Results 61 to 70 of about 464,123 (264)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Calculation of the Inductance of Plasma Column at PF-1000 Device with Assumed Current Distribution
Acta Polytechnica, 2013 Processed data is taken from the D-D fusion reaction experiments on PF-1000 at IFPILM Warsaw, operating with 2 MA, 1011 neutron yield, using interferometry, temporal resolved neutron diagnostics, magnetic probe diagnostics and X-ray diagnostics.
Jiri Kortanek, Pavel Kubes
doaj
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
On filamentation in the dense plasma focus
Physics of Plasmas, 2022 Striking pictures showing filamentary structures in the plasma focus have intrigued researchers from the early days of plasma focus research. A definitive understanding of their occurrence, origin, structure, and role in plasma focus physics is still not in sight as summarized in a recent comprehensive review.
openaire +2 more sources
FEBS Letters, EarlyView.Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Retraction: Enhancing radiosensitivity of melanoma cells through very high dose rate pulses released by a plasma focus device. [PDF]
PLoS One, 2023 PLOS ONE Editors.
europepmc +1 more source
Acceleration in the plasma focus and in astrophysics
Laser and Particle Beams, 1988 Both, in the laboratory (specifically the plasma focus) and in astrophysics, charges are accelerated in magnetically pinched current channels. The current channels are annular cylinders, defined by an electric double layer of thickness δrE and radius R due to radial polarization of the plasma. The electric field Er in the double layer and the azimuthal
openaire +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source