Results 21 to 30 of about 700,142 (373)
Background: The metabolism of hyaluronan (HA) is widely known to be involved in the process of acute coronary syndrome, but it is unknown how circulating HA levels change in ST-Segment–Elevation Myocardial Infarction (STEMI) patients and whether HA is ...
Jiannan Li+12 more
doaj +1 more source
Plaque Rupture in Humans and Mice [PDF]
Despite the many studies of murine atherosclerosis, we do not yet know the relevance of the natural history of this model to the final events precipitated by plaque disruption of human atherosclerotic lesions. The literature has become particularly confused because of the common use of terms such as “instability”, “vulnerable”, “rupture”, or even ...
Schwartz, Stephen M+3 more
openaire +4 more sources
The Time-Dependent Role of Bisphosphonates on Atherosclerotic Plaque Calcification
Atherosclerotic plaque calcification directly contributes to the leading cause of morbidity and mortality by affecting plaque vulnerability and rupture risk.
Amirala Bakhshian Nik+6 more
doaj +1 more source
Objective: Atherosclerotic plaque rupture in carotid arteries is a major source of cerebrovascular events. Calcifications are highly prevalent in carotid plaques, but their role in plaque rupture remains poorly understood.
F. Gijsen+7 more
semanticscholar +1 more source
Plaque rupture complications in murine atherosclerotic vein grafts can be prevented by TIMP-1 overexpression. [PDF]
The current study describes the incidence and phenotype of plaque rupture complications in murine vein grafts. Since matrix metalloproteinases (MMPs) are highly involved in atherosclerotic plaque vulnerability and plaque rupture, we hypothesized that ...
Margreet R de Vries+5 more
doaj +1 more source
Seasonal Variations in the Pathogenesis of Acute Coronary Syndromes
Background Seasonal variations in acute coronary syndromes (ACS) have been reported, with incidence and mortality peaking in the winter. However, the underlying pathophysiology for these variations remain speculative.
Osamu Kurihara+22 more
doaj +1 more source
Ruptured plaque or embolised thrombus [PDF]
A 38 year old woman with acute chest pain was admitted to the hospital. Positive troponins and electrocardiographic signs of anterior wall myocardial infarction during atrial fibrillation were found. Echocardiography (panel below) showed hypokinesia of the anterior wall and severe mitral stenosis (arrowhead; LV, left ventricle; SC, spontaneous contrast)
S Verheye+2 more
openaire +2 more sources
Live Observation of Atherosclerotic Plaque Disruption in Apolipoprotein E-Deficient Mouse
Aim: The actual occurrence of spontaneous plaque rupture in mice has been a matter of debate. We report on an in vivo observation of the actual event of possible plaque disruption in a living ApoE-/- mouse.
V. Daeichin+10 more
doaj +1 more source
Predictors and morphological properties of culprit healed plaques in patients with angina pectoris
Abstract Background Plaque healing may serve a vital function in the natural progression of atherosclerotic disease. This study sought to investigate predictors and morphological characteristics of healed plaque (HP) among angina pectoris (AP) patients.
Hongying Yao+5 more
wiley +1 more source
Background The major underlying mechanisms contributing to acute coronary syndrome are plaque rupture, plaque erosion, and calcified nodule. Artery‐to‐artery embolic myocardial infarction (AAEMI) was defined as ST‐segment–elevation myocardial infarction ...
Masahiro Takahata+19 more
doaj +1 more source