Results 41 to 50 of about 29,718 (289)
Development of a High-Content Orthopoxvirus Infectivity and Neutralization Assays. [PDF]
PLoS ONE, 2015 Currently, a number of assays measure Orthopoxvirus neutralization with serum from individuals, vaccinated against smallpox. In addition to the traditional plaque reduction neutralization test (PRNT), newer higher throughput assays are based on ...
Irina Gates +5 more
doaj +1 more source
Viruses, 2022 A robust serological test to measure neutralizing antibodies against SARS-CoV-2 in biosafety level-2 (BSL-2) laboratories is useful for monitoring antibody response after vaccination or natural infection.
Jing Zou +4 more
doaj +1 more source
International Journal of Infectious Diseases, 2023 Objectives: Regarding reactogenicity and immunogenicity, heterologous COVID-19 vaccination regimens are considered as an alternative to conventional immunization schemes.
Niko Kohmer +9 more
doaj +1 more source
An Integrated Research–Clinical BSL-2 Platform for a Live SARS-CoV-2 Neutralization Assay
Viruses, 2023 A reliable and efficient serological test is crucial for monitoring neutralizing antibodies against SARS-CoV-2 and its variants of concern (VOCs). Here, we present an integrated research–clinical platform for a live SARS-CoV-2 neutralization assay ...
Jing Zou +14 more
doaj +1 more source
SSRN Electronic Journal, 2022 Japanese encephalitis is prevalent throughout the temperate and tropical regions of Asia and is caused by the Japanese encephalitis virus (JEV), a mosquito-borne viral pathogen. The plaque reduction neutralization test (PRNT) is currently recommended as the gold standard test for detecting human antibodies against JEV.
Younhee, Park +11 more
openaire +3 more sources
Comparison of serological assays to titrate Hantaan and Seoul hantavirus-specific antibodies
Virology Journal, 2017 Background Hantaan and Seoul viruses, in the Hantavirus genus, are known to cause hemorrhagic fever with renal syndrome (HFRS). The plaque reduction neutralization test (PRNT), as conventional neutralization test for hantaviruses, is laborious and time ...
Weihong Li +9 more
doaj +1 more source
Viridot: An automated virus plaque (immunofocus) counter for the measurement of serological neutralizing responses with application to dengue virus. [PDF]
PLoS Neglected Tropical Diseases, 2018 The gold-standard method for quantifying neutralizing antibody responses to many viruses, including dengue virus (DENV), is the plaque reduction neutralization test (PRNT, also called the immunofocus reduction neutralization test).
Leah C Katzelnick +12 more
doaj +1 more source
A Plaque Reduction Neutralization Test for Human Cytomegalovirus.
Experimental Biology and Medicine, 1964 SummaryA plaque technique for human cytomegaloviruses has been developed employing human embryonic lung fibroblast cultures and an overlay containing 2% methyl cellulose. Neutralization tests employing the 80% plaque reduction endpoint were found to give reproducible results. Human adult sera exhibited titers of 1:8 to 1:64.
G, PLUMMER, M, BENYESH-MELNICK
openaire +2 more sources
Gamma interferon-dependent clearance of cytomegalovirus infection in salivary glands [PDF]
, 1992 Cytomegalovirus (CMV), similar to other members of the Herpesviridae family, can establish both persistent and latent infections. Each of the CMVs that are found in many animal species replicates in the salivary gland, and oral secretion represents a ...
Jonjic, Stipan +4 more
core +2 more sources
In vivo imaging of Zika virus reveals dynamics of viral invasion in immune-sheltered tissues and vertical propagation during pregnancy [PDF]
, 2020 Rationale: Zika virus (ZIKV) is a pathogenic virus known to cause a wide range of congenital abnormalities, including microcephaly, Guillain-Barre syndrome, meningoencephalitis, and other neurological complications, in humans. This study investigated the
Hu, Q +12 more
core +1 more source