Results 261 to 270 of about 93,450 (318)
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Radioimmunoassay of plasma renin activity
Seminars in Nuclear Medicine, 1975Plasma renin activity is quantitated by measuring the rate of angiotensin generation during incubation of plasma renin with endogenous renin substrate. The angiotensin is quantitated by radioimmunoassay. Our studies indicate that the incubation step is best carried out in undiluted plasma at the pH optimum for renin (pH 5.7) in the presence of EDTA ...
J E, Sealey, J H, Laragh
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Activation of Rat Plasma Renin*
Endocrinology, 1981Three distinct molecular weight species of active renin, with apparent molecular weights of more than 150,000, 65,000, and 43,000 are present in the plasma of conscious rats. After acute in vivo renin stimulation (ether anesthesia and hemorrhage), however, only the low molecular weight form could be detected.
J D, Barrett, P, Eggena, M P, Sambhi
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Plasma renin activity in hypertension
The American Journal of Medicine, 1967Abstract Plasma renin activity was measured in 115 patients with hypertension. Increased plasma renin activity is consistently observed in patients with malignant hypertension and in patients in whom the serum sodium is depressed. Except in such patients, increased plasma renin activity is uncommon in hypertension and has little diagnostic or ...
M C, Creditor, U K, Loschky
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Plasma Renin Activity in Abortion
Acta Obstetricia et Gynecologica Scandinavica, 1976Abstract. Healthy women (N = 96) were investigated for changes in plasma renin activity (PRA) in abortion. In spontaneous abortion PRA levels were significantly lower than in induced abortion although higher than in healthy women. These findings may be explained by differences in corpus luteum function and renin production of the fetoplacental unit ...
P, Soveri, F, Fyhrquist, O, Widholm
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Normal Plasma Renin Activity in Low Renin Hypertension
The Journal of Clinical Endocrinology & Metabolism, 1975Plasma renin activity (PRA) was measured every 4 h during a 24-h period of continuous recumbency in 10 patients with essential hypertension. All had maximum values at 12 midnight, 4 AM or 8 AM. Analysis of our date and that of others indicates that in some patients with "low renin" hypertension (LRH) these noctural peaks are of normal magnitude ...
R S, Modlinger, M, Gutkin
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Immunoradiometric Assay of Active Renin in Human Plasma: Comparison with Plasma Renin Activity
Clinical and Experimental Hypertension. Part A: Theory and Practice, 1987The direct measurement of active renin with monoclonal antibodies (IRMA) in plasma from hypertensive patients was compared with the traditional PRA method. Two monoclonal antibodies were used: 3E8 and 4G1. The first was coupled to magnetizable beads and was used to trap both active and inactive renin from plasma. The second antibody, 4G1, was iodinated
P, Dessì-Fulgheri +5 more
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PLASMA RENIN ACTIVITY IN CHRONIC NEPHROPATHY
Acta Medica Scandinavica, 1970Abstract. Plasma renin activity (PRA) has been measured in 14 patients with chronic nephropathy maintained on hemodialysis. Most of the patients were hypertensive at the time of measurement, and mean PRA was significantly elevated. No correlation between PRA, mean blood pressure and dialytic controllability of hypertension could be established.
I, Nielsen, E, Clausen, G, Jensen
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Plasma renin activity in renovascular hypertension
The American Journal of Medicine, 1968Abstract Plasma renin activity was measured in forty-eight hypertensive patients with angiographie evidence of unilateral or bilateral occlusive disease of a main stem renal artery. Increased plasma renin activity in patients with unilateral renal arterial lesions was almost always (96 per cent) predictive of a satisfactory response to subsequent and ...
N M, Bath, J C, Gunnells, R R, Robinson
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RADIOIMMUNOASSAY DETERMINATION OF PLASMA-RENIN ACTIVITY
The Lancet, 1969Abstract Both practical and theoretical considerations have made difficult the application of a recently developed angiotensin II immunoassay to the measurement of " plasma-renin activity ", and a separate radioimmunoassay for angiotensin I has therefore been developed.
G W, Boyd +3 more
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Plasma renin activity during ovine pregnancy
American Journal of Physiology-Legacy Content, 1975Chronic intravascular catheterization in maternal, fetal, and neonatal sheep was utilized to assess basal plasma renin activity (PRA) and changes in PRA in response to furosemide. Maternal PRA increased from base-line levels during the last trimester of pregnancy and remained elevated for 12 wk postpartum.
A R, Fleischman +4 more
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