Results 141 to 150 of about 550,587 (345)

Healthy Aging Metabolomic and Proteomic Signatures Across Multiple Physiological Compartments

open access: yesAging Cell, EarlyView.
The association of the aging scores with the clinical covariates suggests increased inflammation, strong predisposition to iron deficiency anemia, decline in muscle mass, and renal and hepatic functions with accelerated aging. ABSTRACT The study of biomarkers in biofluids and tissues expanded our understanding of the biological processes that drive ...
R. Moaddel   +17 more
wiley   +1 more source

SYMPATHO-ADRENAL SYSTEM IN ARTERIAL HYPERTENSION PATIENTS: ACTIVITY ASSESSMENT AND CLINICAL VALUE

open access: yesРоссийский кардиологический журнал, 2009
The study was focused on assessing sympatho-adrenal system (SAS) activity in patients with arterial hypertension and included 454 hypertensive individuals at high risk.
Sh. V. Akhadov   +4 more
doaj  

Low plasma renin activity is associated with "Apparently" idiopathic atrial fibrillation. [PDF]

open access: yesInt J Cardiol Heart Vasc, 2023
Shen Y, Ma G, Sun M, Li M, Chen M.
europepmc   +1 more source

Dietary Restriction Mitigates Vascular Aging, Modulates the cGAS‐STING Pathway and Reverses Macrophage‐Like VSMC Phenotypes in Progeroid DNA‐Repair‐Deficient Ercc1Δ/− Mice

open access: yesAging Cell, EarlyView.
Dietary restriction mitigates vascular aging in DNA‐repair‐deficient Ercc1Δ/− mice by reducing extracellular matrix remodeling, inflammation, oxidative stress, and switching of vascular smooth muscle cells to a macrophage‐like phenotype. Our findings suggest that the cGAS‐STING pathway plays a key role in vascular aging and that the benefits of dietary
S. J. M. Stefens   +14 more
wiley   +1 more source

Effects of empagliflozin on cardiorespiratory fitness and significant interaction of loop diuretics [PDF]

open access: yes, 2018
The effects of empagliflozin on cardiorespiratory fitness in patients with type 2 diabetes mellitus (T2DM) and heart failure with reduced ejection fraction (HFrEF) are unknown.
Abbate   +14 more
core   +2 more sources

Long‐term alcohol consumption and incident health risk conditions related to cardiometabolic risk markers: A 20‐year prospective cohort study

open access: yesAddiction, EarlyView.
Abstract Background and aims Amid questions about a perceived association between low‐to‐moderate alcohol consumption and reduced cardiovascular risk from recent studies, research examining the impact of alcohol consumption on cardiometabolic risk markers has reported inconsistent results.
Sooyeun Choi, Taeyoung Park, Youjin Je
wiley   +1 more source

ADH Levels during Salt Depletion in Dogs * [PDF]

open access: yes, 1971
Two groups of trained dogs were subjected to sodium chloride depletion and plasma ADH concentration, renin activity, plasma sodium, plasma osmolality, blood volume, hematocrit and body weight were measured.
Bonjour, Jean-Philippe   +2 more
core   +1 more source

The dark sides of the GPCR tree ‐ research progress on understudied GPCRs

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract A large portion of the human GPCRome is still in the dark and understudied, consisting even of entire subfamilies of GPCRs such as odorant receptors, class A and C orphans, adhesion GPCRs, Frizzleds and taste receptors. However, it is undeniable that these GPCRs bring an untapped therapeutic potential that should be explored further.
Magdalena M. Scharf   +10 more
wiley   +1 more source

Gender differences renin-angiotensin-aldosterone system and its relation to humoral factors in patients with arterial hypertension [PDF]

open access: yesСистемные гипертензии, 2015
Aim. Explore gender characteristics of the renin-angiotensin-aldosterone system (RAAS), to assess the state of the RAAS relationship with the level of female sex hormones, aldosterone, plasma renin activity in patients with arterial hypertension (AH) in ...
G M Dadashova
doaj  

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