Results 21 to 30 of about 3,523,720 (291)

Quinolone-resistant Escherichia coli [PDF]

Brazilian Journal of Infectious Diseases, 2008
Quinolones (nalidixic acid--NAL, norfloxacin--NOR, ciprofloxacin--CIP and gatifloxacin--GAT) were tested against Escherichia coli isolated from urine (385 patient samples) by disk diffusion (DD) and agar dilution (AD) methods. Fifty-three samples (13.8%) were classified as resistant to at least one of the quinolones tested. CIP and NOR susceptibilities
Ito, Carmen Antonia Sanches, Gales, Ana Cristina, Tognim, Maria Cristina B., Munerato, Patrícia, Dalla Costa, Libera Maria   +4 more
openaire   +4 more sources

DNA Gyrase as a Target for Quinolones

Biomedicines, 2023
Bacterial DNA gyrase is a type II topoisomerase that can introduce negative supercoils to DNA substrates and is a clinically-relevant target for the development of new antibacterials. DNA gyrase is one of the primary targets of quinolones, broad-spectrum
Angela C. Spencer, Siva S. Panda
doaj   +1 more source

Detection of S83V GyrA mutation in quinolone-resistant Shewanella algae using comparative genomics

Journal of Microbiology, Immunology and Infection, 2021
Background: Shewanella algae is a zoonotic pathogen that poses a serious health threat to immunocompromised hosts. Treatment of S. algae infections is challenging due to the pathogen's intrinsic resistance to a variety of β-lactam antibiotics ...
Chien-Hao Tseng, Jan-Fang Cheng, Shi-Yu Chen, Wen-Huei Chen, Zhi-Yuan Shi, Yu-Hui Lin, Che-An Tsai, Shih-Ping Lin, Yung-Chun Chen, Yu-Chia Lin, Yao-Ting Huang, Po-Yu Liu   +11 more
doaj   +1 more source

Emerging coexistence of three PMQR genes on a multiple resistance plasmid with a new surrounding genetic structure of qnrS2 in E. coli in China

Antimicrobial Resistance and Infection Control, 2020
Background Quinolones are commonly used for treatment of infections by bacteria of the Enterobacteriaceae family. However, the rising resistance to quinolones worldwide poses a major clinical and public health risk.
Ying Tao, Kaixin Zhou, Lianyan Xie, Yanping Xu, Lizhong Han, Yuxing Ni, Jieming Qu, Jingyong Sun   +7 more
doaj   +1 more source

High-Level Quinolone-Resistant Haemophilus haemolyticus in Pediatric Patient with No History of Quinolone Exposure

Emerging Infectious Diseases, 2022
The prevalence of antimicrobial resistance among Haemophilus spp. is a critical concern, but high-level quinolone-resistant strains had not been isolated from children. We isolated high-level quinolone-resistant H.
Emi Tanaka, Yuji Hirai, Takeaki Wajima, Yu Ishida, Yoshiaki Kawamura, Hidemasa Nakaminami   +5 more
doaj   +1 more source

Antimicrobial Resistance in Clinical Ureaplasma spp. and Mycoplasma hominis and Structural Mechanisms Underlying Quinolone Resistance

Antimicrobial Agents and Chemotherapy, 2020
Antibiotic resistance is a global concern; however, data on antibiotic-resistant Ureaplasma spp. and Mycoplasma hominis are limited in comparison to similar data on other microbes. A total of 492 Ureaplasma spp. and 13 M.
Ting Yang, Lianlian Pan, Ningning Wu, Lin Wang, Zhen Liu, Yingying Kong, Z. Ruan, Xinyou Xie, Jun Zhang   +8 more
semanticscholar   +1 more source

Molecular characterization of antimicrobial resistance related genes in E. coli, Salmonella and Klebsiella isolates from broilers in the West Region of Cameroon.

PLoS ONE, 2023
BackgroundAntibiotic resistance has become an enduring threat to human health. This has prompted extensive research to identify the determinants responsible in a bid to fight the spread of resistance and also develop new antibiotics.
Jude Fonbah Leinyuy, Innocent Mbulli Ali, Karimo Ousenu, Christopher B Tume   +3 more
doaj   +2 more sources

Primer relevamiento de marcadores de resistencia a antibióticos en Enterobacteriaceae en Cochabamba, Bolivia [PDF]

, 2017
Se llevó a cabo un relevamiento molecular de la resistencia a antibióticos de importancia clínica en aislamientos recuperados en Cochabamba, Bolivia. Se estudiaron los genes codificantes de β-lactamasas de espectro extendido y de resistencia a quinolonas
Di Conza, José Alejandro, Gutkind, Gabriel Osvaldo, Radice, Marcela Alejandra, Saba Villarroel, Paola M.   +3 more
core   +1 more source

A Crystal Structure of the Bifunctional Antibiotic Simocyclinone D8, Bound to DNA Gyrase [PDF]

, 2009
Simocyclinones are bifunctional antibiotics that inhibit bacterial DNA gyrase by preventing DNA binding to the enzyme. We report the crystal structure of the complex formed between the N-terminal domain of the Escherichia coli gyrase A subunit and ...
A. Maxwell, A. R. McKay, C. E.M. Stevenson, D. M. Lawson, Flatman, Flatman, Galm, H.-P. Fiedler, L. A. Mitchenall, Laponogov, Lewis, Li, Livermore, M. J. Buttner, M. J. Edwards, Maxwell, Maxwell, Morais Cabral, Oliphant, R. H. Flatman, Ruiz, Schimana, Schoeffler, T. A. Clarke, T. B.K. Le, Theobald, Trefzer, Tsai, Yoshida, Yoshida   +29 more
core   +1 more source

Periodontal microbiology and microbial etiology of periodontal diseases: Historical concepts and contemporary perspectives

Periodontology 2000, EarlyView., 2023
Abstract This narrative review summarizes the collective knowledge on periodontal microbiology, through a historical timeline that highlights the European contribution in the global field. The etiological concepts on periodontal disease culminate to the ecological plaque hypothesis and its dysbiosis‐centered interpretation.
Georgios N. Belibasakis, Daniel Belstrøm, Sigrun Eick, Ulvi K. Gursoy, Anders Johansson, Eija Könönen   +5 more
wiley   +1 more source