Results 61 to 70 of about 19,307 (180)

Genomic characterization of antibiotic resistant Escherichia coli isolated from domestic chickens in Pakistan [PDF]

open access: yes, 2019
Poultry husbandry is important for the economic health of Pakistan, but the Pakistani poultry industry is negatively impacted by infections ...
Abbas, Muhammad Athar   +11 more
core   +1 more source

Quinolones modulate ghrelin receptor signaling: potential for a novel small molecule scaffold in the treatment of cachexia [PDF]

open access: yes, 2018
Cachexia is a metabolic wasting disorder characterized by progressive weight loss, muscle atrophy, fatigue, weakness, and appetite loss. Cachexia is associated with almost all major chronic illnesses including cancer, heart failure, obstructive ...
Cano, Rafael   +8 more
core   +3 more sources

Occurrence and characterization of quinolone resistant Escherichia coli from Norwegian turkey meat and complete sequence of an IncX1 plasmid encoding qnrS1.

open access: yesPLoS ONE, 2019
Plasmid-mediated quinolone resistance (PMQR) is frequent among Escherichia coli from various food products and animals in several countries. The objective of this study was to characterize quinolone resistant E.
Jannice Schau Slettemeås   +5 more
doaj   +1 more source

Antimicrobial Effect of Spices and Their Phytochemicals: A Novel Approach to Overcoming Antibiotic Resistance

open access: yesMedComm, Volume 7, Issue 4, April 2026.
This graphical abstract shows the antibacterial potential of phytochemicals from 15 spices, showcasing key compounds, their extraction methods, and mechanisms of action. It highlights membrane disruption, ROS generation, enzyme inhibition, and biofilm prevention as core antibacterial pathways.
Hettiyahandi Binodh De Silva   +3 more
wiley   +1 more source

Plasmid-mediated quinolone resistance in Aeromonas allosaccharophila recovered from a Swiss lake [PDF]

open access: yes, 2017
Objectives To search for plasmid-mediated qnr genes among waterborne environmental Aeromonas spp. recovered from Switzerland. Methods Isolates presenting MICs of nalidixic acid or ciprofloxacin ≥1 mg/L were screened for qnr genes by a multiplex PCR ...
Corvaglia, Anna Rita   +6 more
core  

Serotype epidemiology and multidrug resistance patterns of Salmonella enterica infecting humans in Italy [PDF]

open access: yes, 2016
BACKGROUND: Salmonella enterica is the zoonotic agent most frequently responsible for foodborne infections in humans worldwide. In this work the presence of S.
Bettanello, Sabrina   +4 more
core   +1 more source

Mechanisms of Reduced Susceptibility to Ciprofloxacin in Escherichia coli Isolates from Canadian Hospitals

open access: yesCanadian Journal of Infectious Diseases and Medical Microbiology, 2012
OBJECTIVE: To determine whether plasmid-mediated quinolone resistance (PMQR) determinants play a role in the increasing resistance to fluoroquinolones among Escherichia coli isolates in Canadian hospitals, and to determine the mechanisms of reduced ...
Patricia J Baudry-Simner   +5 more
doaj   +1 more source

Global Analysis of the Co‐Occurrence of Antimicrobial and Metal Resistance Genes in Bacterial Genomes From Dairy‐Isolated Pathogens

open access: yesEnvironmental Microbiology, Volume 28, Issue 4, April 2026.
Metal contamination in dairy systems drives antibiotic resistance through co‐selection. Analysis of 3303 genomes revealed 74% of isolates harbour more metal than AMR genes. Arsenic (arsB) and tetracycline (tet(38)) resistance co‐occur in 43% of bacteria, exhibiting nearly identical prevalence, suggesting a tight genetic linkage.
Arlen Carvalho de Oliveira Almeida   +8 more
wiley   +1 more source

Chlorpromazine inhibits the plasmid-mediated oqxAB multidrug efflux pump in Escherichia coli isolates of Egyptian patients with utis

open access: yesBMC Microbiology
Over the past ten years, the prevalence of the OqxAB efflux pump, a plasmid-mediated quinolone resistance determinant, has increased among Escherichia coli (E. coli) isolates.
Kholoud Baraka   +3 more
doaj   +1 more source

Synthesis, Biological Evaluation, and Theoretical Study of Indenoquinolinylphosphine Oxide Derivatives as Topoisomerase 1 Inhibitors and Antiproliferative Agents

open access: yesChemMedChem, Volume 21, Issue 5, 13 March 2026.
The topoisomerase I inhibition and antiproliferative activities of phosphorated indenoquinoline derivatives were investigated. The target hybrid quinoline and tetrahydroquinoline compounds were synthesized via a two‐step Povarov‐type cycloaddition.
Alba Rodriguez   +5 more
wiley   +1 more source

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