Results 231 to 240 of about 4,009,281 (300)

New perspectives on the mechanisms and treatment of valvular heart disease: Mendelian randomization and systematic analysis based on plasma proteins. [PDF]

Medicine (Baltimore)
Wang C, Shao X, Wang J, Shi R, Han M, Feng H, Dong H, Zhang T, Yang W, Deng Y.   +9 more
europepmc   +1 more source

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

Advanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj, Xilal Y. Rima, Kim T. Nguyen, Courtney Culkins, Nana Boateng, Jacob Doon‐Ralls, Alejandro Bresolin, Xin Huang, Hong Li, Vahedi Amid, Ajeet Pal Singh, Dharti Shantaram, Anastasiia Amari, Mangesh D. Hade, Nicholas R. Merriam, Zachary D. Schultz, Scott Q. Harper, Nizar Y. Saad, Setty M. Magaña, Willa A. Hsueh, Rachel E. Kopec, Blaise R. Kimmel, Andre F. Palmer, Eduardo Reátegui   +23 more
wiley   +1 more source

Potential Drug Targets and Causal Plasma Proteins Related to Preeclampsia Identified by Mendelian Randomization. [PDF]

Womens Health Rep (New Rochelle)
Zhou W, Huang T, Li L, Shen Y, Ji Z, Yan M.   +5 more
europepmc   +1 more source

Prostate Cancer Patient‐Derived Organoids (PDOs) as Functional Avatars for Antisense Oligonucleotide (ASO)‐Based Personalized Therapy

Advanced Healthcare Materials, EarlyView.
Prostate patient‐derived organoids (PDOs) were established from TURP and biopsy specimens with >90% success and retain key features of their tissues of origin, making them functional avatars for antisense oligonucleotide (ASO) therapy . Transfecting single cells outside the Matrigel matrix and then reconstituting organoids overcomes the 3D delivery ...
Thi Thom Tran, Thi Tu Uyen Phan, Michael Baboudjian, Quang Hieu Duong, Ines Sousa, Thi Thuy Le, Virginie Baylot, Sophie Giusiano, Laurent Daniel, Pauline Brige, Benjamin Guillet, Cyrille Bastide, Carmen Garrido, David Taïeb, Thi Khanh Le, Palma Rocchi   +15 more
wiley   +1 more source

Blood pressure, plasma proteins, and cardiovascular diseases: a network Mendelian randomization and observational study. [PDF]

Eur Heart J
Meena D, Huang J, Smith A, Yarmolinsky J, Wu S, Koskeridis F, Ko YH, Dib MJ, Antonatos C, Vasilopoulos Y, Yu X, Otto GW, Gill D, Mayr M, Elliott P, Dehghan A, Tzoulaki I.   +16 more
europepmc   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

Comprehensive Analysis of IgA Nephropathy Causal Factors in Plasma Proteins, Immune Cell Types, and Immune Cell Traits. [PDF]

Clin J Am Soc Nephrol
You RL, Liu ZY, Li MS, Li Y, Wang X, Zhou XJ, Zhou XJ, Zhang H.   +7 more
europepmc   +1 more source

The plasma proteins GSN, F2, CRTAC1, and HP reflect multigenerational health, longevity, and resilience

Putter PC, Beekman M, Lakenberg N, Lackmann J, Müller S, Müller R, Deelen J, Slagboom PE, Antczak P, van den Berg NM.   +9 more
europepmc   +1 more source

Long-Term Ambient Benzene Exposure and Brain Disorders Among Urban Adults: Effect Modification by Genetic Susceptibility and Potential Mediation by Plasma Proteins. [PDF]

Adv Sci (Weinh)
Guo J, Zhong X, Koutrakis P, Vieira CLZ, Si F, Wang Y, Lian X, Fan Y, Wang Z, Huang S, Li J.   +10 more
europepmc   +1 more source

Identifying and replicating plasma proteins associated with hypertrophic cardiomyopathy severity in carriers of pathogenic MYBPC3 variants

Hassanzada F, van Vugt M, Jansen M, Baas AF, te Riele AS, Dooijes D, van der Crabben SN, Jongbloed JD, Cox MG, Amin AS, Lekanne Deprez RH, Ruijsink B, Kuster DWD, van der Velden J, Bezzina CR, Asselbergs FW, Peter van Tintelen J, van Spaendonck-Zwarts KY, Schmidt AF.   +18 more
europepmc   +1 more source