Biomarkers and overall survival in patients with advanced hepatocellular carcinoma treated with TGF-βRI inhibitor galunisertib. [PDF]
, 2020 BackgroundTransforming growth factor beta (TGF-β) signalling is involved in the development of hepatocellular carcinoma (HCC). We followed changes in biomarkers during treatment of patients with HCC with the TGF-βRI/ALK5 inhibitor galunisertib ...
Benhadji, Karim A +13 more
core +2 more sources
Plasma Biomarkers and Incident CKD Among Individuals Without Diabetes
Kidney Medicine, 2023 Rationale & Objective: Biomarkers of kidney disease progression have been identified in individuals with diabetes and underlying chronic kidney disease (CKD).
Dustin Le +16 more
doaj +1 more source
A Panel of Plasma Biomarkers for Differential Diagnosis of Parkinsonian Syndromes
Frontiers in Neuroscience, 2022 Objective The aim of our study is to explore the most reliable panel of plasma biomarkers for differential diagnosis of parkinsonian syndromes (PDSs).
Qi Li +9 more
semanticscholar +1 more source
A proteomic atlas of senescence-associated secretomes for aging biomarker development. [PDF]
, 2020 The senescence-associated secretory phenotype (SASP) has recently emerged as a driver of and promising therapeutic target for multiple age-related conditions, ranging from neurodegeneration to cancer.
Basisty, Nathan +11 more
core +1 more source
Advances in blood biomarkers for Alzheimer disease (AD): A review
Kaohsiung Journal of Medical SciencesAlzheimer disease (AD) and Alzheimer Disease and Related Dementias (AD/ADRD) are growing public health challenges globally affecting millions of older adults, necessitating concerted efforts to advance our understanding and management of these conditions.
Araya Dimtsu Assfaw +2 more
doaj +1 more source
Plasma biomarkers for prognosis of cognitive decline in patients with mild cognitive impairment
Brain Communications, 2022 Plasma-based biomarkers present a promising approach in the research and clinical practice of Alzheimer's disease as they are inexpensive, accessible and minimally invasive.
P. Kivisäkk +11 more
semanticscholar +1 more source
Changes in vitamin biomarkers during a 2-year intervention trial involving increased fruit and vegetable consumption by free-living volunteers [PDF]
, 2009 Peer reviewedPublisher ...
Antonia C. Hardcastle +11 more
core +2 more sources
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Quantitative variability of 342 plasma proteins in a human twin population
Molecular Systems Biology, 2015 The degree and the origins of quantitative variability of most human plasma proteins are largely unknown. Because the twin study design provides a natural opportunity to estimate the relative contribution of heritability and environment to different ...
Yansheng Liu +11 more
doaj +1 more source
Associations of amyloid and neurodegeneration plasma biomarkers with comorbidities
Alzheimer's & Dementia, 2021 Blood‐based biomarkers of amyloid pathology and neurodegeneration are entering clinical use. It is critical to understand what factors affect the levels of these markers.
Jeremy A. Syrjanen +10 more
semanticscholar +1 more source