Results 121 to 130 of about 207,763 (300)

Characteristics of aldosterone-producing adenomas in patients without plasma renin activity suppression. [PDF]

open access: yesPLoS One, 2022
Kubo H   +16 more
europepmc   +1 more source

Effect of a SGLT2 inhibitor on the systemic and intrarenal renin–angiotensin system in subtotally nephrectomized rats

open access: yesJournal of Pharmacological Sciences, 2018
We aimed to examine the effects of a sodium glucose co-transporter 2 (SGLT2) inhibitor on systemic and intrarenal renin–angiotensin system (RAS) in subtotally nephrectomized non-diabetic rats, a model of chronic kidney disease (CKD).
Lei Li   +10 more
doaj  

Prevalence of Metabolic‐Associated Steatotic Liver Disease in Patients With Primary Aldosteronism

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Objective To assess the prevalence of metabolic associated steatotic liver disease (MASLD) in patients with primary aldosteronism (PA) compared to benign adrenal adenomas, and to evaluate the impact of hormonal excess in inducing MASLD. Design Single‐centre retrospective study. Methods Hepatic steatosis was assessed by liver/spleen (L/S) ratio
Irene Tizianel   +6 more
wiley   +1 more source

Is It Possible to Screen for Primary Aldosteronism Effectively in Primary Care?

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Objective Primary aldosteronism (PA) is the commonest secondary cause of hypertension but case‐detection remains a challenge. Screening is usually performed in secondary care using an aldosterone:renin ratio (ARR) measurement. Here, we describe the outcomes of screening in primary care, in Oxfordshire, UK.
Harsha Anuruddhika Dissanayake   +9 more
wiley   +1 more source

Plasma renin activity variation following admission predicts patient outcome in acute decompensated heart failure with reduced and mildly reduced ejection fraction. [PDF]

open access: yesHeliyon, 2023
Azuma K   +10 more
europepmc   +1 more source

The Role of Renal Nerves and Prostaglandins in Control of Renal Hemodynamics and Plasma Renin Activity during Hypotensive Hemorrhage in the Dog [PDF]

open access: bronze, 1978
William L. Henrich   +6 more
openalex   +1 more source

Organoid Models to Study Human Infectious Diseases

open access: yesCell Proliferation, EarlyView.
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu   +4 more
wiley   +1 more source

Targeting Regulation of Macrophage to Treat Metabolic Disease: Role of Phytochemicals

open access: yesCell Proliferation, EarlyView.
One‐third of the world's population is affected by metabolic syndrome. Complicated pathogenesis and limited drugs cause the growing prevalence of metabolic syndrome. Macrophage‐mediated metaflammation is closely associated with the development of metabolic syndrome. The role of phytochemicals targeting macrophages in the treatment of metabolic syndrome
Zeting Ye   +6 more
wiley   +1 more source

Obesity‐related glomerulopathy: How it happens and future perspectives

open access: yesDiabetic Medicine, EarlyView.
Abstract Obesity‐related glomerulopathy (ORG) is an emerging complication of excess adiposity. Its incidence rises alongside the obesity pandemic. Up to 40% of individuals can be affected by ORG, irrespective of the status of glomerular filtration rate and albuminuria.
Jian‐Wen Samuel Lee‐Boey   +7 more
wiley   +1 more source

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