Results 131 to 140 of about 391,649 (370)

Temporal changes in cardiac oxidative stress, inflammation and remodeling induced by exercise in hypertension: Role for local angiotensin II reduction [PDF]

, 2017
Exercise training reduces renin-angiotensin system (RAS) activation, decreases plasma and tissue oxidative stress and inflammation in hypertension. However, the temporal nature of these phenomena in response to exercise is unknown. We sought to determine
Casarini, Dulce E., Jara, Zaira P., Lima, Larissa S., Michelini, Lisete C., Montezano, Augusto C., Peres, Roseli, Scavone, Cristóforo, Silva, Sebastião D., Touyz, Rhian M   +8 more
core   +3 more sources

The flat glucose response curve during oral glucose tolerance tests in Chinese pregnant women and its association with adverse outcomes

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
A flat OGTT curve during pregnancy is associated with lower birth weight, and decreased risks of large for gestational age infants, macrosomia, gestational hypertension, and preeclampsia. Moreover, these risks varied based on maternal age and preconception BMI.
Ya Xi, Qianqian Wu, Binbin Yin, Jinghua Zhang, Yongying Bai   +4 more
wiley   +1 more source

The Postural Tachycardia Syndrome (POTS): Pathophysiology, Diagnosis & Management [PDF]

, 2006
Postural tachycardia syndrome (POTS), characterized by orthostatic tachycardia in the absence of orthostatic hypotension, has been the focus of increasing clinical interest over the last 15 years 1. Patients with POTS complain of symptoms of tachycardia,
Raj, Satish R
core   +1 more source

Targeting acetylated high mobility group box 1 protein (HMGB1) and toll‐like receptor (TLR4) interaction to alleviate hypertension and neuroinflammation in fructose‐fed rats

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Our previous study reported that fructose intake increased systemic blood pressure and reduced nitric oxide (NO) in the nucleus tractus solitarius (NTS) due to oxidative stress and neuroinflammation. However, it remains unclear how reactive oxygen species (ROS) reduce NO and how this process impacts neuroinflammation in ...
Yu‐Te Lin, Chiu‐Yi Ho, Gwo‐Ching Sun, Tzyy‐Yue Wong, Michael Hsiao, Ching‐Jiunn Tseng, Pei‐Wen Cheng   +6 more
wiley   +1 more source

The effect of potassium loading on sodium excretion and plasma renin activity in Addisonian man. [PDF]

, 1975
Paul D. Miller, Catheryne Waterhouse, Robyn Owens, Edwin Cohen   +3 more
openalex   +1 more source

Stabilisation of PRCP by deubiquitinase‐targeting chimera (DUBTAC) to replenish autophagy for ameliorating pathological cardiac hypertrophy

British Journal of Pharmacology, EarlyView.
Background and Purpose Autophagy is essential for cellular homeostasis, and its impairment contributes to cardiac hypertrophy. Modulating autophagy has shown potential in treating pathological hypertrophy. Prolylcarboxypeptidase (PRCP), a lysosomal enzyme that hydrolyzes angiotensin II to Ang1‐7, has an unclear role in cardiac autophagy and hypertrophy.
Fangchao Zhou, Jun Xia, Yingjuan Liu, Wenqi He, Hongyuan Zhang, Bernard D. Keavney, Min Zi, Binh Y. Nguyen, Tamer M. A. Mohamed, Jessica M. Miller, Riham R. E. Abouleisa, Susanne S. Hille, Elizabeth J. Cartwright, Oliver J. Müller, Honglin Xu, Sam Butterworth, Xin Wang   +16 more
wiley   +1 more source

Adiposity, aldosterone and plasma renin activity among African Americans: The Jackson Heart Study. [PDF]

Endocr Metab Sci, 2023
Lee G, Kluwe B, Zhao S, Kline D, Nedungadi D, Brock GN, Odei JB, Kesireddy V, Pohlman N, Sims M, Effoe VS, Wu WC, Kalyani RR, Wand GS, Echouffo-Tcheugui J, Golden SH, Joseph JJ.   +16 more
europepmc   +1 more source

Plasma Renin Activity: A Method for Rapid Screening by Radioimmunoassay and a Comparison of Two Commercially Available Kits [PDF]

, 1973
Samuel D. Goldberg, F W Spierto
openalex   +1 more source

Targeting dipeptidyl peptidase 3 (DPP3) in extreme‐critically ill patients with refractory shock: First‐in‐human report on the safety and efficacy of an anti‐DPP3 antibody

European Journal of Heart Failure, EarlyView.
Dominik Jarczak, Axel Nierhaus, Alexandre Mebazaa, Antoine Herpain, Peter Pickkers, Sanchir Anar, Stefan Kluge   +6 more
wiley   +1 more source

The thoracic perivascular adipose tissue spontaneously induces vasoconstriction through activation of α1‐adrenoceptors

British Journal of Pharmacology, EarlyView.
Background and Purpose Although perivascular adipose tissue (PVAT) contains substances with contractile properties, its actions on the vascular tone are associated with the release of anticontractile substances. We hypothesize that procontractile PVAT products also exert direct effects on vascular tone. Experimental Approach Thoracic aortas from Wistar
Leonardo Gomes‐Pereira, José Eduardo da Silva‐Santos   +1 more
wiley   +1 more source