Results 81 to 90 of about 16,802 (217)

Cross-neutralizing activity of the chikungunya vaccine VLA1553 against three prevalent chikungunya lineages

Emerging Microbes and Infections
Cross-neutralization is generally a prerequisite for cross-protection of vaccines against diseases caused by heterologous viruses. Using sera obtained from a randomized clinical phase 3 trial in adults, we investigated the cross-neutralization activity ...
Karin Kosulin, Trevor L. Brasel, Jeanon Smith, Maricela Torres, Annegret Bitzer, Katrin Dubischar, Vera Buerger, Robert Mader, Scott C. Weaver, David W.C. Beasley, Romana Hochreiter   +10 more
doaj   +1 more source

Plaque Reduction Neutralization Test for Smallpox Vaccines: Laboratory Optimization and Validation Method for Immunogenicity Assessment

Journal of Immunological Methods
The eradication of smallpox, a historic triumph in global public health, was accomplished without a complete conception of the mechanisms underlying vaccine-induced protection. Contemporary concerns regarding potential bioterrorism threats and the possibility of smallpox reemergence have spurred research efforts toward developing third-generation ...
Hyun-Jung, Kong, You-Jin, Kim, Dokeun, Kim, Yun-Ho, Hwang   +3 more
openaire   +2 more sources

Transgenic selection and underlying mechanisms in apicomplexan parasites

The FEBS Journal, EarlyView.
Transgenic selection markers have driven genetic engineering in apicomplexans, enabling precise, iterative experiments. This review discusses mechanistic details of drug selection markers, strategies for marker recycling, and practical considerations for several clinically relevant parasites.
Swaroop Peddiraju, Rakhee Lohia, Nishith Gupta   +2 more
wiley   +1 more source

Utility of an In-Vitro Micro-Neutralizing Test in Comparison to a Plaque Reduction Neutralization Test for Dengue Virus, Japanese Encephalitis Virus, and Zika Virus Serology and Drug Screening. [PDF]

Pathogens, 2023
Haga K, Chen ZN, Himeno M, Majima R, Moi ML.   +4 more
europepmc   +1 more source

Combating ageing beyond the cell: Emerging roles of extracellular proteostasis

The FEBS Journal, EarlyView.
Ageing challenges the body's ability to maintain a stable and functional proteome, leading to protein damage and aggregation both inside and outside cells. This review focuses on the less well understood mechanisms of extracellular protein quality control and how they become disrupted in ageing, particularly in neurodegenerative diseases.
Siddharth R. Venkatesh, Ivan Gallotta, Bolanle F. Olabiyi, Yoon Hee Choi, Sarah Inglesfield, Janet R. Kumita, Collin Y. Ewald, Della C. David   +7 more
wiley   +1 more source

The Complex World of Toothpaste Diversity, Meeting Patient Clinical Needs. An Umbrella Review

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Background Amidst numerous recent advancements in toothpaste formulations and active ingredients, some clinicians may believe all toothpastes are similar despite differences in their active ingredients and corresponding clinical application.
Jeanie Suvan, Crystal Marruganti
wiley   +1 more source

Evaluation of Tooth Erosion Potential of Zero and Carbonated Beverages in Korea: A Laboratory‐Based Study Focused on pH

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Objectives With increasing health consciousness, the consumption of zero‐calorie beverages (zero beverages) is also increasing. Zero beverages are devoid of sugar or alternative sugar content. Tooth erosion possibility continues to be reported in cases of carbonated beverage consumption.
Eun‐Ha Jung, Hyun‐Kyung Yim, Ji‐Hyun Min   +2 more
wiley   +1 more source

Fluorescence Reduction Neutralization Test: A Novel, Rapid, and Efficient Method for Characterizing the Neutralizing Activity of Antibodies Against Dengue Virus

Current Issues in Molecular Biology
Dengue virus (DENV) is a major public health threat in the tropical and subtropical regions of the world. Climate change resulting from global warming is further expanding DENV–endemic areas, adversely affecting public life and health.
Jiazheng Guo, Jiansheng Lu, Peng Du, Kexuan Cheng, Chao Lei, Yujia Jiang, Meiling Peng, Yating Li, Kaiyue Sun, Changyan Xu, Yunzhou Yu, Chen Gao, Qinglin Kang, Yixiao Zhang, Rong Wang, Zhixin Yang   +15 more
doaj   +1 more source

Comparison of measles IgG enzyme immunoassays (EIA) versus plaque reduction neutralization test (PRNT) for measuring measles serostatus: a systematic review of head-to-head analyses of measles IgG EIA and PRNT. [PDF]

BMC Infect Dis, 2023
Lutz CS, Hasan AZ, Bolotin S, Crowcroft NS, Cutts FT, Joh E, Loisate S, Moss WJ, Osman S, Hayford K.   +9 more
europepmc   +1 more source

Effectiveness of Toothbrush Containing Solar Cells and Titanium Dioxide Rod on Plaque Reduction During Caregiver‐Performed Toothbrushing—Randomised Crossover Clinical Trial

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Objectives This study was conducted to assess the effectiveness of a toothbrush containing solar cells and a titanium dioxide electrode (TiO2 toothbrush) compared with a normal toothbrush for removing plaque during caregiver‐performed oral hygiene care for elderly residents in nursing homes who require care. Methods A randomised, double‐blind,
Jumpei Murakami, Mai Niida
wiley   +1 more source