Results 211 to 220 of about 29,718 (289)

Novel Wide‐Spectrum Virucidal Lipid Nanoparticles

open access: yesSmall, Volume 22, Issue 7, 2 February 2026.
POSTAN is a novel broad‐spectrum antiviral nanoparticle that combines safety with potent virucidal activity. Composed of biocompatible lipids, it mimics heparan sulfate proteoglycans and lipid rafts exploited by viruses, thereby dismantling viral envelopes and blocking replication.
Yugo Araújo Martins   +10 more
wiley   +1 more source

Bacterial Expression of Gene‐Encoding DNA Origami Structures

open access: yesSmall Structures, Volume 7, Issue 2, February 2026.
Bacterial targeting via programmable DNA origami, varying in rigidity and compactness is unexplored. In transformation assays, origami reduces transformation efficiency compared to single‐stranded scaffolds. Structural features and surface modifications, however, improve transformation outcomes.
Verena Dobretzberger   +7 more
wiley   +1 more source

Age and Sex Impact the Role of Thrombospondin‐2 and Thrombospondin‐5 in Response to Hindlimb Ischemia

open access: yesFASEB BioAdvances, Volume 8, Issue 2, February 2026.
In vitro: TSP‐2 inhibited angiogenesis in early passage ECs and disrupted tubules in late passage ECs. TSP‐5 prevented early passage tubule disruption. Late passage cells showed greater disruption than early passage. In vivo: TSP‐2 was anti‐angiogenic in young mice and anti‐arteriogenic in old mice; TSP‐5 had no effect on angiogenesis but largely ...
Ashley A. Peters   +6 more
wiley   +1 more source

Hydroxypropyl Cellulose Enhances Immune Responses to the Current Seasonal Influenza Vaccine in Mice

open access: yesMicrobiology and Immunology, Volume 70, Issue 2, Page 68-79, February 2026.
ABSTRACT Influenza A and B viruses cause annual epidemics and continue to pose global public health concerns. The most effective approach to preventing or mitigating the severity of influenza is vaccination. Inactivated split influenza HA vaccines are commonly used worldwide due to their strong safety profile and broad range of target groups; however ...
Nantaporn Kaewaroon   +4 more
wiley   +1 more source

The Redox Properties of Polyphenols and Their Role in ROS Generation for Biomedical Applications

open access: yesAngewandte Chemie, Volume 138, Issue 3, 16 January 2026.
The dual redox nature of polyphenols enables antioxidant activity and controlled reactive oxygen species (ROS) generation. This review details the biomedical applications of polyphenols in materials such as nanoparticles, coatings, and hydrogels for antimicrobial, tissue regeneration, and cancer therapies.
Jose Bolaños‐Cardet   +7 more
wiley   +2 more sources

Deficiency of Microglial‐Derived Spp1 Exacerbates Age‐Related Memory Decline by Impairing Mitochondrial Complex I Function

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
Microglia‐derived Spp1 regulates OXPHOS via the AKT/Complex I pathway to mitigate age‐related memory decline. (Graphical Abstract was created using BioRender). ABSTRACT Age‐related memory decline is a hallmark of brain aging and a primary risk factor for neurodegenerative disorders.
Meiling Wang   +9 more
wiley   +1 more source

Two-year persistence of MERS-CoV-specific antibody and T cell responses after MVA-MERS-S vaccination in healthy adults. [PDF]

open access: yesNat Commun
Mayer L   +17 more
europepmc   +1 more source

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