Results 31 to 40 of about 53,220 (228)
Quinolone Resistance of Actinobacillus pleuropneumoniae Revealed through Genome and Transcriptome Analyses. [PDF]
Int J Mol Sci, 2021 Actinobacillus pleuropneumoniae is a pathogen that infects pigs and poses a serious threat to the pig industry. The emergence of quinolone-resistant strains of A.pleuropneumoniae further limits the choice of treatment.
Ma X +9 more
europepmc +2 more sources
Quinolone resistance in Campylobacter [PDF]
Journal of Antimicrobial Chemotherapy, 2003 assumed that the recording of foreign travel indicated a temporal association. Sensitivity to ciprofloxacin and erythromycin was tested using a disc method. The rates of resistance in individuals with and without a history of recent foreign travel in both the CSSSC and the London groups are shown in Table 1.
openaire +2 more sources
Quinolones: Action and Resistance Updated [PDF]
Current Topics in Medicinal Chemistry, 2009 The quinolones trap DNA gyrase and DNA topoisomerase IV on DNA as complexes in which the DNA is broken but constrained by protein. Early studies suggested that drug binding occurs largely along helix-4 of the GyrA (gyrase) and ParC (topoisomerase IV) proteins.
Drlica, Karl +5 more
openaire +2 more sources
, 2021 Antimicrobial resistance to quinolones, which constitutes a threat to public health, has been increasing worldwide. In this study, we investigated the prevalence of quinolone-resistant determinants in Escherichia coli not susceptible to quinolones and ...
Mingala, Claro +17 more
core +1 more source
Structural insights into the quinolone resistance mechanism of Mycobacterium tuberculosis DNA gyrase. [PDF]
PLoS ONE, 2010 Mycobacterium tuberculosis DNA gyrase, an indispensable nanomachine involved in the regulation of DNA topology, is the only type II topoisomerase present in this organism and is hence the sole target for quinolone action, a crucial drug active against ...
Jérémie Piton +6 more
doaj +1 more source
Clinical Importance and Epidemiology of Quinolone Resistance [PDF]
, 2014 The quinolone class of antimicrobial agents is one of most widely used classes of antimicrobial agents in outpatient and inpatient treatment. However, quinolone resistance in gram-positive and gram-negative bacteria has emerged and increased globally ...
Kim, Eu Suk +3 more
core +1 more source
Quinolone-resistant Escherichia coli [PDF]
Brazilian Journal of Infectious Diseases, 2008 Quinolones (nalidixic acid--NAL, norfloxacin--NOR, ciprofloxacin--CIP and gatifloxacin--GAT) were tested against Escherichia coli isolated from urine (385 patient samples) by disk diffusion (DD) and agar dilution (AD) methods. Fifty-three samples (13.8%) were classified as resistant to at least one of the quinolones tested. CIP and NOR susceptibilities
Ito, Carmen Antonia Sanches +4 more
openaire +4 more sources
, 2020 Plasmid-mediated quinolone resistance (PMQR) remains one of the main mechanisms of bacterial quinolone resistance and plays an important role in the transmission of antibiotic resistance genes (ARGs). In this study, two novel plasmids, p3M-2A and p3M-2B,
Zhenzhou Wu +8 more
core +1 more source
Quinolone resistance mechanisms among extended-spectrum beta-lactamase (ESBL) producing Escherichia coli isolated from rivers and lakes in Switzerland. [PDF]
PLoS ONE, 2014 Sixty extended-spectrum β-lactamase (ESBL)-producing Escherichia coli isolated from rivers and lakes in Switzerland were screened for individual strains additionally exhibiting a reduced quinolone susceptibility phenotype.
Katrin Zurfluh +4 more
doaj +1 more source
Carriage of Class 1 and 2 Integrons in Quinolone, Extended-Spectrum-β-Lactamase-Producing and Multi Drug Resistant E.coli and K.pneumoniae: High Burden of Antibiotic Resistance [PDF]
Advanced Pharmaceutical Bulletin, 2015 Purpose: The study aimed at assessing any association between quinolone resistance, MDR and ESBL production and their relation with the presence of integrons in Esherichia coli and Klebsiella pneumoniae.
Froogh Shams +7 more
doaj +1 more source