Results 91 to 100 of about 39,266 (270)
JEADV Clinical Practice, EarlyView.ABSTRACT Acute generalised exanthematous pustulosis (AGEP) is a rare, acute neutrophilic dermatosis most commonly triggered by drugs, which typically resolves within 2 weeks following withdrawal of the causative agent. Topical and systemic corticosteroids remain the standard treatment.
Alexandra Junge +5 more
wiley +1 more source
Systemic Absorption and Pharmacokinetics of Five Novel Topical Dermatologic Agents: A Review
JEADV Clinical Practice, EarlyView.ABSTRACT In recent years, innovative topical medications with novel mechanisms of action have emerged to treat common dermatologic conditions such as acne, atopic dermatitis, vitiligo, and actinic keratoses. These molecularly targeted therapies offer improved safety and tolerability compared to traditional options like corticosteroids.
Mary Dyson +4 more
wiley +1 more source
Approach to Nail Pitting in Pediatric and Adolescent Patients: A Dermatology Perspective
JEADV Clinical Practice, EarlyView.ABSTRACT This narrative review aims to discuss the etiologies of nail pitting in pediatric and adolescent patients, while providing a framework for further evaluation of possible underlying systemic conditions and their clinical findings from a dermatologic standpoint.
Elizabeth Botto +3 more
wiley +1 more source
Clinical, Cosmetic and Investigational DermatologyFan Jiang, Lingyi Lu, Sihan Wang, Feng Yuan, Lu Cao, Suling Xu,* Bingjiang Lin* Department of Dermatology, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang; National Clinical Medical Research Center for Skin and Immune ...
Jiang F +6 more
doaj
Trials, 2019 Background Psoriasis is a chronic, immune-mediated disorder with chronic plaque psoriasis being the primary manifestation during the remission stage. Patients often have a slow course and long history of the disease. The refractory type of psoriasis is a
Zhaoxia Chen +14 more
doaj +1 more source
Secukinumab: a new treatment option for psoriatic arthritis [PDF]
, 2016 Introduction: Psoriatic arthritis (PsA) is an immune-mediated chronic inflammatory arthropathy associated with impaired physical function and reduced quality of life.
McInnes, Iain B., Mease, Philip
core +1 more source
Ustekinumab for the treatment of psoriatic arthritis: an update. [PDF]
, 2014 Psoriatic arthritis occurs in 30% of psoriasis patients, and the treatment can be challenging in some patients. Recently, the US Food and Drug Administration approved ustekinumab, a fully human monoclonal antibody, for the management of psoriatic ...
Davari, Parastoo +3 more
core +1 more source
Psychodermatology of the Female: Hormones, Skin and Mental Health Across the Lifespan
JEADV Clinical Practice, EarlyView.Hormonal transitions across the female lifespan shape skin disease and psychiatric comorbidity through the brain–skin axis and Neuro‐Immuno‐Cutaneous‐Endocrine (NICE) network. This narrative review links puberty, menstruation, pregnancy, postpartum and menopause to dermatologic and psychosocial outcomes.
Sheila Sharifi +4 more
wiley +1 more source
Psoriasis: Classical vs. Paradoxical. The Yin-Yang of TNF and Type I Interferon
Frontiers in Immunology, 2018 Chronic plaque psoriasis is a common debilitating skin disease. The identification of the pathogenic role of the TNF/IL-23/TH17 pathway has enabled the development of targeted therapies used in the clinic today. Particularly, TNF inhibitors have become a
Alessio Mylonas, Curdin Conrad
doaj +1 more source
Long-term safety and efficacy of secukinumab in paediatric severe plaque psoriasis: 236-week, Phase 3 trial results. [PDF]
J Eur Acad Dermatol VenereolIn this Phase III study, secukinumab demonstrated sustained efficacy and a favourable safety profile in paediatric patients with chronic severe plaque psoriasis over a treatment period of 236 weeks. Abstract Background Plaque psoriasis, a chronic inflammatory disease, affects up to 2.1% of the global paediatric population.
Kaszuba A +11 more
europepmc +2 more sources