Results 111 to 120 of about 391,649 (370)

Sodium chloride versus glucose solute as a volume replacement therapy for more effective decongestion in acute heart failure (SOLVRED‐AHF): A prospective, randomized, mechanistic study

European Journal of Heart Failure, EarlyView.
The impact of sodium chloride (NaCl) supplementation on proximal and distal tubular reabsorption in acute heart failure (AHF). Abstract Aims We questioned the long‐standing paradigm that sodium/chloride restriction is essential for effective decongestion in acute heart failure (AHF). This study compared the decongestive effects of two isotonic infusion
Jan Biegus, Gracjan Iwanek, Jeffrey Testani, Robert Zymliński, Marat Fudim, Mateusz Guzik, Piotr Gajewski, Piotr Ponikowski   +7 more
wiley   +1 more source

Racial differences in sensitivity of blood pressure to aldosterone [PDF]

, 2014
Blacks in comparison with whites are at risk for a more serious form of hypertension with high rates of complications. Greater sodium retention is thought to underlie the blood pressure (BP)-determining physiology of blacks, but specific mechanisms have ...
Dimeglio, Linda A., Eckert, George J., Hannon, Tamara S., Jung, Jeesun, Liu, Hai, Pratt, J. Howard, Pratt, Linda M., Tu, Wanzhu, Wagner, Mary Anne   +8 more
core   +1 more source

The novel serine protease PreR-Co promotes endothelium-independent vasorelaxation in rabbit aortic rings [PDF]

, 2003
The effect of a novel enzyme (PreR-Co) that activates renal prorenin was studied on rabbit aortas with and without endothelium. It was tested 1) in the basal tone of nonstimulated or ANG II-sensitized rings or rings precontracted with norepinephrine (NE),
Coviello, Alfredo, de Vito, Eduardo, Guardia, Dora Cecilia, Peral, Maria de Los Angeles, Romano, Monica Liliana, Vincent, Paula Andrea   +5 more
core   +1 more source

Medication adherence in patients with acutely decompensated heart failure: A cross‐sectional study in the emergency department (ADHF‐ED)

European Journal of Heart Failure, EarlyView.
The ADHF‐ED trial. ADHF, acutely decompensated heart failure; CHF, chronic heart failure; ED, emergency department; EF, ejection fraction; MRA, mineralocorticoid receptor antagonist; NT‐proBNP, N‐terminal pro‐B‐type natriuretic peptide. Created with the support of AI (ChatGPT).
Michael Kunz, Juel Maalouli Schaar, Katharina R. Welker, Lucas Lauder, Felix Götzinger, Ingrid Kindermann, Martin Schulz, Michael Böhm, Markus R. Meyer, Felix Mahfoud   +9 more
wiley   +1 more source

Improving Activity of ACE Inhibitory Peptide by Sequence‐Based Rational Design: Properties, Function on Endothelial Cells, and Potential Antihypertensive Mechanism

Food Frontiers, EarlyView.
The process diagram of this study develops the ACE inhibitory peptide by sequence‐based design and investigates its properties, functions on endothelial cells, and potential antihypertensive action mechanism. ABSTRACT The comprehension of the relationship between structure and function and mechanisms of intermolecular interactions within amino acid ...
Qingping Liang, Zhemin Liu, Mengshi Xiao, Wei Zhou, Dongxing Yu, Jiaming Liu, Le Wang, Haijin Mou   +7 more
wiley   +1 more source

The renin angiotensin system in the development of cardiovascular disease: role of aliskiren in risk reduction

Vascular Health and Risk Management, 2008
Paolo Verdecchia1, Fabio Angeli1, Giovanni Mazzotta1, Giorgio Gentile2, Gianpaolo Reboldi21Department of Cardiology, Clinical Research Unit ‘Preventive Cardiology’, Hospital ‘Santa Maria della Misericordia’, and Fondazione Umbra ...
Paolo Verdecchia, Fabio Angeli, Giovanni Mazzotta, Giorgio Gentile, Gianpaolo Reboldi   +4 more
doaj  

Hypertension in mice lacking 11beta-hydroxysteroid dehydrogenase type 2 [PDF]

, 1999
Deficiency of 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) in humans leads to the syndrome of apparent mineralocorticoid excess (SAME), in which cortisol illicitly occupies mineralocorticoid receptors, causing sodium retention, hypokalemia, and ...
Arriza, Benediktsson, Berl, Brown, Brown, Chomczynski, Christopher Kenyon, Christopher R.W. Edwards, Clark, Cole, Edwards, Fleming, Gordon, Grone, Grunder, Guyton, Jamieson, John J. Mullins, Jonathan R. Seckl, Kaissling, Kotelevtsev, Krozowski, Lifton, Lindsay, Low, Millar, Mune, Nehls, Roger W. Brown, Sharp, Shimkets, Simon, Stewart, Stewart, Stewart, Stewart Fleming, Ulick, White, White, Yuri Kotelevtsev   +39 more
core   +3 more sources

Things We Do for No Reason: Failing to consider primary aldosteronism in the initial evaluation of hypertension, hypertensive urgency, and hypertensive emergency

Journal of Hospital Medicine, EarlyView.
Abstract Hypertension is frequently treated as essential hypertension. However, secondary causes of hypertension should be considered, because distinct treatments are used for different causes of hypertension. Primary aldosteronism is considered a candidate for the most common cause of secondary hypertension.
Michael C. Shih, Tessa R. Lavorgna, Prerna Dogra, Christina N. Hirner, Kristen Payne   +4 more
wiley   +1 more source

Arterial hypertension in patients with systemic connective tissue diseases and hemorrhagic vasculitis

Терапевтический архив, 2010
Aim. To study the specific features of 24-hour blood pressure (BP) profile and its association with plasma renin activity in patients with systemic connective tissue diseases and hemorrhagic vasculitis (HV). Subjects and methods.
Nataliya Petrovna Shilkina, Igor' Evgen'evich Yunonin, Svetlana Anatol'evna Stolyarova, Irina Valentinovna Dryazhenkova, N P Shilkina, I E Yunonin, S A Stolyarova, I V Dryazhenkova   +7 more
doaj  

Juxtaglomerular cell tumor: a case report

Journal of Medical Case Reports
Introduction The tumor produces an excessive amount of renin resulting in secondary hyperaldosteronism, thereby causing hypertension with hypokalemia. The authors describe a case of reninoma in a young man, who presented with malignant hypertension. Case
Kays Chaker, Syrine Tlili, Alia Zehani, Nader Gharbia, Mariem Snoussi, Wassim Frikha, Hiba Ghabi, Boutheina Mosbahi, Ikram Mami, Mohamed Karim Zouaghi, Yassine Nouira   +10 more
doaj   +1 more source