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Plasma Renin Activity in Diabetes Mellitus
Clinical Science, 19791. The plasma renin activity (PRA) was measured in 76 diabetic patients who were attending an outpatients clinic. Of these patients 16 had untreated hypertension and 28 had diabetic complications, which ranged from microaneurysms to renal failure and blindness. 2.
A C, Burden, H, Thurston
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Measurement of Plasma Renin Activity
2013This chapter describes the measurement of plasma renin activity by calculation of the quantity of angiotensin I that is released in plasma by the action of endogenous enzyme renin on angiotensinogen, the endogenous substrate. Details are given for the generation of angiotensin I from plasma using controlled pH and temperature conditions.
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1994
Renin is a proteolytic enzyme (M.Wt. 40 kDa) released by the juxtaglomerular cells of the kidney in response to sympathetic neural activity, dehydration, or salt loss.
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Renin is a proteolytic enzyme (M.Wt. 40 kDa) released by the juxtaglomerular cells of the kidney in response to sympathetic neural activity, dehydration, or salt loss.
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Plasma Renin Activity and Cardiovascular Disease
Clinical Science, 19741. A group of patients with essential hypertension was divided into three categories on the basis of the plasma renin activity. 2. There was no correlation between the plasma renin activity categorized as high, normal or low and the duration of hypertension, the incidence of left ventricular enlargement, the blood urea nitrogen, serum ...
R B, Hickler +3 more
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Measurement of Plasma Renin Activity
2006Measurement of angiotensin 1, released in plasma by the action of endogenous enzyme renin on endogenous substrate, angiotensinogen is described. Details are given for the generation of angiotensin 1 from plasma using controlled conditions of pH and temperature.
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Hypothalamic control of plasma renin activity
Pflügers Archiv European Journal of Physiology, 1977The participation of the hypothalamus in the regulation of plasma renin activity (PRA) in rats was studied by applying electric stimulation to the supramammilar region (50 Hz, 1 ms, 150 muA), general hypoxia (90% N2 + 10% O2), and hypovolemia (peritoneal dialysis with 5.5% glucose) as stimuli of renin secretion.
N, Natcheff, A, Logofetov, N, Tzaneva
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PLASMA RENIN ACTIVITY IN WILMS' TUMOUR
Acta Endocrinologica, 1971ABSTRACT Plasma renin activity (PRA) was measured by means of a radioimmunoassay for angiotensin I in 8 children with Wilms' tumour and in 12 normal children. Blood pressure in the patients was in the upper range of normal or just above. Before nephrectomy PRA levels were significantly higher than in normal children and adults.
P A, Voûte +2 more
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Plasma Cryoactivated Renin and Active Renin in Diabetes Mellitus*
The Journal of Clinical Endocrinology & Metabolism, 1981PRA and the inactive renin which is activated by cold (IR-C) were studied in a group of normal subjects and in patients with diabetes mellitus with and without the presence of nephropathy. The amount of renin activity, as measured after incubation of plasma at -5 C for 4 days, was called cold renin activity (CR.
M R, Manchandia +3 more
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Renin‐activation by kallikrein: evidence for alkaline‐activation of plasma renin
European Journal of Clinical Investigation, 1979Abstract. Porcine pancreatic kallikrein leads to a significant activation of human plasma renin when incubated at pH 8·2. ‘Endogenous’ activation of plasma renin can be seen by incubation of plasmas at the same pH. Both ‘endogenous’ alkaline‐ and kallikrein‐activation of plasma renin can be inhibited by aprotinin.
W, Hummerich +4 more
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