Results 21 to 30 of about 53,220 (228)

Mechanism of action of and resistance to quinolones [PDF]

Microbial Biotechnology, 2008
Summary Fluoroquinolones are an important class of wide‐spectrum antibacterial agents. The first quinolone described was nalidixic acid, which showed a narrow spectrum of activity. The evolution of quinolones to more potent molecules was based on changes at positions 1, 6, 7 and 8 of the chemical structure of ...
Fàbrega, Anna, Madurga, Sergi, Giralt, Ernest, Vila, Jordi   +3 more
openaire   +2 more sources

High-Level Quinolone-Resistant Haemophilus haemolyticus in Pediatric Patient with No History of Quinolone Exposure

Emerging Infectious Diseases, 2022
The prevalence of antimicrobial resistance among Haemophilus spp. is a critical concern, but high-level quinolone-resistant strains had not been isolated from children. We isolated high-level quinolone-resistant H.
Emi Tanaka, Yuji Hirai, Takeaki Wajima, Yu Ishida, Yoshiaki Kawamura, Hidemasa Nakaminami   +5 more
doaj   +1 more source

Plasmid-Mediated Quinolone Resistance [PDF]

Microbiology Spectrum, 2014
ABSTRACTThree mechanisms for plasmid-mediated quinolone resistance (PMQR) have been discovered since 1998. Plasmid genesqnrA, qnrB, qnrC, qnrD, qnrS,andqnrVCcode for proteins of the pentapeptide repeat family that protects DNA gyrase and topoisomerase IV from quinolone inhibition.
George A, Jacoby, Jacob, Strahilevitz, David C, Hooper   +2 more
openaire   +2 more sources

Periodontal microbiology and microbial etiology of periodontal diseases: Historical concepts and contemporary perspectives

Periodontology 2000, EarlyView., 2023
Abstract This narrative review summarizes the collective knowledge on periodontal microbiology, through a historical timeline that highlights the European contribution in the global field. The etiological concepts on periodontal disease culminate to the ecological plaque hypothesis and its dysbiosis‐centered interpretation.
Georgios N. Belibasakis, Daniel Belstrøm, Sigrun Eick, Ulvi K. Gursoy, Anders Johansson, Eija Könönen   +5 more
wiley   +1 more source

Europe's contribution to the evaluation of the use of systemic antimicrobials in the treatment of periodontitis

Periodontology 2000, EarlyView., 2023
Abstract This narrative review celebrates Europe's contribution to the current knowledge on systemically administered antimicrobials in periodontal treatment. Periodontitis is the most frequent chronic noncommunicable human disease. It is caused by dysbiotic bacterial biofilms and is commonly treated with subgingival instrumentation.
David Herrera, Arie Jan van Winkelhoff, Paula Matesanz, Katalina Lauwens, Wim Teughels   +4 more
wiley   +1 more source

Molecular characterization of antimicrobial resistance related genes in E. coli, Salmonella and Klebsiella isolates from broilers in the West Region of Cameroon.

PLoS ONE, 2023
BackgroundAntibiotic resistance has become an enduring threat to human health. This has prompted extensive research to identify the determinants responsible in a bid to fight the spread of resistance and also develop new antibiotics.
Jude Fonbah Leinyuy, Innocent Mbulli Ali, Karimo Ousenu, Christopher B Tume   +3 more
doaj   +2 more sources

Supra and subgingival application of antiseptics or antibiotics during periodontal therapy

Periodontology 2000, EarlyView., 2023
Abstract Periodontal diseases (gingivitis and periodontitis) are characterized by inflammatory processes which arise as a result of disruption of the balance in the oral ecosystem. According to the current S3 level clinical practice guidelines, therapy of patients with periodontitis involves a stepwise approach that includes the control of the patient ...
Elena Figuero, Jorge Serrano, Nicole Birgit Arweiler, Thorsten Mathias Auschill, Ali Gürkan, Gülnur Emingil   +5 more
wiley   +1 more source

Rapid evolution of fluoroquinolone-resistant Escherichia coli in Nigeria is temporally associated with fluoroquinolone use

BMC Infectious Diseases, 2011
Background Antibiotic resistance has necessitated fluoroquinolone use but little is known about the selective forces and resistance trajectory in malaria-endemic settings, where selection from the antimalarial chloroquine for fluoroquinolone-resistant ...
Lamikanra Adebayo, Crowe Jennifer L, Lijek Rebeccah S, Odetoyin Babatunde W, Wain John, Aboderin A Oladipo, Okeke Iruka N   +6 more
doaj   +1 more source

Mechanisms of Resistance to Quinolones [PDF]

Clinical Infectious Diseases, 2005
The increased use of fluoroquinolones has led to increasing resistance to these antimicrobials, with rates of resistance that vary by both organism and geographic region. Resistance to fluoroquinolones typically arises as a result of alterations in the target enzymes (DNA gyrase and topoisomerase IV) and of changes in drug entry and efflux.
openaire   +2 more sources

Sub-inhibitory concentrations of vancomycin prevent quinolone-resistance in a penicillin-resistant isolate of Streptococcus pneumoniae [PDF]

, 2001
BACKGROUND: The continuous spread of penicillin-resistant pneumococci represents a permanent threat in the treatment of pneumococcal infections, especially when strains show additional resistance to quinolones.
Cottagnoud, M, Entenza, JM, Taüber, MG, Moreillon, P, Cottagnoud, P, Que, YA   +5 more
core   +1 more source