Results 231 to 240 of about 162,485 (319)

Serotonergic modulators in Alzheimer's disease: a hope in the hopeless condition

open access: yesChemistry &Biodiversity, Accepted Article.
Alzheimer disease (AD) is the main cause of dementia worldwide. AD is a progressive brain neurodegenerative disease due to genetic and environmental factors that induce a progressive accumulation of intracellular hyperphosphorylated tau protein and extracellular amyloid protein (Aβ).
Ali I. Al-Gareeb   +5 more
wiley   +1 more source

Ethnomedicinal uses, phytochemistry, pharmacological activities, and toxicology of the subfamily Gomphrenoideae (Amaranthaceae): A comprehensive review

open access: yesChemistry &Biodiversity, Accepted Article.
The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its promising ...
Dayanna Isabel Araque Gelves   +3 more
wiley   +1 more source

Vascular smooth muscle cell-derived hydrogen sulfide promotes atherosclerotic plaque stability via TFEB (transcription factor EB)-mediated autophagy. [PDF]

open access: yesAutophagy, 2022
Chen Z   +12 more
europepmc   +1 more source

Myeloperoxidase-oxidized high density lipoprotein impairs atherosclerotic plaque stability by inhibiting smooth muscle cell migration

open access: gold, 2017
Boda Zhou   +11 more
openalex   +1 more source

A Proteomics Profiling Reveals the Neuroprotective Effects of Melatonin on Exogenous β‐amyloid‐42 Induced Mitochondrial Impairment, Intracellular β‐amyloid Accumulation and Tau Hyperphosphorylation in Human SH‐SY5Y Cells

open access: yesCell Biology International, EarlyView.
ABSTRACT Alzheimer's disease (AD) is prevalent in the elderly population and characterized by the intracellular accumulation of neurofibrillary tangles (NFTs), composed of tau proteins, and extracellular deposition of beta‐amyloid protein (Aβ). The present study aimed to investigate the neuroprotective effects of melatonin on Aβ42‐induced AD‐like ...
Jiraporn Panmanee   +11 more
wiley   +1 more source

Research on the correlation between activating transcription factor 3 expression in the human coronary artery and atherosclerotic plaque stability. [PDF]

open access: yesBMC Cardiovasc Disord, 2021
Peng J   +9 more
europepmc   +1 more source

Fractional Flow Reserve Directed Percutaneous Coronary Intervention Optimization Using High‐Definition Intravascular Ultrasound in Non‐ST‐Segment Elevation Acute Coronary Syndrome Versus Chronic Coronary Syndrome

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Intravascular ultrasound (IVUS)‐guided optimization of suboptimal fractional flow reserve (FFR) following percutaneous coronary intervention (PCI) results in a significant increase in both post‐PCI FFR and minimal lumen and stent areas (MLA and MSA, respectively).
Frederik T. W. Groenland   +9 more
wiley   +1 more source

Sex Differences in Clinical Characteristics, Psychosocial Factors, and Outcomes Among Patients With Stable Coronary Heart Disease: Insights from the STABILITY (Stabilization of Atherosclerotic Plaque by Initiation of Darapladib Therapy) Trial

open access: gold, 2017
Patrícia O. Guimarães   +14 more
openalex   +1 more source

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