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Membrane Heterogeneity Beyond the Plasma Membrane [PDF]

open access: yesFrontiers in Cell and Developmental Biology, 2020
The structure and organization of cellular membranes have received intense interest, particularly in investigations of the raft hypothesis. The vast majority of these investigations have focused on the plasma membrane of mammalian cells, yielding ...
Hong-Yin Wang   +3 more
doaj   +3 more sources

Influenza viral infection at the plasma membrane is restricted by lipid composition [PDF]

open access: yesJournal of Virology
Many enveloped viruses enter cells via fusion with the endosomal membrane, raising the question whether entry through the endosomal route confers a fitness advantage over fusion directly at the plasma membrane.
Steinar Mannsverk   +2 more
doaj   +2 more sources

MACROPHAGE PLASMA MEMBRANE [PDF]

open access: yesThe Journal of Experimental Medicine, 1971
Rabbit alveolar macrophages were incubated in vitro with radioactive protein precursors. Plasma membranes were isolated from these cells, dissolved in phenol-urea-acetic acid, and separated by acrylamide gel electrophoresis. 3H-leucine was rapidly incorporated into membrane protein.
Ralph L. Nachman   +2 more
openaire   +2 more sources

Plasma membrane repair [PDF]

open access: yesCurrent Biology, 2018
Tissue wound repair has been studied extensively. It involves the coordinated activation of several intracellular and intercellular pathways, as well as remodeling from the sequential recruitment of different cell types to the wound site. There is, however, an equally important process that happens at the single cell level, when the integrity of the ...
Norma W, Andrews, Matthias, Corrotte
openaire   +2 more sources

Yeast Ist2 recruits the endoplasmic reticulum to the plasma membrane and creates a ribosome-free membrane microcompartment. [PDF]

open access: yesPLoS ONE, 2012
The endoplasmic reticulum (ER) forms contacts with the plasma membrane. These contacts are known to function in non-vesicular lipid transport and signaling.
Wendelin Wolf   +5 more
doaj   +1 more source

Annexin A2 Mediates Dysferlin Accumulation and Muscle Cell Membrane Repair

open access: yesCells, 2020
Muscle cell plasma membrane is frequently damaged by mechanical activity, and its repair requires the membrane protein dysferlin. We previously identified that, similar to dysferlin deficit, lack of annexin A2 (AnxA2) also impairs repair of skeletal ...
Daniel C. Bittel   +7 more
doaj   +1 more source

Therapeutic Nanobodies Targeting Cell Plasma Membrane Transport Proteins: A High-Risk/High-Gain Endeavor

open access: yesBiomolecules, 2021
Cell plasma membrane proteins are considered as gatekeepers of the cell and play a major role in regulating various processes. Transport proteins constitute a subclass of cell plasma membrane proteins enabling the exchange of molecules and ions between ...
Raf Van Campenhout   +4 more
doaj   +1 more source

Critical Role of Lipid Scramblase TMEM16F in Phosphatidylserine Exposure and Repair of Plasma Membrane after Pore Formation

open access: yesCell Reports, 2020
Summary: Plasma membrane damage and cell death during processes such as necroptosis and apoptosis result from cues originating intracellularly. However, death caused by pore-forming agents, like bacterial toxins or complement, is due to direct external ...
Ning Wu   +16 more
doaj   +1 more source

Plasma Membrane Phosphatidylinositol-4-Phosphate Is Not Necessary for Candida albicans Viability yet Is Key for Cell Wall Integrity and Systemic Infection

open access: yesmBio, 2022
Phosphatidylinositol phosphates are key phospholipids with a range of regulatory roles, including membrane trafficking and cell polarity. Phosphatidylinositol-4-phosphate [PI(4)P] at the Golgi apparatus is required for the budding-to-filamentous-growth ...
Rocio Garcia-Rodas   +7 more
doaj   +1 more source

Transport of cholesterol from the endoplasmic reticulum to the plasma membrane is constitutive in CaCo-2 cells and differs from the transport of plasma membrane cholesterol to the endoplasmic reticulum

open access: yesJournal of Lipid Research, 1998
The transport of newly synthesized cholesterol from its site of synthesis, the endoplasmic reticulum, to the plasma membrane was studied in CaCo-2 cells. The appearance of newly synthesized cholesterol on the cell surface was rapid. By 30 min, 50% of the
F. Jeffrey Field   +3 more
doaj   +1 more source

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