Results 81 to 90 of about 143,775 (300)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Electron transport in a radiation-dominated plasma

open access: yesAstronomy & Astrophysics
Context. Bremsstrahlung scattering of fast electrons on ions can be enhanced by the microwave radiation present in the solar corona. It can account for the electron diffusive transport along magnetic loops and high precipitation rates.
Duclous R.   +5 more
doaj   +1 more source

Ion‐Scale Kinetic Alfvén Turbulence: MMS Measurements of the Alfvén Ratio in the Magnetosheath

open access: yesGeophysical Research Letters, 2018
Turbulence in the Earth's magnetosheath at ion kinetic scales is investigated with the magnetospheric multiscale spacecraft. Several possibilities in the wave paradigm have been invoked to explain plasma turbulence at ion kinetic scales such as kinetic ...
O. W. Roberts   +12 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Tailoring supported olefin polymerisation catalysts using non-equilibrium plasmas [PDF]

open access: yes, 1999
Supported olefin polymerisation catalysts are used to produce more than 20 million tonnes of polyethylene a year. In this thesis, the application of non- equilibrium plasmas to Phillips, Ziegler-Natta, and metallocene catalysts is described. A Cr(acetate)
Godfrey, Simon Paul
core  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Novel Plasma Source for Dense Plasma Effects

open access: yesPhysical Review Letters, 1995
We describe the production of dense, cool plasmas by the laser ablation of inertially confined foils. Transitions from Al I, Al II, and Al III ions provide the diagnostic information. The electron density ${N}_{e}$ and temperature ${T}_{e}$ are (1-- $3\)\ifmmode\times\else\texttimes\fi{}{10}^{19}{\mathrm{cm}}^{\ensuremath{-}3}$ and 1--8 eV ...
Heading, D, Bennett, G, Wark, J, Lee, R
openaire   +2 more sources

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

The effect of initial conditions on the electromagnetic radiation generation in type III solar radio bursts [PDF]

open access: yes, 2013
Copyright 2013 American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics. This article appeared in Physics of Plasmas 20, 062903 (2013)
Tsiklauri, D   +3 more
core   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

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