Characteristics of aldosterone-producing adenomas in patients without plasma renin activity suppression. [PDF]
Kubo H+16 more
europepmc +1 more source
We aimed to examine the effects of a sodium glucose co-transporter 2 (SGLT2) inhibitor on systemic and intrarenal renin–angiotensin system (RAS) in subtotally nephrectomized non-diabetic rats, a model of chronic kidney disease (CKD).
Lei Li+10 more
doaj
Prevalence of Metabolic‐Associated Steatotic Liver Disease in Patients With Primary Aldosteronism
ABSTRACT Objective To assess the prevalence of metabolic associated steatotic liver disease (MASLD) in patients with primary aldosteronism (PA) compared to benign adrenal adenomas, and to evaluate the impact of hormonal excess in inducing MASLD. Design Single‐centre retrospective study. Methods Hepatic steatosis was assessed by liver/spleen (L/S) ratio
Irene Tizianel+6 more
wiley +1 more source
Is It Possible to Screen for Primary Aldosteronism Effectively in Primary Care?
ABSTRACT Objective Primary aldosteronism (PA) is the commonest secondary cause of hypertension but case‐detection remains a challenge. Screening is usually performed in secondary care using an aldosterone:renin ratio (ARR) measurement. Here, we describe the outcomes of screening in primary care, in Oxfordshire, UK.
Harsha Anuruddhika Dissanayake+9 more
wiley +1 more source
Plasma renin activity variation following admission predicts patient outcome in acute decompensated heart failure with reduced and mildly reduced ejection fraction. [PDF]
Azuma K+10 more
europepmc +1 more source
The Role of Renal Nerves and Prostaglandins in Control of Renal Hemodynamics and Plasma Renin Activity during Hypotensive Hemorrhage in the Dog [PDF]
William L. Henrich+6 more
openalex +1 more source
Organoid Models to Study Human Infectious Diseases
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu+4 more
wiley +1 more source
Plasma Renin Activity: A Method for Rapid Screening by Radioimmunoassay and a Comparison of Two Commercially Available Kits [PDF]
Samuel D. Goldberg, F W Spierto
openalex +1 more source
Targeting Regulation of Macrophage to Treat Metabolic Disease: Role of Phytochemicals
One‐third of the world's population is affected by metabolic syndrome. Complicated pathogenesis and limited drugs cause the growing prevalence of metabolic syndrome. Macrophage‐mediated metaflammation is closely associated with the development of metabolic syndrome. The role of phytochemicals targeting macrophages in the treatment of metabolic syndrome
Zeting Ye+6 more
wiley +1 more source
Obesity‐related glomerulopathy: How it happens and future perspectives
Abstract Obesity‐related glomerulopathy (ORG) is an emerging complication of excess adiposity. Its incidence rises alongside the obesity pandemic. Up to 40% of individuals can be affected by ORG, irrespective of the status of glomerular filtration rate and albuminuria.
Jian‐Wen Samuel Lee‐Boey+7 more
wiley +1 more source