Results 111 to 120 of about 1,661,848 (278)
Integration Through Separation – The Role of Lateral Membrane Segregation in Nutrient Uptake
Frontiers in Cell and Developmental Biology, 2019 Nutrient transporters are prominent and ubiquitous components of the plasma membrane in all cell types. Their expression and regulation are tightly linked to the cells’ needs.
Jon V. Busto +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Root growth and signalling: the role of calcium channels [PDF]
, 2017 Roots acquire calcium not only as a macronutrient but also to serve as a second messenger in signalling and a component of exocytosis for growth. Plasma membrane channels are sufficient to deliver calcium from the apoplast to the cytosol to enable its ...
Davies, Julia M.
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PLoS ONE, 2014 BackgroundChloride (Cl) secretion by the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) located in the apical membrane of respiratory epithelial cells plays a critical role in maintenance of the airway surface liquid and mucociliary clearance
Jennifer M Bomberger +5 more
doaj +1 more source
Response of Ustilago maydis against the Stress Caused by Three Polycationic Chitin Derivatives
Molecules, 2017 Chitosan is a stressing molecule that affects the cells walls and plasma membrane of fungi. For chitosan derivatives, the action mode is not clear. In this work, we used the yeast Ustilago maydis to study the effects of these molecules on the plasma ...
Dario Rafael Olicón-Hernández +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
FEBS Open Bio, EarlyView.Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Triacylglycerol-rich lipoprotein cholesterol is derived from the plasma membrane in CaCo-2 cells.
Journal of Lipid Research, 1995 The source for triacylglycerol-rich lipoprotein cholesterol was investigated in CaCo-2 cells grown on filters separating an upper and a lower well. Oleic acid, a fatty acid that promotes triacylglycerol-rich lipoprotein synthesis and secretion in CaCo-2 ...
F.J. Field, E. Born, S.N. Mathur
doaj +1 more source
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
FEBS Open Bio, EarlyView.Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
The septin cytoskeleton facilitates membrane retraction during motility and blebbing. [PDF]
, 2012 Increasing evidence supports a critical role for the septin cytoskeleton at the plasma membrane during physiological processes including motility, formation of dendritic spines or cilia, and phagocytosis.
Chen, Yi-Chun M +3 more
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