Results 241 to 250 of about 160,587 (337)

Therapeutic ultrasound combined with microbubbles improves atherosclerotic plaque stability by selectively destroying the intraplaque neovasculature

, 2020
Xinzhong Li, Shengcun Guo, Tongwen Xu, Xiang He, Yili Sun, Xiaoqiang Chen, Shiping Cao, Xiaoyun Si, Wangjun Liao, Yulin Liao, Yuan Han, Jianping Bin   +11 more
openalex   +1 more source

DNase1 RS1053874 Polymorphism is Associated with Early Neurological Recovery through NET Modulation and with Long‐Term Survival in Ischemic Stroke: A Prospective Cohort Study

Annals of Neurology, EarlyView.
Objective Immunothrombosis contributes to ischemic stroke pathophysiology through neutrophil extracellular trap (NET) formation, which promotes thrombus stabilization and microvascular dysfunction. DNase1 is the principal endonuclease responsible for NET degradation.
B. Díaz‐Benito, P. Calleja, L. Alzamora, A. Ruiz‐García, A. Martínez‐Salio, M. Muñoz‐García, F. Ostos, A. García‐Culebras, A. Moraga, M.A. Moro, I. Lizasoain   +10 more
wiley   +1 more source

Single-cell transcriptome integrated with genome-wide association study reveals heterogeneity of carotid and femoral plaques and its association with plaque stability. [PDF]

Sci Rep
Hou X, Li Z, Lin J, Lin W, Li L, Zheng X, Lai X, Zhu L, Guo P, Cai F, Zhang J, Li W, Yang C, Dai Y.   +13 more
europepmc   +1 more source

Probucol Attenuates Inflammation and Increases Stability of Vulnerable Atherosclerotic Plaques in Rabbits

, 2011
Tingting Li, Wenqiang Chen, Fengshuang An, Hongbo Tian, Jianning Zhang, Jie Peng, Yun Zhang, Yuan Guo   +7 more
openalex   +2 more sources

Ablation of Interferon Regulatory Factor 3 Promotes the Stability of Atherosclerotic Plaques [PDF]

, 2017
Imoh S. Okon, Ding Ye, Ming‐Hui Zou
openalex   +1 more source

When Does Alzheimer's Disease Start? Plasma Aβ42/40 Assays Show Steep Changes at Aβ‐PET Centiloid 15, Mean Age of 66 Years

Annals of Neurology, EarlyView.
Objective Sporadic late‐onset Alzheimer's disease (AD) is characterized by a long pre‐clinical phase where amyloid‐beta (Aβ) and tau begin to accumulate in the brain. The primary objective was to determine the age at which AD starts by finding the average population age when both positron emission tomography (PET) Aβ (Aβ‐PET) and plasma Aβ42/40 become ...
Rodrigo Cánovas, Timothy Cox, Vincent Doré, Pierrick Bourgeat, Jurgen Fripp, Azadeh Feizpour, Rosita Shishegar, Christopher J. Fowler, Simon M. Laws, Tenielle Porter, Stephanie Rainey‐Smith, Leslie M. Shaw, Randall J. Bateman, Yan Li, Ovod Vitaliy, Michael W. Weiner, John C. Morris, Tammie L.S. Benzinger, Suzanne E. Schindler, Akinori Nakamura, Takeshi Iwatsubo, Takeshi Ikeuchi, Takashi Kato, Paul Maruff, Hamid R. Sohrabi, Christopher C. Rowe, Ralph N. Martins, Colin L. Masters, James D. Doecke, for the Alzheimer's Disease Neuroimaging Initiative   +29 more
wiley   +1 more source

Integrating genomic profiling to clinical data: assessing the impact of CD147 expression on plaque stability. [PDF]

Front Cardiovasc Med
Chen Y, Lu S, Ren Y, Fan J, Bao CP, Zhang X, Shi YK, Wang Y, Yang LX.   +8 more
europepmc   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source

Trem2 Agonist Reprograms Foamy Macrophages to Promote Atherosclerotic Plaque Stability-Brief Report. [PDF]

Arterioscler Thromb Vasc Biol
Patterson MT, Xu Y, Hillman H, Osinski V, Schrank PR, Kennedy AE, Barrow F, Zhu A, Tollison S, Shekhar S, Stromnes IM, Tassi I, Wu D, Revelo XS, Binstadt BA, Williams JW.   +15 more
europepmc   +1 more source

Genetic deletion or TWEAK blocking antibody administration reduce atherosclerosis and enhance plaque stability in mice [PDF]

, 2014
Cristina Sastre, Valvanera Fernández‐Laso, Julio Madrigal‐Matute, Begoña Muñoz‐García, Juan Antonio Moreno, Carlos Pastor‐Vargas, Patricia Llamas‐Granda, Linda C. Burkly, Jesús Egido, José Luis Martín‐Ventura, Luis Miguel Blanco‐Colio   +10 more
openalex   +1 more source