Results 51 to 60 of about 1,018,344 (255)

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Absolute intensity of radiation emitted by uranium plasmas [PDF]

open access: yes
The absolute intensity of radiation emitted by fissioning and nonfissioning uranium plasmas in the spectral range from 350 nm to 1000 nm was measured.
Jalufka, N. W.   +2 more
core   +1 more source

Computational Investigation of Microstrip Antennas in Plasma Environment

open access: yes, 2015
Microstrip antennas are extensively used in spacecraft systems and other applications where they encounter a plasma environment. A detailed computational investigation of change in antenna radiation properties in the presence of plasma has been presented
Chaudhury, Bhaskar   +2 more
core   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Ion heating in a plasma focus [PDF]

open access: yes
Ion acceleration and heating in a plasma focus were investigated by the numerical integration of the three-dimensional equations of motion. The electric and magnetic fields given were derived from experimental data.
Gary, S. P., Hohl, F.
core   +1 more source

Effect of Plasma Composition on the Interpretation of Faraday Rotation

open access: yes, 2009
Faraday rotation (FR) is widely used to infer the orientation and strength of magnetic fields in astrophysical plasmas. Although the absence of electron-positron pairs is a plausible assumption in many astrophysical environments, the magnetospheres of ...
Asada   +25 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

A Lumped Parameter Model of Plasma Focus

open access: yesIEEE Transactions on Plasma Science, 2004
In this paper, a fast running computer model of a plasma focus device is presented. The model is based on the snowplow model constructed with effective parameters validated against experimental results. A pinch model is included to calculate the temporal evolution of the focal variables.
Gonzalez, J. H.   +3 more
openaire   +2 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

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