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Periodontology 2000, EarlyView., 2023 Abstract This narrative review celebrates Europe's contribution to the current knowledge on systemically administered antimicrobials in periodontal treatment. Periodontitis is the most frequent chronic noncommunicable human disease. It is caused by dysbiotic bacterial biofilms and is commonly treated with subgingival instrumentation.
David Herrera +4 more
wiley +1 more source
Antimicrobial Resistance and Infection Control, 2019 Qnr genes are known to confer a low-level resistance to fluoroquinolone in Enterobacteriaceae. They are often found on the same resistance plasmids as extended spectrum β-lactamase (ESBL) and constitute the most common antibiotic resistance mechanism ...
F. Salah +8 more
semanticscholar +1 more source
Quinolones: Action and Resistance Updated [PDF]
Current Topics in Medicinal Chemistry, 2009 The quinolones trap DNA gyrase and DNA topoisomerase IV on DNA as complexes in which the DNA is broken but constrained by protein. Early studies suggested that drug binding occurs largely along helix-4 of the GyrA (gyrase) and ParC (topoisomerase IV) proteins.
Drlica, Karl +5 more
openaire +2 more sources
Supra and subgingival application of antiseptics or antibiotics during periodontal therapy
Periodontology 2000, EarlyView., 2023 Abstract Periodontal diseases (gingivitis and periodontitis) are characterized by inflammatory processes which arise as a result of disruption of the balance in the oral ecosystem. According to the current S3 level clinical practice guidelines, therapy of patients with periodontitis involves a stepwise approach that includes the control of the patient ...
Elena Figuero +5 more
wiley +1 more source
Transferable Mechanisms of Quinolone Resistance from 1998 Onward
Clinical Microbiology Reviews, 2019 While the description of resistance to quinolones is almost as old as these antimicrobial agents themselves, transferable mechanisms of quinolone resistance (TMQR) remained absent from the scenario for more than 36 years, appearing first as sporadic ...
J. Ruiz
semanticscholar +1 more source
Canadian Journal of Infectious Diseases and Medical Microbiology, 2010 The quinolone resistance-determining regions of gyrA and parC of both quinolone-sensitive and quinolone-resistant Haemophilus parainfluenzae strains were amplified and sequenced.
Dennis KS Law +4 more
doaj +1 more source
Sequence analyses of just four genes to detect extensively drug-resistant Mycobacterium tuberculosis strains in multidrug-resistant tuberculosis patients undergoing treatment [PDF]
, 2009 The rapid detection of Mycobacterium tuberculosis isolates resistant to second-line drugs is crucial for the institution of appropriate treatment regimens as early as possible.
Feuerriegel, S +6 more
core +2 more sources
Quinolone resistance in Campylobacter [PDF]
Journal of Antimicrobial Chemotherapy, 2003 assumed that the recording of foreign travel indicated a temporal association. Sensitivity to ciprofloxacin and erythromycin was tested using a disc method. The rates of resistance in individuals with and without a history of recent foreign travel in both the CSSSC and the London groups are shown in Table 1.
openaire +2 more sources
Quinolone resistance in
BMC Microbiology, 2011 Background Antimicrobial resistance is under-documented and commensal Escherichia coli can be used as indicator organisms to study the resistance in the community.
Lijek Rebeccah S +4 more
doaj +1 more source
Quinolones modulate ghrelin receptor signaling: potential for a novel small molecule scaffold in the treatment of cachexia [PDF]
, 2018 Cachexia is a metabolic wasting disorder characterized by progressive weight loss, muscle atrophy, fatigue, weakness, and appetite loss. Cachexia is associated with almost all major chronic illnesses including cancer, heart failure, obstructive ...
Cano, Rafael +8 more
core +3 more sources