Results 21 to 30 of about 41,607 (304)

Atherosclerotic Plaque Rupture [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2003
It is generally established that the unstable plaque is the major cause of acute clinical sequelae of atherosclerosis. Unfortunately, terms indicating lesions prone to plaque instability, such as “vulnerable plaque,” and the different phenotypes of unstable plaques, such as plaque rupture, plaque fissuring, intraplaque hemorrhage, and erosion, are ...
Esther, Lutgens, Robert-Jan, van Suylen, Birgit C, Faber, Marion J, Gijbels, Petra M, Eurlings, Ann-Pascale, Bijnens, Kitty B, Cleutjens, Sylvia, Heeneman, Mat J A P, Daemen   +8 more
openaire   +2 more sources

Live Observation of Atherosclerotic Plaque Disruption in Apolipoprotein E-Deficient Mouse

Ultrasound International Open, 2015
Aim: The actual occurrence of spontaneous plaque rupture in mice has been a matter of debate. We report on an in vivo observation of the actual event of possible plaque disruption in a living ApoE-/- mouse.
V. Daeichin, J. C. Sluimer, K. van der Heiden, I. Skachkov, K. Kooiman, A. Janssen, B. Janssen, J. G. Bosch, N. de Jong, M. J. A. P. Daemen, A. F. W. van der Steen   +10 more
doaj   +1 more source

Seasonal Variations in the Pathogenesis of Acute Coronary Syndromes

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Seasonal variations in acute coronary syndromes (ACS) have been reported, with incidence and mortality peaking in the winter. However, the underlying pathophysiology for these variations remain speculative.
Osamu Kurihara, Masamichi Takano, Erika Yamamoto, Taishi Yonetsu, Tsunekazu Kakuta, Tsunenari Soeda, Bryan P. Yan, Filippo Crea, Takumi Higuma, Shigeki Kimura, Yoshiyasu Minami, Tom Adriaenssens, Niklas F. Boeder, Holger M. Nef, Chong Jin Kim, Vikas Thondapu, Hyung Oh Kim, Michele Russo, Tomoyo Sugiyama, Francesco Fracassi, Hang Lee, Kyoichi Mizuno, Ik‐Kyung Jang   +22 more
doaj   +1 more source

Mechanisms of Plaque Formation and Rupture [PDF]

Circulation Research, 2014
Atherosclerosis causes clinical disease through luminal narrowing or by precipitating thrombi that obstruct blood flow to the heart (coronary heart disease), brain (ischemic stroke), or lower extremities (peripheral vascular disease). The most common of these manifestations is coronary heart disease, including stable angina pectoris and the acute ...
Bentzon, Jacob Fog, Otsuka, Fumiyuki, Virmani, Renu, Falk, Erling   +3 more
openaire   +3 more sources

Prevalence, Features, and Prognosis of Artery‐to‐Artery Embolic ST‐Segment–Elevation Myocardial Infarction: An Optical Coherence Tomography Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background The major underlying mechanisms contributing to acute coronary syndrome are plaque rupture, plaque erosion, and calcified nodule. Artery‐to‐artery embolic myocardial infarction (AAEMI) was defined as ST‐segment–elevation myocardial infarction ...
Masahiro Takahata, Yasushi Ino, Takashi Kubo, Takashi Tanimoto, Akira Taruya, Kosei Terada, Hiroki Emori, Daisuke Higashioka, Yosuke Katayama, Amir Kh. M. Khalifa, Teruaki Wada, Yuichi Ozaki, Kunihiro Shimamura, Yasutsugu Shiono, Manabu Kashiwagi, Akio Kuroi, Suwako Fujita, Atsushi Tanaka, Takeshi Hozumi, Takashi Akasaka   +19 more
doaj   +1 more source

Morphological and Stress Vulnerability Indices for Human Coronary Plaques and Their Correlations with Cap Thickness and Lipid Percent: An IVUS-Based Fluid-Structure Interaction Multi-patient Study. [PDF]

PLoS Computational Biology, 2015
Plaque vulnerability, defined as the likelihood that a plaque would rupture, is difficult to quantify due to lack of in vivo plaque rupture data. Morphological and stress-based plaque vulnerability indices were introduced as alternatives to obtain ...
Liang Wang, Jie Zheng, Akiko Maehara, Chun Yang, Kristen L Billiar, Zheyang Wu, Richard Bach, David Muccigrosso, Gary S Mintz, Dalin Tang   +9 more
doaj   +1 more source

Importance of inflammation in arteriosclerotic plaque destabilization and rupture [PDF]

Vojnosanitetski Pregled, 2005
Introduction. Although Rudolf Virchow considered arteriosclerosis an inflammatory disease in his book Cellular Pathology published in 1858, the opinion that it was a degenerative arterial disease as a civilization disease prevailed.
Tatić Vujadin, Kanjuh Vladimir, Rafajlovski Saša I., Kostić Kristina, Šuščević Dušan   +4 more
doaj   +1 more source

A novel workflow combining plaque imaging, plaque and plasma proteomics identifies biomarkers of human coronary atherosclerotic plaque disruption

Clinical Proteomics, 2017
Background Atherosclerotic plaque rupture is the culprit event which underpins most acute vascular syndromes such as acute myocardial infarction. Novel biomarkers of plaque rupture could improve biological understanding and clinical management of ...
Regent Lee, Roman Fischer, Philip D. Charles, David Adlam, Alessandro Valli, Katalin Di Gleria, Rajesh K. Kharbanda, Robin P. Choudhury, Charalambos Antoniades, Benedikt M. Kessler, Keith M. Channon   +10 more
doaj   +1 more source

Developing a novel rabbit model of atherosclerotic plaque rupture and thrombosis by cold-induced endothelial injury

Journal of Biomedical Science, 2009
Background It is widely believed that atherosclerotic plaque rupture and subsequent thrombosis leads to acute coronary events and stroke. However, study of the mechanism and treatment of human plaque rupture is hampered by lack of a suitable animal model.
Jiang Zhi-Xin, Zhang Qing-Hua, Fang Shun-Miao   +2 more
doaj   +1 more source

Mean platelet volume and coronary plaque vulnerability: an optical coherence tomography study in patients with non-ST-elevation acute coronary syndrome

BMC Cardiovascular Disorders, 2019
Background The association between mean platelet volume (MPV) and coronary plaque vulnerability in patients with non-ST-elevation ACS (NSTE-ACS) has not been investigated.
Jun Wang, Xing Li, Jun Pu, Siyu Jin, Lu Jia, Xiaomei Li, Fen Liu, Yining Yang   +7 more
doaj   +1 more source