Results 121 to 130 of about 160,587 (337)

Smart Catheters for Diagnosis, Monitoring, and Therapy

Advanced Healthcare Materials, EarlyView.
This study presents a comprehensive review of smart catheters, an emerging class of medical devices that integrate embedded sensors, robotics, and communication systems, offering increased functionality and complexity to enable real‐time health monitoring, diagnostics, and treatment. Abstract This review explores smart catheters as an emerging class of
Azra Yaprak Tarman, Samiha Ahmed, Majed Othman Althumayri, Megan Guy, Darlenne Chavez Lugo, Frances S. Ligler, George T. Ligler, Rahmi Oklu, Hiroshi Kawahira, Michael J. McShane, Jun Kameoka, Jonathan Bova, Hatice Ceylan Koydemir   +12 more
wiley   +1 more source

Evaluating the Antiviral Efficacy of Encapsulated PKC Inhibitor BIM‐I against influenza A Virus Infection

Advanced Healthcare Materials, EarlyView.
This study explores nanoparticle delivery of the protein kinase C inhibitor bisindolylmaleimide‐I (BIM‐I) to combat influenza A virus infections. Encapsulation in biodegradable PLGA nanoparticles improved safety while maintaining the compound's strong antiviral activity.
Laura Klement, Jana Ismail, Josefine Schroeder, Amod Godbole, Johanna Schreiber, Christine Weber, Zoltan Cseresnyes, Marc T. Figge, Bettina Löffler, Ulrich S. Schubert, Stephanie Schubert, Christina Ehrhardt, Carsten Hoffmann   +12 more
wiley   +1 more source

Recent advances in Ni-H2 technology at NASA Lewis Research Center [PDF]

, 1986
The NASA Lewis Research Center has concentrated its efforts on advancing the Ni-H2 system technology for low Earth orbit applications. Component technology as well as the design principles were studied in an effort to understand the system behavior and ...
Britton, D. L., Gonzalezsanabria, O. D., Reid, M. A., Smithrick, J. J.   +3 more
core   +1 more source

PhotoPoint Photodynamic Therapy Promotes Stabilization of Atherosclerotic Plaques and Inhibits Plaque Progression

Journal of the American College of Cardiology, 2008
The purpose of this study was to determine how photodynamic therapy (PDT) promotes stabilization and reduction of regional atherosclerosis.Photodynamic therapy, a combination of photosensitizer and targeted light to promote cell apoptosis, has been shown to reduce atherosclerotic plaque inflammation.Forty New Zealand White rabbits were fed with ...
Waksman, Ron, McEwan, Pauline E., Moore, Travis I., Pakala, Rajbabu, Kolodgie, Frank D., Hellinga, David G., Seabron, Rufus C., Rychnovsky, Steven J., Vasek, Jeffrey, Scott, Robert W., Virmani, Renu   +10 more
openaire   +2 more sources

Interfacial Bioengineering of Dynamic Networks Hybrid Hydrogel for Programmed Intervention in Oral Precancerous Epithelial States

Advanced Healthcare Materials, EarlyView.
This study develops a dual‐bioinspired hydrogel, MSA@PGel (macrophage membrane‐coated and salvianolic acid B/5‐aminolevulinic acid co‐loaded liposomes embedded in a polydopamine‐based gel), that integrates macrophage membrane‐mediated active targeting and mussel‐inspired wet adhesion for programmed intervention in oral precancerous lesions.
Xiaoxian Zhao, Ao Zheng, Zhengyan Zhao, Qilin Li, Tianhao Wan, Tanjun Deng, Ying Zhang, Lingyan Cao, Lan Wu   +8 more
wiley   +1 more source

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

Inhibiting Integrin α5 Cytoplasmic Domain Signaling Reduces Atherosclerosis and Promotes Arteriogenesis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundFibronectin in endothelial basement membranes promotes endothelial inflammatory activation and atherosclerosis but also promotes plaque stability and vascular remodeling. The fibronectin receptor α5 subunit is proinflammatory through binding to
Madhusudhan Budatha, Jiasheng Zhang, Zhen W. Zhuang, Sanguk Yun, James E. Dahlman, Daniel G. Anderson, Martin A. Schwartz   +6 more
doaj   +1 more source

Macrophage Iron, Hepcidin, and Atherosclerotic Plaque Stability

Experimental Biology and Medicine, 2007
Hepcidin has emerged as the key hormone in the regulation of iron balance and recycling. Elevated levels increase iron in macrophages and inhibit gastrointestinal iron uptake. The physiology of hepcidin suggests an additional mechanism by which iron depletion could protect against atherosclerotic lesion progression.
openaire   +3 more sources

Sculpting the Future of Bone: The Evolution of Absorbable Materials in Orthopedics

Advanced Materials, EarlyView.
This review summarizes the current status of polymeric, ceramic, and metallic absorbable materials in orthopedic applications, and highlights several innovative strategies designed to enhance mechanical performance, control degradation, and promote bioactivity. We also discuss the progress and translational potential of absorbable materials in treating
Zhao Wang, Zehui Lv, Xuejie Cai, Yingjie Wang, Bo Peng, Haojing Xu, Hualuo Pang, Xingdong Yang, Jiawei Xu, Yixin Bian, Bin Feng, Peng Wen, Yufeng Zheng, Xisheng Weng   +13 more
wiley   +1 more source

Long non-coding RNA AK023617 orchestrates atherosclerosis by regulating the circadian rhythm of immunity-related GTPase family M protein in macrophages

Non-coding RNA Research
Acute coronary events show a diurnal rhythm, and atherosclerotic plaque vulnerability, as a histomorphological characteristic of major adverse cardiovascular events, is a key target for intervention. Although oscillating microRNAs reduce plaque stability
Rongzhe Lu, Hengxuan Cai, Yige Liu, Guanpeng Ma, Jiaxin Wang, Miao Yan, Zhenming Zhang, Bo Yu, Zhaoying Li, Shaohong Fang   +9 more
doaj   +1 more source