Results 251 to 260 of about 162,485 (319)

Antibacterial and antiviral activity of a highly efficient electrospun r‐PET nanofiber

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract Since the COVID‐19 pandemic, the emergence of clean air has increased interest in developing antimicrobial air filters, targeting sterilization and public health concerns. Nanofibers are a promising approach due to their high efficiency in air filtration, while nanoparticles adhered to the fibre surfaces can improve safety due to the biocidal ...
Karine Machry, Danilo M. Melo, Daniela Patrícia Freire Bonfim, Paulo Augusto Marques Chagas, Felipe de Aquino Lima, Clovis Wesley Oliveira de Souza, Luiz Tadeu Moraes Figueredo, Mônica Lopes Aguiar, André Bernardo   +8 more
wiley   +1 more source

New Pyridobenothiazolone Derivatives Display Nanomolar Pan‐Serotype Anti‐Dengue Virus Activity

ChemMedChem, EarlyView.
A ligand‐based strategy is employed, starting from hit compound 2, to develop the C‐2 modified pyridobenzothiazolone 19 as a pan‐serotype nanomolar DENV‐1‐4 inhibitor. Investigations of the mechanism reveal the peculiar ability to abolish the infectivity of virions in a second infection.
Tommaso Felicetti, Chin Piaw Gwee, Kitti Wing Ki Chan, Giacomo Pepe, Ciro Milite, Pietro Campiglia, Satoru Watanabe, Muhammad Danial Bin Mohd Mazlan, Stefano Sabatini, Serena Massari, Oriana Tabarrini, Gianluca Sbardella, Subhash G. Vasudevan, Giuseppe Manfroni   +13 more
wiley   +1 more source

Deletion or Inhibition of NOD1 Favors Plaque Stability and Attenuates Atherothrombosis in Advanced Atherogenesis ^†. [PDF]

Cells, 2020
González-Ramos S, Fernández-García V, Recalde M, Rodríguez C, Martínez-González J, Andrés V, Martín-Sanz P, Boscá L.   +7 more
europepmc   +1 more source

Down-regulation of microRNA-342-5p or Up-regulation of Wnt3a Inhibits Angiogenesis and Maintains Atherosclerotic Plaque Stability in Atherosclerosis Mice.

Nanoscale Res Lett, 2021
Sun H, Feng J, Ma Y, Cai D, Luo Y, Wang Q, Li F, Zhang M, Hu Q.   +8 more
europepmc   +1 more source

Bifunctional supramolecular nanofiber inhibits atherosclerosis by enhancing plaque stability and anti-inflammation in apoE^-/- mice. [PDF]

Theranostics, 2020
Shang Y, Ma C, Zhang J, Wang Z, Ren C, Luo X, Peng R, Liu J, Mao J, Shi Y, Fan G.   +10 more
europepmc   +1 more source

Microaxial pump‐supported coronary surgery without CPB to optimize outcome in severely impaired left ventricles

ESC Heart Failure, EarlyView.
Abstract Aims Cardiopulmonary bypass (CPB) is the standard approach for coronary artery bypass grafting (CABG) in advanced ischaemic cardiomyopathy. Microaxial pump support has been envisioned to allow for beating‐heart CABG without CPB (MPCAB), thereby avoiding CPB‐inherent complications.
Anna Kathrin Assmann, Merve Arik‐Doganay, Sebastian Waßenberg, Payam Akhyari, Artur Lichtenberg, Alexander Assmann   +5 more
wiley   +1 more source

Dilated cardiomyopathy evaluation with Imagenomics: combining multimodal cardiovascular imaging and genetics

ESC Heart Failure, EarlyView.
Systematic approach to dilated cardiomyopathy diagnosis. Dilated cardiomyopathy is a clinical diagnosis characterized by the presence of left ventricular dilatation and systolic disfunction unexplained by abnormal loading conditions or coronary artery disease.
Kristian Galanti, Ghaith Sharaf Dabbagh, Fabrizio Ricci, Sabina Gallina, Roberta Giansante, Ron Jacob, Edmond Obeng‐Gyimah, Leslie T. Cooper Jr, Sanjay K. Prasad, David H. Birnie, Andrew P. Landstrom, Selma F. Mohammed, Saidi Mohiddin, Mohammed Y. Khanji, Anwar A. Chahal   +14 more
wiley   +1 more source

Benchmark Response (BMR) Values for In Vivo Mutagenicity Endpoints

Environmental and Molecular Mutagenesis, EarlyView.
ABSTRACT The benchmark dose (BMD) approach constitutes the most effective and pragmatic strategy for the derivation of a point of departure (PoD) for comparative potency analysis, risk assessment, and regulatory decision‐making. There is considerable controversy regarding the most appropriate benchmark response (BMR) for genotoxicity endpoints.
Paul A. White, Guangchao Chen, Nikolai Chepelev, Madison A. Bell, Lauren R. Gallant, George E. Johnson, Andreas Zeller, Marc A. Beal, Alexandra S. Long   +8 more
wiley   +1 more source

Enhanced Blood‐Brain Barrier Penetrability of BACE1 SiRNA‐Loaded Prussian Blue Nanocomplexes for Alzheimer's Disease Synergy Therapy

Exploration, EarlyView.
BACE1 interfering RNA, metallothionein and ruthenium complexes ([Ru(bpy)2dppz]2+) were all loaded in prussian blue nanoparticles (PRM‐siRNA). PRM‐siRNA under near‐infrared light irradiation showed good photothermal effect and triggered instantaneous opening of blood‐brain barrier for enhanced drug delivery.
Xiaoyuan Ding, Yanyu Hu, Xiaotong Feng, Zekun Wang, Qile Song, Chunxue Dai, Bangjia Yang, Xiaoyan Fu, Dongdong Sun, Cundong Fan   +9 more
wiley   +1 more source

Biomaterials‐Involved Construction of Extracellular Matrices for Tumor Blockade Therapy

Exploration, EarlyView.
Extracellular matrices (ECMs) play a crucial role in tumor growth and metastases by providing structural support and facilitating tumor cell proliferation. In this review, we explore the development of artificial ECMs engineered through biomineralization, fibrogenesis, and gelation. These bioinspired ECMs create a protective barrier around tumor cells,
Jinfeng Sun, Yang Liu, Jingshan Sun, Jianxun Ding, Xuesi Chen   +4 more
wiley   +1 more source