Results 41 to 50 of about 53,220 (228)
Antibiotic resistance in the environment, with particular reference to MRSA [PDF]
The introduction of β-lactam antibiotics (penicillins and cephalosporins) in the 1940s and 1950s probably represents the most dramatic event in the battle against infection in human medicine.
William Gaze +13 more
core +1 more source
Establishment of multiplex PCR for detection of genes related to Quinolone resistance
Background/aims: It has been shown that quinolone resistance arises due to mutations in the quinolone resistance-determining regions of the drug targets.
Ngo Tat Trung +4 more
doaj +1 more source
Increased quinolone resistance among typhoid Salmonella isolated from Egyptian patients
Introduction: Typhoid fever is endemic in Egypt; and quinolones are the empirical treatment of choice. There are very limited data reporting quinolone resistance among Egyptian typhoidal Salmonella isolates.
Fatma O.I. Saleh +3 more
doaj +1 more source
Mechanisms of quinolone resistance in Salmonella [PDF]
As in other Gram-negative bacteria, mechanisms of resistance to quinolones in Salmonella include target gene mutations, active efflux, and decreased outer membrane permeability. However, the exact contribution of these individual mechanisms to resistance, which may nevertheless interplay to reach high-level resistance, has not yet clearly been defined ...
Cloeckaert, Axel, Chaslus-Dancla, E.
openaire +5 more sources
Epidemiology of resistance to quinolones in Salmonella [PDF]
Fluoroquinolones account for about 11% of antimicrobial prescriptions in human medicine worldwide and represent the drug of choice for the treatment of a wide range of human infectious diseases. They were introduced into veterinary medicine in Europe in the late 1980s and early 1990s and in the USA in 1995.
Bager, Flemming, Helmuth, Reiner
openaire +3 more sources
Resistance of various pathogens towards quinolones has emerged as a serious threat to combat infections. Analysis of plethora of genes and resistance mechanisms associated with quinolone resistance reveals chromosome-borne and transferable determinants ...
Kittappa eVinothkumar +2 more
doaj +1 more source
ABSTRACT The presence of antibiotics in water not only causes environmental pollution but also increases the growth of antibiotic‐resistant bacterial genes, which pose serious threats to human beings and other water residents. Large numbers of people are reportedly affected by the resistant bacterial genes, as many broad‐spectrum antibiotics are not ...
Amir Zada, Shohreh Azizi
wiley +1 more source
This study analysed the mechanisms of quinolone resistance among enterotoxigenic Escherichia coli (ETEC) in a periurban area of Lima, Peru. The susceptibility to nalidixic acid and ciprofloxacin, the role of Phe-Arg-b-Naphtylamyde inhibitable-(PAbN ...
Pons, M.J. +5 more
core +2 more sources
HOW DOES QUINOLONES ANTIBOTIC RESISTANCE DEVELOP? [PDF]
The quinolone antibiotics arose in the early 1960s, with the first example having a narrow spectrum of activity with unfavourable pharmacokinetics. Over time, the development of new quinolone antibiotics has led to improved equivalents with an expanded ...
Sherine Aly +4 more
doaj +1 more source
Antimicrobial resistance (AMR) is an escalating global threat driven by antimicrobial use in aquaculture and livestock. Resistant pathogens and genes can spread across humans, animals, and the environment through interconnected ecosystems. Using a One Health approach, this review emphasizes antimicrobial stewardship, regulatory strengthening, enhanced ...
Mir Mohammad Ali +10 more
wiley +1 more source

