Results 61 to 70 of about 93,450 (318)

The effect of aspirin therapy on the plasma renin activity in myocardial infarction [PDF]

Journal of Kerman University of Medical Sciences, 1995
In this study, the changes of renin system activity and the effects of aspirin therapy on the plasma renin activity ( PRA) in myocardial infarction were investigated. Fifty nine patients with myocardial infarction were selected.
M.H Ansari, F GHavam, A Rashidi, K Etemad   +3 more
doaj  

Sex differences in soluble prorenin receptor in patients with type 2 diabetes

Biology of Sex Differences, 2021
Background The soluble prorenin receptor (sPRR), a member of the renin-angiotensin system (RAS), is elevated in plasma of patients with preeclampsia, hypertension, chronic kidney disease (CKD), and type 2 diabetes.
Bruna Visniauskas, Danielle Y. Arita, Carla B. Rosales, Mohammed A. Feroz, Christina Luffman, Michael J. Accavitti, Gabrielle Dawkins, Jennifer Hong, Andrew C. Curnow, Tina K. Thethi, John J. Lefante, Edgar A. Jaimes, Franck Mauvais-Jarvis, Vivian A. Fonseca, Minolfa C. Prieto   +14 more
doaj   +1 more source

Direct Renin Assay and Plasma Renin Activity Assay Compared [PDF]

Clinical Chemistry, 2004
The enzyme renin ( M r ∼40 000) is released in an active form from the renal juxtaglomerular cells in response to physiologic factors, including sodium depletion, decreased blood volume and blood pressure, and β-adrenergic stimulation (1). Although several local angiotensin II-generating systems exist within various tissues (including the heart, brain,
Deirdré, Hartman, Giuseppe A, Sagnella, Christine A, Chesters, Graham A, Macgregor   +3 more
openaire   +2 more sources

Cardiovascular‐Kidney‐Metabolic Syndrome in People With HIV: An Emerging Frontier for Clinical Pharmacology

Clinical Pharmacology &Therapeutics, EarlyView.
As antiretroviral therapy (ART) prolongs lifespans, people with HIV (PWH) face a new syndemic: Cardiovascular‐Kidney‐Metabolic (CKM) syndrome. Yet CKM in PWH is poorly characterized. Inflammation, complex pharmacokinetic (PK) alterations, ART‐associated metabolic effects, and gut dysbiosis amplify risk. Managing CKM increases medication burden, thereby
Aaron S. Devanathan, Thomas D. Nolin
wiley   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Relationship between Plasma Aldosterone Levels and Left Ventricular Mass in Hypertensive Africans

International Journal of Hypertension, 2013
Background. Hypertension is the most common cardiovascular disease worldwide and is a major cause of morbidity and mortality. Studies have suggested that the activity of the renin-angiotensin-aldosterone system play a major role in the target organ ...
Adewole Adebiyi, Olubayo Akinosun, Chibuike Nwafor, Ayodele Falase   +3 more
doaj   +1 more source

Influence of antihypertensive therapy, sodium intake and the concentration of potassium in plasma on concentration of aldosterone and plasma renin activity [PDF]

Medicinski Glasnik Specijalne Bolnice za Bolesti Štitaste Žlezde i Bolesti Metabolizma "Zlatibor", 2013
Introduction: Primary aldosteronism (PA) is a group of disorders which are characterized by inadequate and non-suppressible production of aldosterone. The prevalence of PA is increasing in hypertensive population.
Lalić Tijana
doaj   +1 more source

Meta‐analysis of sotagliflozin, a dual sodium‐glucose‐cotransporter 1/2 inhibitor, for heart failure in type 2 diabetes

ESC Heart Failure, Volume 12, Issue 2, Page 968-979, April 2025.
Abstract Sodium‐glucose co‐transporters (SGLTs) mediate sodium and glucose transport across cell membranes. SGLT2 inhibitors have a recognized place within heart failure (HF) guidelines. We evaluated the effect of sotagliflozin on HF and cardiovascular outcomes in participants with type 2 diabetes. Scopus, Medline, Embase and Central were searched from
Maria Anna Bantounou, Panagiotis Sardellis, Josip Plascevic, Ribeya Awaes‐Mahmood, Justyna Kaczmarek, Daniel Black Boada, Rosa Thuemmler, Sam Philip   +7 more
wiley   +1 more source

Twenty-Four-Hour Urinary Aldosterone Predicts Inappropriate Left Ventricular Mass Index in Patients with Primary Aldosteronism

The Scientific World Journal, 2013
Objective. Primary aldosteronism (PA) is associated with inappropriate left ventricular hypertrophy (LVH) in relation to a given gender and body size. There is no ideal parameter to predict the presence of LVH or inappropriate LVH in patients with PA. We
Chi-Sheng Hung, Yi-Lwun Ho, Yi-Yao Chang, Vin-Cent Wu, Xue-Ming Wu, Jen-Kuang Lee, Shih-Chieh Chueh, Yen-Hung Lin, Yuan-Shian Changh, Shao-Yu Yang, Ya-Hui Hu, Ming-Jai Sui, Ming-Fong Chen, Kwan-Dun Wu   +13 more
doaj   +1 more source

N‐terminal pro‐brain natriuretic peptide and cardiorenal outcome in patients with anaemia in chronic kidney disease

ESC Heart Failure, Volume 12, Issue 2, Page 848-858, April 2025.
Abstract Aims Blood levels of N‐terminal pro‐brain natriuretic peptide (NT‐proBNP) may be modified by low renal clearance and anaemia. The aim of this study was to investigate the impact of the blood NT‐proBNP level on cardiovascular and renal outcomes in patients with these two manifestations.
Hiroshi Nishi, Masaomi Nangaku, Tadashi Sofue, Tatsuo Kagimura, Ichiei Narita   +4 more
wiley   +1 more source