Results 111 to 120 of about 145,148 (243)

Cellular Membrane‐Targeted Europium(III) Probe for Selective and Time‐Resolved Detection of Peroxynitrite

Chemistry – A European Journal, EarlyView.
We report a cellular membrane‐targeted europium(III) probe, Eu.Chol, that enables selective, time‐resolved detection of peroxynitrite (ONOO−) at the cell membrane interface. Eu.Chol demonstrates efficient incorporation into liposomes and Jurkat cells, with minimal response to H2O2, establishing a modular platform for subcellular ONOO− sensing ...
Jamie Webb, Rebecca Tiffany, Karolis Norvaisa, Hennie Valkenier, Lea Miebach, Sander Bekeschus, Stephen J. Butler   +6 more
wiley   +1 more source

From Caffeine to Aspirin: Everyday Molecules as Triggers for Genetically Encoded Proximity Systems

Chemistry – A European Journal, EarlyView.
This Perspective article highlights how familiar dietary ingredients and over‐the‐counter (OTC) drugs (such as caffeine and its metabolites, SA, and aspirin) can be repurposed as clinically translatable chemical triggers for genetically encoded proximity systems.
Mingguang Cui, Tianlu Wang, Yaoyu Han, Yun Huang, Tien‐Hung Lan, Yunbin Zhou   +5 more
wiley   +1 more source

Circulating monocyte partitioning and its alteration in hematological chronic neoplasms

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Circulating monocyte partitioning refers to the relative quantification of the three main monocyte subsets in the peripheral blood, namely classical (cMo), intermediate (iMo), and non‐classical (ncMo) monocytes, as assessed by flow cytometry, a new nomenclature described 15 years ago.
Sihem Tarfi, Dorothée Selimoglu‐Buet, Ivan Sloma, Orianne Wagner‐Ballon, on behalf of the French group CytHem‐LMMC   +4 more
wiley   +1 more source

An Unusual Pattern of Hepatic Involvement in Plasma Cell Leukemia. [PDF]

Cureus
Paz MAM, Hamed A, Ehster C, Schat R, Gupta S, Elbaz Younes I, Park BU.   +6 more
europepmc   +1 more source

DinoFlow: Self‐supervised pretraining in flow cytometry enables accurate detection of common hematopathological disorders

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Flow cytometry is an essential component of routine hematological lab testing. Many computational methods have been proposed for the analysis of flow cytometry data, but most have focused on supervised learning for just one or a few specific disorders.
Brendan O'Fallon, Muir Morrison, Mattia Medina Grespan, Nicholas C. Spies, David P. Ng   +4 more
wiley   +1 more source

Plasma cell leukemia: genomic features and their potential relevance for exploring clinical actionability. [PDF]

Blood Adv
Mohan M, Danziger N, Akhtar OS, Narra R, Pasquini MC, Radhakrishnan S, Dhakal B, D'Souza A, Lin D, Ho C, Kurzrock R.   +10 more
europepmc   +1 more source

Therapy-Related Acute Myeloid Leukemia Following Plasma Cell Leukemia: A Case Report and Literature Review. [PDF]

Clin Case Rep
Chen S, Hu J, Zhang Q, Mao L, Jiang Q, Qian C, Zhang W, Jin K, Li J, Wang JN, Zhao Y.   +10 more
europepmc   +1 more source

Plasma cell leukemia: another piece of the puzzle. [PDF]

Haematologica, 2023
Musto P, Wäsch R.
europepmc   +1 more source

Hepatic Mechanisms and Therapeutic Target Underpinning Hypercoagulation in Obesity: Insights From Genetic and Transcriptomic Analyses

Exploration, EarlyView.
Obesity‐linked hypercoagulation is driven by fibrinogen overproduction in a specific hepatocyte cluster via IL6 signalling. Genetic and mechanistic studies reveal this pathway as a key target for therapies to mitigate clotting risks and associated complications in obese individuals.
Shumin Li, Gengchen Feng, Xin Huang, Xiao Teng, Ziyi Yang, Yue Liu, Yonghui Jiang, Tao Zhu, Teng Liu, Yunfei Xu, Chang Pan, Han Zhao, Shaozhuang Liu, Shigang Zhao, Zi‐Jiang Chen   +14 more
wiley   +1 more source

Combined chemotherapy with sequential allogeneic hematopoietic stem cell transplantation successfully treats primary plasma cell leukemia: a case report. [PDF]

Front Oncol
Dong X, Wang J, Tian Y, Wang L, Wang W.
europepmc   +1 more source