Results 81 to 90 of about 3,835,960 (298)

Photoaffinity Labeling of Plasma Proteins

Molecules, 2013
Photoaffinity labeling is a powerful technique for identifying a target protein. A high degree of labeling specificity can be achieved with this method in comparison to chemical labeling.
Masaki Otagiri, Victor Tuan Giam Chuang
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

The plasma proteins: structure, function, and genetic control

, 1975
XVI+436hlm ...
PLASMA PROTEINS, PUTNAM, FRANK W.
core  

Evolution of prokaryotic SPFH proteins. [PDF]

, 2009
BACKGROUND: The SPFH protein superfamily is a diverse family of proteins whose eukaryotic members are involved in the scaffolding of detergent-resistant microdomains. Recently the origin of the SPFH proteins has been questioned.
Reuter Alexander, Markus Hinderhofer, Möller, Heiko M., Möller Heiko M, Hinderhofer Markus, Hinderhofer, Markus, Heiko M Möller, Walker, Christina A, Walker Christina A, Christina A Walker, Stuermer, Claudia AO, Friemel, Anke, Möller, Heiko M, Claudia AO Stuermer, Walker, Christina A., Alexander Reuter, Friemel Anke, Reuter, Alexander, Anke Friemel, Claudia AO Sturmer, Stuermer Claudia AO, Stürmer, Claudia   +21 more
core   +1 more source

Causal inference study of plasma proteins and blood metabolites mediating the effect of obesity-related indicators on osteoporosis

Frontiers in Endocrinology
BackgroundOsteoporosis and obesity are both major global public health problems. Observational studies have found that osteoporosis might be related to obesity. Mendelian randomization (MR) analysis could overcome the limitations of observational studies
Maomao Huang, Maomao Huang, Maomao Huang, Fei Xing, Fei Xing, Yue Hu, Fuhua Sun, Fuhua Sun, Chi Zhang, Chi Zhang, Chi Zhang, Zhangyu Xv, Yue Yang, Qi Deng, Ronglan Shi, Lei Li, Jiayi Zhu, Fangyuan Xu, Dan Li, Dan Li, Jianxiong Wang, Jianxiong Wang, Jianxiong Wang   +22 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Plasma protein biomarkers for depression and schizophrenia by multi analyte profiling of case-control collections. [PDF]

, 2010
Despite significant research efforts aimed at understanding the neurobiological underpinnings of psychiatric disorders, the diagnosis and the evaluation of treatment of these disorders are still based solely on relatively subjective assessment of ...
Brittain, Claire, Holsboer, Florian, Alexander, R. C., Inga Prokopenko, Robert C Alexander, Rujescu, D., Enrico Domenici, Bullmore, E., Giegling, Ina, Tozzi, F., Claire Brittain, Prokopenko, I, Turck, C., Ina Giegling, Merlo-Pich, E, Middleton, Lefkos, Wille, DR, Tozzi, Federica, Domenici, Enrico, Merlo-Pich, Emilio, Willé, David R., Miller, Sam, Astrid McKeown, Domenici, E, Edward T Bullmore, Middleton, L, Bullmore, ET, Alexander, Robert C., Tozzi, F, Robert C. Alexander, Holsboer, F, Emilio Merlo-Pich, Merlo-Pich, E., Rujescu, D, Sam Miller, McKeown, A, Middleton, L., Christoph W Turck, Federica Tozzi, Enrico Domenici, Prokopenko, I., Wille, D., David R Willé, Pierandrea Muglia, Giegling, I, McKeown, A., Turck, CW, Holsboer, F., Dan Rujescu, Bullmore, Edward T., Wille, D. R., Brittain, C, Christoph W. Turck, McKeown, Astrid, Muglia, P, Alexander, RC, Prokopenko, Inga, Miller, S., Giegling, I., Alexander, R., Muglia, P., Bullmore, E. T., David R. Willé, Edward T. Bullmore, Muglia, Pierandrea, Turck, C. W., Florian Holsboer, Brittain, C., Miller, S, Lefkos Middleton, Domenici, E., Turck, Christoph W., Rujescu, Dan   +72 more
core   +1 more source

Anti-inflammatory effects of animal plasma protein supplementation in mice undergoing simultaneous gut and lung inflammation

Food and Agricultural Immunology, 2020
We aimed to determine whether dietary supplementation with spray-dried porcine plasma (SDP) is effective in mice exposed to a dual S. aureus enterotoxin B (SEB) and lipopolysaccharide (LPS) challenges inducing simultaneous inflammation in the gut and ...
L. Miró, C. Amat, J. Polo, M. Moretó, A. Pérez-Bosque   +4 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Trends in Protein-Based Biosensor Assemblies for Drug Screening and Pharmaceutical Kinetic Studies

Molecules, 2014
The selection of natural and chemical compounds for potential applications in new pharmaceutical formulations constitutes a time-consuming procedure in drug screening. To overcome this issue, new devices called biosensors, have already demonstrated their
Ana M. Gonçalves, Augusto Q. Pedro, Fátima M. Santos, Luís M. Martins, Cláudio J. Maia, João A. Queiroz, Luís A. Passarinha   +6 more
doaj   +1 more source