Results 121 to 130 of about 103,129 (319)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Solar Orbiter encounters an unusually high Mach number interplanetary shock

Astronomy & Astrophysics
Aims. The objective of this study is to characterise and understand the magnetic structure of an extremely high Mach number interplanetary shock. Methods.
Dimmock A. P., Boldú J. J., Trotta D., Lalti A., Graham D. B., Lindberg M., Hietala H., Khotyaintsev Yu. V.   +7 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

A complete X-ray view of supernova remnant W28 with the Einstein Probe: Spatial distribution of parameters, and the origin of the thermal-composite morphology

Astronomy & Astrophysics
The question about what causes a supernova remnant (SNR) to be a thermal composite rather than have a typical shell-like morphology remains unsolved, as does what causes the plasma inside it to recombine.
Chi Yi-Heng, Zhou Ping, Chen Yang, Sun Lei, Li Chengkui, Jia Shumei, Chen Yong, Ge Chong, Yuan Weimin   +8 more
doaj   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Aspects of three-dimensional MHD : magnetic reconnection and rotating coronae

, 2010
Solutions of the magnetohydrodynamic (MHD) equations are very important for modelling laboratory, space and astrophysical plasmas, for example the solar and stellar coronae, as well as for modelling many of the dynamic processes that occur in these ...
Al-Salti, Nasser S.
core  

Alfvénic instabilities driven by runaways in fusion plasmas

, 2014
Runaway particles can be produced in plasmas with large electric fields. Here, we address the possibility that such runaway ions and electrons excite Alfvénic instabilities.
T. Fülöp, Fülöp, Tünde, Newton, Sarah, S. Newton, F\ufcl\uf6p, T\ufcnde, Newton, Sarah,, Fülöp, Tünde,   +6 more
core   +1 more source

Discolouration of plasma in therapeutic plasma exchange

Indian Journal of Nephrology, 2021
Bala Kumar, SS Deepak, Fernando, Edwin M., Srinivasaprasad, ND, Valavan, K Thirumal, Sujit, S   +4 more
openaire   +2 more sources

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Ion stopping in dense plasma target for high energy density physics

, 2010
The basic physics of nonrelativistic and electromagnetic ion stopping in hot and ionized plasma targets is thoroughly updated. Corresponding projectile-target interactions involve enhanced projectile ionization and coupling with target free electrons ...
Hasegawa, Jun, Sharkov, Boris Y., Deutsch, Claude, Chabot, Marin, Golubev, Alexey A., Ogawa, Masao, Bimbot, René, Jacoby, Joachim, Couillaud, Christophe, Mintsev, Victor, Della-Negra, Serge, Hoffmann, Dieter H. H., Wahl, H., Weyrich, Karin, Gardes, Daniel, Fleurier, Claude, Fertman, Alexander, Maynard, Gilles, Rivet, Marie-France, Tahir, Naeem Ahmad, Rosmej, Olga N., Fortov, Vladimir E., Oguri, Yoshiyuki   +22 more
core