Results 21 to 30 of about 755,810 (388)

Plaque Rupture in Humans and Mice [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2007
Despite the many studies of murine atherosclerosis, we do not yet know the relevance of the natural history of this model to the final events precipitated by plaque disruption of human atherosclerotic lesions. The literature has become particularly confused because of the common use of terms such as “instability”, “vulnerable”, “rupture”, or even ...
Schwartz, Stephen M, Galis, Zorina S, Rosenfeld, Michael E, Falk, Erling   +3 more
openaire   +4 more sources

The Association Between Plasma Hyaluronan Level and Plaque Types in ST-Segment–Elevation Myocardial Infarction Patients

Frontiers in Cardiovascular Medicine, 2021
Background: The metabolism of hyaluronan (HA) is widely known to be involved in the process of acute coronary syndrome, but it is unknown how circulating HA levels change in ST-Segment–Elevation Myocardial Infarction (STEMI) patients and whether HA is ...
Jiannan Li, Yu Tan, Yu Tan, Zhaoxue Sheng, Peng Zhou, Chen Liu, Hanjun Zhao, Li Song, Jinying Zhou, Runzhen Chen, Yi Chen, Hongbing Yan, Hongbing Yan   +12 more
doaj   +1 more source

Plaque rupture complications in murine atherosclerotic vein grafts can be prevented by TIMP-1 overexpression. [PDF]

PLoS ONE, 2012
The current study describes the incidence and phenotype of plaque rupture complications in murine vein grafts. Since matrix metalloproteinases (MMPs) are highly involved in atherosclerotic plaque vulnerability and plaque rupture, we hypothesized that ...
Margreet R de Vries, Hans W M Niessen, Clemens W G M Löwik, Jaap F Hamming, J Wouter Jukema, Paul H A Quax   +5 more
doaj   +1 more source

The Time-Dependent Role of Bisphosphonates on Atherosclerotic Plaque Calcification

Journal of Cardiovascular Development and Disease, 2022
Atherosclerotic plaque calcification directly contributes to the leading cause of morbidity and mortality by affecting plaque vulnerability and rupture risk.
Amirala Bakhshian Nik, Hooi Hooi Ng, Manuel Garcia Russo, Francesco Iacoviello, Paul R. Shearing, Sergio Bertazzo, Joshua D. Hutcheson   +6 more
doaj   +1 more source

Morphometric and Mechanical Analyses of Calcifications and Fibrous Plaque Tissue in Carotid Arteries for Plaque Rupture Risk Assessment

IEEE Transactions on Biomedical Engineering, 2020
Objective: Atherosclerotic plaque rupture in carotid arteries is a major source of cerebrovascular events. Calcifications are highly prevalent in carotid plaques, but their role in plaque rupture remains poorly understood.
F. Gijsen, Bas Vis, H. Barrett, A. A. Zadpoor, H. Verhagen, D. Bos, A. V. D. van der Steen, A. Akyildiz   +7 more
semanticscholar   +1 more source

Noninvasive imaging of focal atherosclerotic lesions using fluorescence molecular tomography [PDF]

, 2014
Insights into the etiology of stroke and myocardial infarction suggest that rupture of unstable atherosclerotic plaque is the precipitating event. Clinicians lack tools to detect lesion instability early enough to intervene, and are often left to manage ...
Abendschein, Dana R., Achilefu, Samuel, Akers, Walter J., Culver, Joseph P., Maji, Dolonchampa, Nguyen, Annie, Pierce, Richard A., Shokeen, Monica, Solomon, Metasebya, Woodard, Pamela K.   +9 more
core   +2 more sources

Ruptured plaque or embolised thrombus [PDF]

Heart, 2004
A 38 year old woman with acute chest pain was admitted to the hospital. Positive troponins and electrocardiographic signs of anterior wall myocardial infarction during atrial fibrillation were found. Echocardiography (panel below) showed hypokinesia of the anterior wall and severe mitral stenosis (arrowhead; LV, left ventricle; SC, spontaneous contrast)
S Verheye, Paul Vermeersch, J Van der Heyden   +2 more
openaire   +2 more sources

Live Observation of Atherosclerotic Plaque Disruption in Apolipoprotein E-Deficient Mouse

Ultrasound International Open, 2015
Aim: The actual occurrence of spontaneous plaque rupture in mice has been a matter of debate. We report on an in vivo observation of the actual event of possible plaque disruption in a living ApoE-/- mouse.
V. Daeichin, J. C. Sluimer, K. van der Heiden, I. Skachkov, K. Kooiman, A. Janssen, B. Janssen, J. G. Bosch, N. de Jong, M. J. A. P. Daemen, A. F. W. van der Steen   +10 more
doaj   +1 more source

Prevalence, Features, and Prognosis of Artery‐to‐Artery Embolic ST‐Segment–Elevation Myocardial Infarction: An Optical Coherence Tomography Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background The major underlying mechanisms contributing to acute coronary syndrome are plaque rupture, plaque erosion, and calcified nodule. Artery‐to‐artery embolic myocardial infarction (AAEMI) was defined as ST‐segment–elevation myocardial infarction ...
Masahiro Takahata, Yasushi Ino, Takashi Kubo, Takashi Tanimoto, Akira Taruya, Kosei Terada, Hiroki Emori, Daisuke Higashioka, Yosuke Katayama, Amir Kh. M. Khalifa, Teruaki Wada, Yuichi Ozaki, Kunihiro Shimamura, Yasutsugu Shiono, Manabu Kashiwagi, Akio Kuroi, Suwako Fujita, Atsushi Tanaka, Takeshi Hozumi, Takashi Akasaka   +19 more
doaj   +1 more source

MRI-based biomechanical parameters for carotid artery plaque vulnerability assessment. [PDF]

, 2016
Carotid atherosclerotic plaques are a major cause of ischaemic stroke. The biomechanical environment to which the arterial wall and plaque is subjected to plays an important role in the initiation, progression and rupture of carotid plaques.
Gillard, Jonathan H, Nederveen, Aart J, Speelman, Lambert, Teng, Zhongzhao, van der Lugt, Aad   +4 more
core   +2 more sources