Results 71 to 80 of about 550,587 (345)
Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang+7 more
wiley +1 more source
Abstract Sodium‐glucose co‐transporters (SGLTs) mediate sodium and glucose transport across cell membranes. SGLT2 inhibitors have a recognized place within heart failure (HF) guidelines. We evaluated the effect of sotagliflozin on HF and cardiovascular outcomes in participants with type 2 diabetes. Scopus, Medline, Embase and Central were searched from
Maria Anna Bantounou+7 more
wiley +1 more source
Since renin inhibition interferes with the first and rate-limiting steps in the renin–angiotensin system, the renin step is a very attractive target for lowering blood pressure and minimizing target-organ damage.
Atsuhiro Ichihara+6 more
doaj
Mechanisms of hypertension during and after orthotopic liver transplantation in children [PDF]
The aim of this study was to assess the hormonal alterations that may mediate the systemic hypertension that develops in patients during the perioperative period of orthotopic liver transplantation.
Akerstedt+72 more
core +1 more source
Abstract Aims Blood levels of N‐terminal pro‐brain natriuretic peptide (NT‐proBNP) may be modified by low renal clearance and anaemia. The aim of this study was to investigate the impact of the blood NT‐proBNP level on cardiovascular and renal outcomes in patients with these two manifestations.
Hiroshi Nishi+4 more
wiley +1 more source
Background: In cirrhotic patients peripheral vasodilatation may decrease renal blood flow and subsequently raises plasma renin activity. Octreotide with several mechanisms causes peripheral arterial vasoconstriction.
Mohammad Minakari+3 more
doaj
The effect of aspirin therapy on the plasma renin activity in myocardial infarction [PDF]
In this study, the changes of renin system activity and the effects of aspirin therapy on the plasma renin activity ( PRA) in myocardial infarction were investigated. Fifty nine patients with myocardial infarction were selected.
M.H Ansari+3 more
doaj
Study the effect of electrode material, its surface, and dielectric material on plasma and properties of plasma-activated water [PDF]
In the present work, the significance of various components (ground electrode material and its surface (knurling pitch size), power electrode material and type, and dielectric material) of dielectric barrier discharge plasma device (DBD-PD) on plasma and plasma-activated water (PAW) properties are studied. The characterization of plasma is performed by
arxiv
Atrial natriuretic factor [PDF]
The discovery of the first well-defined natriuretic hormone, the Atrial Natriuretic Factor (ANF), has prompted research on its impact on volume regulation in health and disease.
A.L. Gerbes+99 more
core +1 more source
Cardiac remodelling in the era of the recommended four pillars heart failure medical therapy
Abstract Cardiac remodelling is a key determinant of worse cardiovascular outcome in patients with heart failure (HF) and reduced ejection fraction (HFrEF). It affects both the left ventricle (LV) structure and function as well as the left atrium (LA) and the right ventricle (RV).
Giada Colombo+7 more
wiley +1 more source