Results 11 to 20 of about 39,266 (270)

Histological Stratification of Thick and Thin Plaque Psoriasis Explores Molecular Phenotypes with Clinical Implications. [PDF]

open access: yesPLoS ONE, 2015
Psoriasis, which presents as red, scaly patches on the body, is a common, autoimmune skin disease that affects 2 to 3 percent of the world population. To leverage recent molecular findings into the personalized treatment of psoriasis, we need a strategy ...
Jaehwan Kim   +6 more
doaj   +1 more source

Secukinumab in the treatment of psoriasis: patient selection and perspectives. [PDF]

open access: yes, 2018
Secukinumab is a human monoclonal antibody targeting IL-17A that has been approved for three indications: moderate-to-severe plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis.
Beck, Kristen M   +2 more
core   +1 more source

Disseminated eruptive giant mollusca contagiosa in an adult psoriasis patient during efalizumab therapy [PDF]

open access: yes, 2008
Molluscum contagiosum is a common viral skin infection in children with atopic diathesis and not rare in HIV patients. We report a 45-year-old psoriasis patient who developed eruptive mollusca contagiosa during an antipsoriatic treatment with efalizumab.
Alexander Vasilevic Kuznetsov   +7 more
core   +1 more source

Serum Concentration of 25-Hydroxy Vitamin D in Patients with Chronic Plaque Psoriasis: A case control study

open access: yesJournal of the Dow University of Health Sciences, 2020
Objective: To determine 25-hydroxy vitamin D levels in patients of chronic plaque psoriasis and to assess any relationship between vitamin D deficiency and other disease parameters.
Yousuf Abd Mallick, Ahsun Jiwani
doaj   +1 more source

Clinical and Genetic Risk Factors Associated with Psoriatic Arthritis among Patients with Psoriasis. [PDF]

open access: yes, 2018
IntroductionPsoriatic arthritis (PsA) is a chronic, inflammatory arthritis that affects an estimated 30% of patients with psoriasis. PsA is underdiagnosed in primary care and dermatology clinics due to a variety of reasons, including failure of ...
Ahn, Richard   +3 more
core   +3 more sources

Interleukin levels and non-alcoholic fatty liver disease in chronic plaque psoriasis: An analytical case control study

open access: yesIndian Journal of Dermatology, 2023
Background: Psoriasis is a chronic, immune mediated inflammatory condition of the skin and imbalance in inflammatory mediators could result in insulin resistance, metabolic syndrome and facilitate the occurrence and progression of Non-alcoholic fatty ...
Vidya Yadav   +5 more
doaj   +1 more source

T-cell modulation for the treatment of chronic plaque psoriasis with efalizumab (Raptiva (TM)): Mechanisms of action [PDF]

open access: yes, 2004
Psoriasis is a chronic, incurable, auto-immune disorder with cutaneous manifestations. New evidence on the central role of the immune system in the pathogenesis of psoriasis increasingly provides insight into pathogenic steps that can be modulated to ...
Caro, I.   +7 more
core   +1 more source

The efficacy and safety of tyrosine kinase 2 inhibitor deucravacitinib in the treatment of plaque psoriasis: a systematic review and meta-analysis of randomized controlled trials

open access: yesFrontiers in Medicine, 2023
BackgroundOrally effective therapeutics for plaque psoriasis with improved response rates, lower toxicity and costs are needed in clinical practices.
Jingyue Qiu   +5 more
doaj   +1 more source

Viewpoint on handling anti-TNF failure in psoriasis [PDF]

open access: yes, 2013
An association among the occurrence of antidrug antibodies (ADAs), diminished trough serum drug levels (TSDLs) and non-response or loss of response has been described for several tumor necrosis factor alpha (TNF) blocking agents in a variety of diseases,
BRACKE, STEFANIE, Lambert, Jo
core   +1 more source

Effectiveness of risankizumab in plaque psoriasis with involvement of difficult-to-treat areas: a real-world experience from two referral centers

open access: yesJournal of Dermatological Treatment, 2023
The management of plaque psoriasis that affects difficult-to-treat areas can be challenging. Biologics have become the treatment of choice for moderate-to-severe plaque psoriasis.
Diego Orsini   +10 more
doaj   +1 more source

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