Results 31 to 40 of about 39,266 (270)

Efficacy and safety of tofacitinib for the treatment of chronic plaque psoriasis: a systematic review and meta-analysis

Journal of International Medical Research, 2019
Background Tofacitinib is an oral Janus kinase (JAK) inhibitor that targets JAK1 and JAK3, and thus regulates immune response. Therefore, tofacitinib is used to treat immune-mediated inflammatory diseases such as chronic plaque psoriasis.
Fangyuan Tian, Zhaoyan Chen, Ting Xu
doaj   +1 more source

Randomised, double-blind, multicentre, phase Ⅰ/Ⅱ dose escalation and expansion trial of GR1501 in patients with plaque psoriasis: study protocol

BMJ Open, 2020
Introduction Psoriasis is a life-long, immune-mediated disease that greatly reduces the quality of life of patients. Plaque psoriasis is the most common form of psoriasis. Treatment options for plaque psoriasis with good tolerance and sufficient response
Qi Wang, Lin Cai, Qian Wang, Wenliang Dong, Xiaoyan Nie, Jiaxue Wang, Lin Xia, Weixing Fu, Tiantian Shen, Huaying Fan, Suping Niu, Yimin Cui, Qingshan Zheng, Jianzhong Zhang, Yi Fang   +14 more
doaj   +1 more source

Immune checkpoint inhibitor‐mediated psoriasis treated with biologics

JEADV Clinical Practice, 2023
Skin toxicities are the most prevalent immune‐related adverse events of immune checkpoint inhibitors (ICIs), but psoriasis is uncommon. To date, there are no treatment guidelines for this unique patient cohort.
Pei Ming Yeo, Nisha Suyien Chandran
doaj   +1 more source

JAK3 as an emerging target for topical treatment of inflammatory skin diseases [PDF]

, 2016
The recent interest and elucidation of the JAK/STAT signaling pathway created new targets for the treatment of inflammatory skin diseases (ISDs). JAK inhibitors in oral and topical formulations have shown beneficial results in psoriasis and alopecia ...
Alves de Medeiros, Ana, De Schepper, Sofie, Desmet, Eline, Lambert, Jo, Speeckaert, Reinhart, Van Gele, Mireille   +5 more
core   +2 more sources

Health-related quality of life in patients with palmoplantar pustulosis – a Swedish register study

Annals of Medicine
Background Real-world data on health-related quality of life (HRQoL) in palmoplantar pustulosis (PPP) are scarce and few studies have analysed the generic HRQoL.Objectives To assess HRQoL using the generic EQ-5D instrument and the Dermatology Life ...
Jenny M. Norlin, Sofia Löfvendahl, Marcus Schmitt-Egenolf   +2 more
doaj   +1 more source

Use of ustekinumab after other biological therapies in moderate-severe psoriasis: Real long-term data [PDF]

Farmacia Hospitalaria, 2020
Objective: Ustekinumab is used in moderate-severe plaque psoriasis with inadequate response to anti- tumour necrosis factor α drugs. Recent studies support the need to assess real long-term data.
Manuel David Gil-Sierra, Esmeralda Ríos-Sánchez, María del Pilar Briceño-Casado   +2 more
doaj   +1 more source

Treatment recommendations for psoriatic arthritis [PDF]

, 2008
Objective: To develop comprehensive recommendations for the treatment of the various clinical manifestations of psoriatic arthritis (PsA) based on evidence obtained from a systematic review of the literature and from consensus opinion.
Ritchlin, CT, Kavanaugh, A, Gladman, DD, Mease, PJ, Helliwell, P, Boehncke, W-H, de Vlam, K, Fiorentino, D, FitzGerald, O, Gottlieb, AB, McHugh, NJ, Nash, P, Qureshi, AA, Soriano, ER, Taylor, WJ, GRAPPA   +15 more
core   +1 more source

The Effect of Weight Loss in Obese Patients with Chronic Stable Plaque-Type Psoriasis

Dermatology Research and Practice, 2013
Background. Chronic plaque psoriasis is frequently associated with obesity. The effect of a low-calorie diet on psoriasis has not been investigated. Objective.
Wanjarus Roongpisuthipong, Marinya Pongpudpunth, Chulaporn Roongpisuthipong, Natta Rajatanavin   +3 more
doaj   +1 more source

Effect of low-calorie diet on psoriasis severity index, triglycerides, liver enzymes, and quality of life in psoriatic patients with non-alcoholic fatty liver disease

Rheumatology, 2023
Introduction Chronic-plaque psoriasis is a chronic inflammatory dermatological disease. Obesity comorbidities, including non-alcoholic fatty liver disease, are highly prevalent in patients with chronic-plaque psoriasis.
Ali Mohamed Ali Ismail, Ahmad Elsayed Saad, Ramy Salama Draz   +2 more
doaj   +1 more source

"TREATMENT OF CHRONIC PLAQUE TYPE PSORIASIS WITH SYSTEMIC MYCOPHENOLATE MOFETIL " [PDF]

Acta Medica Iranica, 2006
Chronic plaque-type psoriasis may be difficult to control without the use of potent systemic therapies that are accompanied by systemic toxicity. Mycophenolate mofetil is a novel agent that may be effective in the treatment of chronic plaque type ...
M. Akhyani, S. Toosi R. M. Robati   +1 more
doaj   +1 more source