Results 111 to 120 of about 16,802 (217)

Oral Phageome as Potential Modulators of Periodontal Dysbiosis. A Systematic Review

Oral Diseases, EarlyView.
ABSTRACT Introduction The oral phageome, comprising bacteriophages inhabiting the oral cavity, has been proposed as a potential modulator of periodontal health and disease. This systematic review synthesizes current evidence on interactions between bacteriophages, key periodontal bacteria, and the host in periodontitis.
Marco Bonilla, Sara El‐Amrani, Pablo Galindo‐Moreno, Francisco Mesa   +3 more
wiley   +1 more source

Evolution of the PRNT: Merging tradition and innovation to set the gold standard in the era of automation

Human Vaccines & Immunotherapeutics
The plaque reduction neutralization test (PRNT) is the gold standard for quantifying neutralizing antibodies owing to its high sensitivity and specificity.
Caio Denani, Ingrid Horbach, Bruno Setatino, Adriana Azevedo, Sheila Lima, Waleska Schwarcz, Ivanildo Sousa   +6 more
doaj   +1 more source

Periodontitis‐Associated Bacteria and Their Connection to Proinflammatory Biomarkers in Periodontal Pockets: A Clinical Microbiological Study

Oral Diseases, EarlyView.
ABSTRACT Background This study examines the relationship between the microbial load of selected periodontitis‐associated bacteria (PAB) and proinflammatory biomarkers in gingival crevicular fluid (GCF) from patients with periodontitis. Methods GCF and subgingival biofilm samples were collected from the deepest periodontal pocket of each quadrant of 515
Nils Werner, Charlotte Wetzel, Vinay Pitchika, Burkhard Summer, Christina Ern, Richard Heym, Thomas Spinell, Falk Schwendicke, Matthias Folwaczny, Caspar Victor Bumm   +9 more
wiley   +1 more source

Standardization, validation, and comparative evaluation of a convenient surrogate recombinant vesicular stomatitis virus plaque reduction test for quantification of Hantaan orthohantavirus (HTNV) neutralizing antibodies

Virology Journal
Hantaan orthohantavirus (HTNV) is responsible for severe hemorrhagic fever with renal syndrome (HFRS), which has a case fatality rate of 1% to 10%. Currently, the inactive vaccine licensed in endemic areas elicit low levels of neutralizing antibodies ...
Jing Wei, Hui Zhang, Jiawei Pei, Qiqi Yang, Yuan Wang, Xiaolei Jin, He Liu, Liang Zhang, Hongwei Ma, Linfeng Cheng, Yangchao Dong, Yingfeng Lei, Yinlan Bai, Zhikai Xu, Pengbo Yu, Fanglin Zhang, Wei Ye   +16 more
doaj   +1 more source

The oral microbiota and periodontal health in orthodontic patients

Periodontology 2000, EarlyView.
Abstract The oral microbiota develops within the first 2 years of childhood and becomes distinct from the parents by 4 years‐of‐age. The oral microbiota plays an important role in the overall health/symbiosis of the individual. Deviations from the state of symbiosis leads to dysbiosis and an increased risk of pathogenicity.
Brandon W. Peterson, Geerten‐Has Tjakkes, Anne‐Marie Renkema, David J. Manton, Yijin Ren   +4 more
wiley   +1 more source

Seroprevalence of measles antibodies and factors associated with susceptibility: a national survey in Mexico using a plaque reduction neutralization test. [PDF]

Sci Rep, 2020
Díaz-Ortega JL, Ferreira-Guerrero E, Cruz-Hervert LP, Delgado-Sánchez G, Ferreyra-Reyes L, Yanes-Lane M, Mongua-Rodríguez N, Montero-Campos R, Castañeda-Desales D, García-García L.   +9 more
europepmc   +1 more source

Genetic risk variants implicate impaired maintenance and repair of periodontal tissues as causal for periodontitis—A synthesis of recent findings

Periodontology 2000, EarlyView.
AbstractPeriodontitis is a complex inflammatory disease in which the host genome, in conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition is the strongest risk factor in the first decades of life. As people age, chronic exposure to the periodontal microbiome puts a strain on the proper maintenance of ...
Arne S. Schaefer, Luigi Nibali, Noha Zoheir, Niki M. Moutsopoulos, Bruno G. Loos   +4 more
wiley   +1 more source

Emerging locally delivered antimicrobial and immunomodulatory approaches for the prevention/treatment of peri‐implant diseases

Periodontology 2000, EarlyView.
Abstract Peri‐implant diseases are dysbiosis‐mediated inflammatory disorders that occur in susceptible hosts. Antimicrobials and immunomodulatory agents therefore might be pertinent as adjunctive measures in the treatment of such disorders. The aim of this narrative review was to examine the existing evidence and assess the effectiveness of emerging ...
Alberto Monje, Ettore Amerio, Irene Mallor, Conrado Aparicio   +3 more
wiley   +1 more source

Antibiotic‐mediated immune modulation in periodontitis

Periodontology 2000, EarlyView.
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez, R. M. Arce, Camila Pinheiro Furquim, Cristiane Gonçalves, Alpdogan Kantarci, Magda Feres, Nidia C. Castro dos Santos   +6 more
wiley   +1 more source

Novel and emerging antimicrobial strategies in the management of oral infections

Periodontology 2000, EarlyView.
Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley   +1 more source