Plasmid-Mediated Quinolone Resistance in Shigella flexneri Isolated From Macaques [PDF]
Non-human primates (NHPs) for biomedical research are commonly infected with Shigella spp. that can cause acute dysentery or chronic episodic diarrhea.
Anthony J. Mannion +8 more
doaj +6 more sources
Plasmid-Mediated Quinolone Resistance Genes in Escherichia coli Strains Isolated from Healthy Dogs [PDF]
Knowledge about the potential roles of pets as reservoirs for plasmid-mediated quinolone resistance is still limited in Türkiye. Thus, in our study, the presence of plasmid-mediated quinolone genes (qnrA, qnrB and qnrS) was examined by multiplex ...
Fatma Kalaycı-Yüksek +4 more
doaj +2 more sources
Presence of plasmid-mediated quinolone resistance (PMQR) genes in non-typhoidal Salmonella strains with reduced susceptibility to fluoroquinolones isolated from human salmonellosis in Gyeonggi-do, South Korea from 2016 to 2019 [PDF]
Non-typhoidal salmonellosis remains a pressing public health problem worldwide. Quinolones, particularly fluoroquinolones, are widely used to treat various infections, including non-typhoidal salmonellosis, which can be a serious illness.
Sohyun Lee +7 more
doaj +2 more sources
Quinolone resistance in Riemerella anatipestifer from Thai ducks: Mutation analysis of gyrA, parC, and plasmid-mediated quinolone resistance genes [PDF]
Background and Aim: Riemerella anatipestifer is a Gram-negative bacterium causing systemic infections in ducks, often treated with quinolones. However, increasing resistance to quinolones poses a threat to effective treatment, and the molecular ...
Chutima Pathomchai-Umporn +6 more
doaj +2 more sources
PLASMID-MEDIATED QUINOLONE RESISTANCE – PMQR [PDF]
Katarzyna Piekarska
doaj +2 more sources
Prevalence of plasmid-mediated quinolone resistance determinants among oxyiminocephalosporin-resistant Enterobacteriaceae in Argentina [PDF]
High quinolone resistance rates were observed among oxyiminocephalosporin-resistant enterobacteria. In the present study, we searched for the prevalence of plasmid-mediated quinolone resistance (PMQR) genes within the 55 oxyiminocephalosporin-resistant ...
Giovanna Rincon Cruz +6 more
doaj +6 more sources
Plasmid-Mediated Quinolone Resistance [PDF]
ABSTRACTThree mechanisms for plasmid-mediated quinolone resistance (PMQR) have been discovered since 1998. Plasmid genesqnrA, qnrB, qnrC, qnrD, qnrS,andqnrVCcode for proteins of the pentapeptide repeat family that protects DNA gyrase and topoisomerase IV from quinolone inhibition.
George A, Jacoby +2 more
openaire +3 more sources
Expanded-spectrum β-Lactamase and Plasmid-mediated Quinolone Resistance
To the Editor: The emergence of plasmid-mediated, and thus transferable, quinolone resistance determinants has been recently discovered (1) and shown to involve the pentapeptide repeat protein Qnr, which interacts with DNA gyrase and topoisomerase IV to prevent quinolone inhibition (2,3). Qnr determinants confer resistance to nalidixic acid and reduced
Laurent Poirel +5 more
doaj +4 more sources
Mechanism of plasmid-mediated quinolone resistance [PDF]
Quinolones are potent antibacterial agents that specifically target bacterial DNA gyrase and topoisomerase IV. Widespread use of these agents has contributed to the rise of bacterial quinolone resistance. Previous studies have shown that quinolone resistance arises by mutations in chromosomal genes.
John H, Tran, George A, Jacoby
openaire +2 more sources
BackgroundAntibiotic resistance has become an enduring threat to human health. This has prompted extensive research to identify the determinants responsible in a bid to fight the spread of resistance and also develop new antibiotics.
Jude Fonbah Leinyuy +3 more
doaj +2 more sources

