Results 131 to 140 of about 145,148 (243)

Integrated one‐pot CRISPR‐Cas detection: Addressing strategies and future prospects

open access: yesInterdisciplinary Medicine, EarlyView.
Integrated one‐pot CRISPR‐Cas detection significantly simplifies workflows, reduces cross‐contamination risks, and shortens turnaround times, making it highly suitable for point‐of‐care testing (POCT) and resource‐limited settings. Key challenges include system compatibility issues between Cas proteins and isothermal amplification, limited multiplexing
Jian Zhou   +6 more
wiley   +1 more source

A Comprehensive Study of Bidirectional Interactions Between the Human Microbiome and Blood Malignancies and Hematologic Conditions: Focus on Novel Therapeutic Strategies

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Microbiota‐targeted therapeutic strategies in hematological disorders. aHSCT: Transplanted immune cells from the donor may attack the recipient's tissues, especially when damage to the intestinal epithelium disrupts the gut microbiota, contributing to GVHD. Maintaining a balanced gut microbiota that supports immune regulation helps reduce GVHD risk and
Alireza Molajafari   +3 more
wiley   +1 more source

Efficacy of BCMA CAR-T cell therapy and subsequent strategies in refractory and relapsed plasma cell leukemia: a retrospective cohort study. [PDF]

open access: yesFront Immunol
Guo Y   +13 more
europepmc   +1 more source

A Practical and Efficient Multiplex qPCR Assay for Simultaneous Detection of HLA Cross‐Reactive Groups and Human Platelet Antigens

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
This assay enables multiplex genotyping of HLA‐CREGs and HPA alleles from whole blood using qPCR with an integrated parallel negative control. Results are interpreted based on amplification curves and Ct values, with validity dependent on strict quality control criteria for both the target reactions and the negative control.
Huimin Ji   +9 more
wiley   +1 more source

Plasma cell leukemia in a 34-year-old male: rare scenario case report. [PDF]

open access: yesAnn Med Surg (Lond), 2023
Issa M   +4 more
europepmc   +1 more source

COMIP‐002: 27‐color flow cytometry for measurable residual disease detection in B‐cell lymphoblastic leukemia

open access: yes
Cytometry Part B: Clinical Cytometry, EarlyView.
Ryan C. Shean   +3 more
wiley   +1 more source

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