolipoprotein (Apo) A1 and Apo B are strongly associated with the risk of atherosclerotic cardiovascular disease (ASCVD). However, the relationship between the Apo B/A1 ratio and the morphology of coronary vulnerable plaques has not been ...
Fuxue Deng, Danni Li, Lei Lei, Qiang Yang, Qing Li, Hongtao Wang, Jie Deng, Qiangsun Zheng, Wei Jiang   +8 more
doaj   +1 more source

Case Report: ST-Elevation Myocardial Infarction Secondary to Acute Atherothrombotic Occlusion Treated With No Stent Strategy

Frontiers in Cardiovascular Medicine, 2022
BackgroundIntravascular imaging plays a vital role in the pathophysiology-based diagnosis and treatment of patients with ST-elevation myocardial infarction (STEMI).
Rahul Dhawan, Saurabhi Samant, Ganesh Gajanan, Yiannis S. Chatzizisis   +3 more
doaj   +1 more source

Coronary Plaque Characteristics and Underlying Mechanism of Acute Coronary Syndromes in Different Age Groups of Patients With Diabetes

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background High cardiovascular mortality has been reported in young patients with diabetes. However, the underlying pathology in different age groups of patients with diabetes has not been studied.
Keishi Suzuki, Takayuki Niida, Haruhito Yuki, Daisuke Kinoshita, Daichi Fujimoto, Hang Lee, Iris McNulty, Masamichi Takano, Sunao Nakamura, Tsunekazu Kakuta, Kyoichi Mizuno, Ik‐Kyung Jang   +11 more
doaj   +1 more source

Prevalence, Features, and Prognosis of Artery‐to‐Artery Embolic ST‐Segment–Elevation Myocardial Infarction: An Optical Coherence Tomography Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background The major underlying mechanisms contributing to acute coronary syndrome are plaque rupture, plaque erosion, and calcified nodule. Artery‐to‐artery embolic myocardial infarction (AAEMI) was defined as ST‐segment–elevation myocardial infarction ...
Masahiro Takahata, Yasushi Ino, Takashi Kubo, Takashi Tanimoto, Akira Taruya, Kosei Terada, Hiroki Emori, Daisuke Higashioka, Yosuke Katayama, Amir Kh. M. Khalifa, Teruaki Wada, Yuichi Ozaki, Kunihiro Shimamura, Yasutsugu Shiono, Manabu Kashiwagi, Akio Kuroi, Suwako Fujita, Atsushi Tanaka, Takeshi Hozumi, Takashi Akasaka   +19 more
doaj   +1 more source

Optical coherence tomography-guided deferred stenting in acute coronary syndromes

Journal of Indian College of Cardiology, 2022
Acute coronary syndromes were thought to be due to plaque rupture with superimposed thrombus. With optical coherence tomography plaque erosion (PE) can be detected in one third of cases. In young patients without major risk factors one can suspect PE. We
Immaneni Sathyamurthy, Srinivasan Narayanamoorthy Kanthallu, Vinodh Kumar Paulpandi   +2 more
doaj   +1 more source

Focal Geometry and Characteristics of Erosion-Prone Coronary Plaques in vivo Angiography and Optical Coherence Tomography Study

Frontiers in Cardiovascular Medicine, 2021
Objective: This study compared focal geometry and characteristics of culprit plaque erosion (PE) vs. non-culprit plaques in ST-segment elevated myocardial infarction (STEMI) patients in whom optical coherence tomography (OCT) identified PE as the cause ...
Muhua Cao, Muhua Cao, Tianyu Wu, Tianyu Wu, Jiawei Zhao, Jiawei Zhao, Zhuo Du, Zhuo Du, Zhuozhong Wang, Zhuozhong Wang, Lulu Li, Lulu Li, Guo Wei, Guo Wei, Jinwei Tian, Jinwei Tian, Haibo Jia, Haibo Jia, Gary S. Mintz, Bo Yu, Bo Yu   +20 more
doaj   +1 more source

The Applications of Single-Cell RNA Sequencing in Atherosclerotic Disease

Frontiers in Cardiovascular Medicine, 2022
Atherosclerosis still is the primary cause of death worldwide. Our characterization of the atherosclerotic lesion is mainly rooted in definitions based on pathological descriptions.
Lotte Slenders, Daniëlle E. Tessels, Sander W. van der Laan, Gerard Pasterkamp, Michal Mokry, Michal Mokry   +5 more
doaj   +1 more source

Cellular crosstalk in atherosclerotic plaque microenvironment

Cell Communication and Signaling, 2023
Atherosclerosis is an underlying pathology of many vascular diseases as a result of cellular, structural and molecular dysfunctions within the sub-endothelial space.
Elmira Mahdinia, Nafiseh Shokri, Abdolkarim Talebi Taheri, Sahar Asgharzadeh, Mohammad Elahimanesh, Mohammad Najafi   +5 more
doaj   +1 more source

Immune Mechanisms of Plaque Instability

Frontiers in Cardiovascular Medicine, 2022
Inflammation crucially drives atherosclerosis from disease initiation to the emergence of clinical complications. Targeting pivotal inflammatory pathways without compromising the host defense could compliment therapy with lipid-lowering agents, anti ...
Teresa Gerhardt, Teresa Gerhardt, Teresa Gerhardt, Arash Haghikia, Arash Haghikia, Arash Haghikia, Philip Stapmanns, David Manuel Leistner, David Manuel Leistner, David Manuel Leistner   +9 more
doaj   +1 more source