Aquatic Environments as Hotspots of Transferable Low-Level Quinolone Resistance and Their Potential Contribution to High-Level Quinolone Resistance [PDF]
Antibiotics, 2022 The disposal of antibiotics in the aquatic environment favors the selection of bacteria exhibiting antibiotic resistance mechanisms. Quinolones are bactericidal antimicrobials extensively used in both human and animal medicine.
Claudio D. Miranda +3 more
doaj +3 more sources
Mutational Diversity in the Quinolone Resistance-Determining Regions of Type-II Topoisomerases of Salmonella Serovars [PDF]
Antibiotics, 2021 Quinolone resistance in bacterial pathogens has primarily been associated with mutations in the quinolone resistance-determining regions (QRDRs) of bacterial type-II topoisomerases, which are DNA gyrase and topoisomerase IV. Depending on the position and
Aqsa Shaheen +6 more
doaj +3 more sources
Quinolone resistance: much more than predicted [PDF]
Frontiers in Microbiology, 2011 Since quinolones are synthetic antibiotics, it was predicted that mutations in target genes would be the only mechanism through which resistance could be acquired, because there will not be quinolone resistance genes in nature.
Alvaro eHernandez +2 more
doaj +6 more sources
Quinolone Antibiotics: Resistance and Therapy
Infection and Drug Resistance, 2023 Kai Tang, Heng Zhao Fujian Provincial Key Laboratory of Innate Immune Biology, Fujian Normal University, Fujian, People’s Republic of ChinaCorrespondence: Heng Zhao, Fujian Provincial Key Laboratory of Innate Immune Biology, Fujian Normal University ...
Tang K, Zhao H
doaj +4 more sources
Rapid evolution of fluoroquinolone-resistant
BMC Infectious Diseases, 2011 Background Antibiotic resistance has necessitated fluoroquinolone use but little is known about the selective forces and resistance trajectory in malaria-endemic settings, where selection from the antimalarial chloroquine for fluoroquinolone-resistant ...
Lamikanra Adebayo +6 more
doaj +3 more sources
Word-based GWAS harnesses the rich potential of genomic data for E. coli quinolone resistance [PDF]
Frontiers in Microbiology, 2023 Quinolone resistance presents a growing global health threat. We employed word-based GWAS to explore genomic data, aiming to enhance our understanding of this phenomenon.
Negin Malekian +5 more
doaj +2 more sources
Quinolone Resistance Genes and Their Contribution to Resistance in Vibrio cholerae Serogroup O139 [PDF]
Antibiotics, 2023 Background. Quinolones are commonly used for reducing the duration of diarrhea, infection severity, and limiting further transmission of disease related to Vibrio cholerae, but V. cholerae susceptibility to quinolone decreases over time.
Yan-Yan Zhou +6 more
doaj +2 more sources
Plasmid-Mediated Quinolone Resistance Genes in Escherichia coli Strains Isolated from Healthy Dogs [PDF]
Veterinary SciencesKnowledge about the potential roles of pets as reservoirs for plasmid-mediated quinolone resistance is still limited in Türkiye. Thus, in our study, the presence of plasmid-mediated quinolone genes (qnrA, qnrB and qnrS) was examined by multiplex ...
Fatma Kalaycı-Yüksek +4 more
doaj +2 more sources
Antimicrobial Resistance and Infection Control, 2017 Background Beta-lactam and quinolone antimicrobials are commonly used for treatment of infections caused by non-typhoidal Salmonella (NTS) and other pathogens. Resistance to these classes of antimicrobials has increased significantly in the recent years.
Tadesse Eguale +8 more
doaj +2 more sources
International Journal of Microbiology, 2017 Inappropriate use of antibiotics in clinical settings is thought to have led to the global emergence and spread of multidrug-resistant pathogens. The goal of this study was to investigate the prevalence of genes encoding aminoglycoside resistance and ...
Mohamed F. El-Badawy +7 more
doaj +2 more sources