Results 61 to 70 of about 591,503 (279)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Evaluation of the Storage Stability and Quality Properties of Fresh Noodles Mixed with Plasma-Activated Water

Foods, 2022
Enhancing the quality retention of fresh noodles remains challenging. In this study, we investigated the effect of dough mixing with plasma-activated water (PAW) of different activation times on the storage stability and quality characteristics of fresh ...
Yawei Wang, Yuchang Liu, Man Li, Meng Ma, Qingjie Sun   +4 more
doaj   +1 more source

Microporous structure with layered interstitial surface treatment, and method and apparatus for preparation thereof [PDF]

, 1992
A microporous structure with layered interstitial surface treatments, and the method and apparatus for its preparation are disclosed. The structure is prepared by sequentially subjecting a uniformly surface treated structure to atomic oxygen treatment to
Koontz, Steven L.
core   +1 more source

Spark plasma sintered carbon electrodes for electrical double layer capacitor applications [PDF]

, 2011
The spark plasma sintering (SPS) is an emerging process for shaping any type of materials (metals, ceramic, polymers and their composites). The advantage of such a process is to prepare densified ceramic materials in a very short time, while keeping the ...
Chevallier, Geoffroy, Daffos, Barbara, Estournès, Claude, Simon, Patrice   +3 more
core   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Hybrid plasma discharges for energy-efficient production of plasma-activated water

Chemical Engineering Journal, 2023
Plasma-activated water (PAW), an emerging and cost-effective disinfectant produced from the interaction between non-thermal plasma and water, was generated with a newly designed hybrid plasma discharge (HPD) reactor. The HPD reactor produces two simultaneous plasma discharges within one power source, one from the high-voltage electrode above the liquid
Hadinoto, K, Rao, NRH, Astorga, JB, Zhou, R, Biazik, J, Zhang, T, Masood, H, Cullen, PJ, Prescott, S, Henderson, RK, Trujillo, FJ, Hanumanth Rao, Naras   +11 more
openaire   +2 more sources

Ingestive behaviour and physiology of the medicinal leech [PDF]

, 1988
Ingestion lasts 25 min in Hirudo medicinalis and is characterized by pharyngeal peristalsis which fills the crop. This peristalsis has an initial rate of 2.4 Hz which decays smoothly to 1.2 Hz at termination of ingestion. During ingestion, the leech body
Dickinson, M. H., Fliegner, K. H., Freedman, E., Lent, C. M.   +3 more
core  

Medial prefrontal cortex neuronal activation and synaptic alterations after stress-induced reinstatement of palatable food seeking: a study using c-fos-GFP transgenic female rats [PDF]

, 2012
Relapse to maladaptive eating habits during dieting is often provoked by stress and there is evidence for a role of ovarian hormones in stress responses and feeding.
Baumann, Michael H, Calu, Donna J, Cifani, Carlo, Hope, Bruce T, Khuc, Thi, Koya, Eisuke, Liu, Qing-Rong, Lupica, Carl R, Marchant, Nathan J, Navarre, Brittany M, Pickel, James, Shaham, Yavin   +11 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Physical properties of natural and processed water using dielectric barrier and gliding arc discharge [PDF]

AIP Advances
In this study, we produced an atmospheric pressure dielectric barrier and a gliding arc plasma jet and explored their impact on various physical properties of different natural and processed waters. The investigation was carried out under varying volumes,
Roshan Chalise, Om Shree Rijal, Dipak Oli, Krishna Regmi, Sadip Nepal, Raju Khanal   +5 more
doaj   +1 more source